Related papers: Using a probabilistic approach to derive a two-pha…
Granular flows due to simultaneous vertical and horizontal excitations of a flat-bottomed cylindrical pan are investigated using event-driven molecular dynamics simulations. In agreement with recent experimental results, we observe a…
The dynamics of viscous thin-film particle-laden flows down inclined surfaces are commonly modeled with one of two approaches: a diffusive flux model or a suspension balance model. The diffusive flux model assumes that the particles migrate…
The directed migration of cells toward stiffer substrate regions or durotaxis is relevant to tissue development and tumor progression. Here, we introduce a phenomenological model for single cell durotaxis that incorporates both elastic…
Demixing of binary fluids subjected to slow temperature ramps shows repeated waves of nucleation which arise as a consequence of the competition between generation of supersaturation by the temperature ramp and relaxation of supersaturation…
We present a problem-suited numerical method for a particularly challenging cancer invasion model. This model is a multiscale haptotaxis advection-reaction-diffusion system that describes the macroscopic dynamics of two types of cancer…
The 2D flow of a foam confined in a Hele-Shaw cell through a contraction is investigated. Its rheological features are quantified using image analysis, with measurements of the elastic stress, rate of plasticity, and velocity. The behavior…
A growth of malignant neoplasm is considered as a fractional transport approach. We suggested that the main process of the tumor development through a lymphatic net is fractional transport of cells. In the framework of this fractional…
The Lagrangian probability-density-function model, proposed in Part I for dense particle-laden turbulent flows, is validated here against Eulerian-Lagrangian direct numerical simulation (EL) data for different homogeneous flows, namely…
Tumor-immune interactions are central to cancer progression and treatment outcomes. In this study, we present a stochastic agent-based model that integrates cellular heterogeneity, spatial cell-cell interactions, and drug resistance…
In a prototypical mode of single-cell migration, retrograde cytoskeletal flow is mechanically coupled to the environment, propels the cell, and is sustained by an anterograde cytosolic flow of disassembled cytoskeletal components.…
Turbulent motions due to flux-driven thermal convection is investigated by numerical simulations and stochastic modelling. Tilting of convection cells leads to the formation of sheared flows and quasi-periodic relaxation oscillations for…
We study, by means of extensive direct numerical simulations, the turbulent flow produced by a two-dimensional cellular forcing in a cubic box with periodic boundary conditions. In spite of the strong anisotropy of the forcing, we find that…
In this work, a ternary phase-field model for two-phase flows in complex geometries is proposed. In this model, one of the three components in the classical ternary Cahn-Hilliard model is considered as the solid phase, and only one…
Fluidisation is the process by which the weight of a bed of particles is supported by a gas flow passing through it from below. When fluidised materials flow down an incline, the dynamics of the motion differ from their non-fluidised…
We develop a continuous mathematical model of population dynamics that describes the sequential emergence of new genotypes under limited resources. The framework models genotype density as a nonlinear flow in mutation space, combining…
Via computer simulations, we provide evidence that the shear rate induced red blood cell tumbling-to-tank-treading transition also occurs at quite high volume fractions, where collective effects are important. The transition takes place as…
The presence of a dispersed phase can significantly modulate the drag in turbulent systems. We derived a conserved quantity that characterizes the radial transport of azimuthal momentum in the fluid-fluid two-phase Taylor-Couette…
Using formal asymptotic methods we derive a free boundary problem representing one of the simplest mathematical descriptions of the growth and death of a tumour or other biological tissue. The mathematical model takes the form of a closed…
Time-resolved single-cell omics data offers high-throughput, genome-wide measurements of cellular states, which are instrumental to reverse-engineer the processes underpinning cell fate. Such technologies are inherently destructive,…
A thermodynamic approach to rapid phase transformations within a diffuse interface in a binary system is developed. Assuming an extended set of independent thermodynamic variables formed by the union of the classic set of slow variables and…