Related papers: Simulation-Based Design of Bicuspidization of the …
In this paper we introduce a new method simulating stent graft deployment for assisting endovascular repair of abdominal aortic aneurysms. The method relies on intraoperative images coupled with mechanical models. A multi-step algorithm has…
Many complications in physiology are associated with a deviation in flow in arteries due to a stenosis. The presence of stenosis may transition the flow to weak turbulence. The degree of stenosis as well as its configuration whether…
Patient-specific computational modeling has emerged as a powerful tool for surgical planning in complex congenital heart disease. One promising application is complex biventricular repair, which often requires construction of a custom…
In the context of numerical simulations of the vascular system, local geometric uncertainties have not yet been examined in sufficient detail due to model complexity and the associated large numerical effort. Such uncertainties are related…
The significant rates of post-operative arterial thrombus formation following the sutured anastomosis (surgical connection) of vessels in microvascular reconstruction has kindled the development of engineered solutions such as the UNILINK…
Progressive aneurysmal dilatation is a well-recognized complication in patients with chronic type B aortic dissection (cTBAD), which may lead to a delayed rupture and create a life-threatening condition. However, our understanding of such…
The steady motion and deformation of a lipid-bilayer vesicle translating through a circular tube in low Reynolds number pressure-driven flow are investigated numerically using an axisymmetric boundary element method. This fluid-structure…
This article presents experimental and numerical studies on the effect of free stream turbulence on evolution of flow over an autonomous underwater vehicle (AUV) hull form at three Reynolds numbers with different submergence depths and…
We investigate the influence of expansion geometry on the flow field and turbulence structure in axisymmetric pipe flows through comparative analysis of abrupt ($90^\circ$) and gradual ($45^\circ$) area expansions with an area ratio of 2.56…
Introduction: Increasing interest in real-world evidence has fueled the development of study designs incorporating real-world data (RWD). Using the Causal Roadmap, we specify three designs to evaluate the difference in risk of major adverse…
Does the complex processes of angiogenesis during organism development ultimately lead to a near optimal coronary vasculature in the organs of adult mammals? We examine this hypothesis using a powerful and universal method, built on…
The primary bifurcation of the flow past three-dimensional axisymmetric bodies is investigated. We show that the azimuthal vorticity generated at the body surface is at the root of the instability, and that the mechanism proposed by…
We study the shape, elasticity and fluctuations of the recently predicted (cond-mat/9510172) and subsequently observed (in numerical simulations) (cond-mat/9705059) tubule phase of anisotropic membranes, as well as the phase transitions…
Reduced-order models (ROMs) allow for the simulation of blood flow in patient-specific vasculatures without the high computational cost and wait time associated with traditional computational fluid dynamics (CFD) models. Unfortunately, due…
In many applications free surface flow through rigid porous media has to be modeled. Examples refer to coastal engineering applications as well as geotechnical or biomedical applications. Albeit the frequent applications, slight…
We present a wall model for large-eddy simulation that incorporates surface-roughness effects and is applicable across low- and high-speed flows, for both transitional and fully rough conditions. The model, implemented using an artificial…
Using analytical expressions for the pressure and velocity waveforms in tapered vessels, we construct a linear 1D model for wave propagation in stenotic vessels in the frequency domain. We demonstrate that using only two parameters to…
Abdominal aortic aneurysm (AAA) is a life-threatening condition characterized by permanent enlargement of the aorta, often detected incidentally during imaging for unrelated conditions. Current management relies primarily on aneurysm…
In order to generalize the well-known spanwise-oscillating-wall technique for drag reduction, non-sinusoidal oscillations of a solid wall are considered as a means to alter the skin-friction drag in a turbulent channel flow. A series of…
Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation, a type of valvular heart disease. Metrics derived from blood flows are used to indicate aortic regurgitation onset and evaluate its…