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Eosinophilic Esophagitis (EoE) is an inflammatory esophageal disease which is increasing in prevalence. The diagnostic gold-standard involves manual review of a patient's biopsy tissue sample by a clinical pathologist for the presence of 15…

Image and Video Processing · Electrical Eng. & Systems 2021-01-15 William Adorno , Alexis Catalano , Lubaina Ehsan , Hans Vitzhum von Eckstaedt , Barrett Barnes , Emily McGowan , Sana Syed , Donald E. Brown

Eosinophilic esophagitis (EoE) is a chronic esophageal disorder marked by eosinophil-dominated inflammation. Diagnosing EoE usually involves endoscopic inspection of the esophageal mucosa and obtaining esophageal biopsies for histologic…

Image and Video Processing · Electrical Eng. & Systems 2025-02-07 Juming Xiong , Hou Xiong , Quan Liu , Ruining Deng , Regina N Tyree , Girish Hiremath , Yuankai Huo

Background. Eosinophilic esophagitis (EoE) is an allergic inflammatory condition of the esophagus associated with elevated numbers of eosinophils. Disease diagnosis and monitoring requires determining the concentration of eosinophils in…

Goal: Eosinophilic esophagitis (EoE) is an allergic inflammatory condition characterized by eosinophil accumulation in the esophageal mucosa. EoE diagnosis includes a manual assessment of eosinophil levels in mucosal biopsies - a…

Computer Vision and Pattern Recognition · Computer Science 2021-01-14 Tomer Czyzewski , Nati Daniel , Mark Rochman , Julie M. Caldwell , Garrett A. Osswald , Margaret H. Collins , Marc E. Rothenberg , Yonatan Savir

Eosinophilic esophagitis (EoE) is a chronic allergic inflammatory condition of the esophagus associated with elevated esophageal eosinophils. Second only to gastroesophageal reflux disease, EoE is one of the leading causes of chronic…

Eosinophilic Esophagitis (EoE) represents a challenging condition for medical providers today. The cause is currently unknown, the impact on a patient's daily life is significant, and it is increasing in prevalence. Traditional approaches…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Kevin Lin , Donald Brown , Sana Syed , Adam Greene

Eosinophilic Esophagitis (EoE) is a chronic, immune/antigen-mediated esophageal disease, characterized by symptoms related to esophageal dysfunction and histological evidence of eosinophil-dominant inflammation. Owing to the intricate…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Juming Xiong , Yilin Liu , Ruining Deng , Regina N Tyree , Hernan Correa , Girish Hiremath , Yaohong Wang , Yuankai Huo

Eosinophilic esophagitis (EoE) is a chronic and relapsing disease characterized by esophageal inflammation. Symptoms of EoE include difficulty swallowing, food impaction, and chest pain which significantly impact the quality of life,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Yilin Liu , Ruining Deng , Juming Xiong , Regina N Tyree , Hernan Correa , Girish Hiremath , Yaohong Wang , Yuankai Huo

Eosinophilic esophagitis (EoE) is a chronic, food antigen-driven, allergic inflammatory condition of the esophagus associated with elevated esophageal eosinophils. EoE is a top cause of chronic dysphagia after GERD. Diagnosis of EoE relies…

Deploying deep learning (DL) models in medical applications relies on predictive performance and other critical factors, such as conveying trustworthy predictive uncertainty. Uncertainty estimation (UE) methods provide potential solutions…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Kudaibergen Abutalip , Numan Saeed , Ikboljon Sobirov , Vincent Andrearczyk , Adrien Depeursinge , Mohammad Yaqub

Chronic rhinosinusitis (CRS) is characterized by persistent inflammation in the paranasal sinuses, leading to typical symptoms of nasal congestion, facial pressure, olfactory dysfunction, and discolored nasal drainage, which can…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Yifei Wu , Juming Xiong , Tianyuan Yao , Ruining Deng , Junlin Guo , Jialin Yue , Naweed Chowdhury , Yuankai Huo

Uncertainty quantification in automated image analysis is highly desired in many applications. Typically, machine learning models in classification or segmentation are only developed to provide binary answers; however, quantifying the…

Normally eosinophils are present in the gastrointestinal (GI) tract of healthy individuals. When the eosinophils increase beyond their usual amount in the GI tract, a patient gets varied symptoms. Clinicians find it difficult to diagnose…

Quantitative Methods · Quantitative Biology 2022-11-30 Harsh Shah , Thomas Jacob , Amruta Parulekar , Anjali Amarapurkar , Amit Sethi

Image segmentation is a critical step in computational biomedical image analysis, typically evaluated using metrics like the Dice coefficient during training and validation. However, in clinical settings without manual annotations,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Sikha O K , Meritxell Riera-Marín , Adrian Galdran , Javier García Lopez , Julia Rodríguez-Comas , Gemma Piella , Miguel A. González Ballester

Deep learning based methods for automatic organ segmentation have shown promise in aiding diagnosis and treatment planning. However, quantifying and understanding the uncertainty associated with model predictions is crucial in critical…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Jadie Adams , Shireen Y. Elhabian

We evaluate two different methods for the integration of prediction uncertainty into diagnostic image classifiers to increase patient safety in deep learning. In the first method, Monte Carlo sampling is applied with dropout at test time to…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier

Electroencephalography (EEG) is crucial for the monitoring and diagnosis of brain disorders. However, EEG signals suffer from perturbations caused by non-cerebral artifacts limiting their efficacy. Current artifact detection pipelines are…

Signal Processing · Electrical Eng. & Systems 2021-07-23 Lorena Qendro , Alexander Campbell , Pietro Liò , Cecilia Mascolo

Uncertainty quantification for deep learning is a challenging open problem. Bayesian statistics offer a mathematically grounded framework to reason about uncertainties; however, approximate posteriors for modern neural networks still…

Machine Learning · Statistics 2020-01-23 Nicolas Brosse , Carlos Riquelme , Alice Martin , Sylvain Gelly , Éric Moulines

Accurate segmentation of lesions is crucial for diagnosis and treatment of early esophageal cancer (EEC). However, neither traditional nor deep learning-based methods up to today can meet the clinical requirements, with the mean Dice score…

Image and Video Processing · Electrical Eng. & Systems 2023-06-12 Haipeng Li , Dingrui Liu , Yu Zeng , Shuaicheng Liu , Tao Gan , Nini Rao , Jinlin Yang , Bing Zeng

The full acceptance of Deep Learning (DL) models in the clinical field is rather low with respect to the quantity of high-performing solutions reported in the literature. Particularly, end users are reluctant to rely on the rough…

Image and Video Processing · Electrical Eng. & Systems 2022-10-11 Benjamin Lambert , Florence Forbes , Alan Tucholka , Senan Doyle , Harmonie Dehaene , Michel Dojat
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