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Early identification of patients at risk for clinical deterioration in the intensive care unit (ICU) remains a critical challenge. Delayed recognition of impending adverse events, including mortality, vasopressor initiation, and mechanical…

Machine Learning · Computer Science 2026-03-17 Binesh Sadanandan

The multivariate, asynchronous nature of real-world clinical data, such as that generated in Intensive Care Units (ICUs), challenges traditional AI-based decision-support systems. These often assume data regularity and feature independence…

Machine Learning · Computer Science 2025-02-28 Ricardo Santos , André V. Carreiro , Xi Peng , Hugo Gamboa , Holger Fröhlich

Accurate mortality prediction allows Intensive Care Units (ICUs) to adequately benchmark clinical practice and identify patients with unexpected outcomes. Traditionally, simple statistical models have been used to assess patient death risk,…

Machine Learning · Computer Science 2020-05-20 William Caicedo-Torres , Jairo Gutierrez

Chronic obstructive pulmonary disease (COPD) represents a significant global health burden, where precise severity assessment is particularly critical for effective clinical management in intensive care unit (ICU) settings. This study…

Machine Learning · Computer Science 2025-04-29 Akram Shojaei , Mehdi Delrobaei

Intensive care units (ICU) generate long, dense and evolving streams of clinical information, where physicians must repeatedly reassess patient states under time pressure, underscoring a clear need for reliable AI decision support. Existing…

Artificial Intelligence · Computer Science 2026-05-14 Chengzhi Shen , Weixiang Shen , Tobias Susetzky , Chen , Chen , Jun Li , Yuyuan Liu , Xuepeng Zhang , Zhenyu Gong , Daniel Rueckert , Jiazhen Pan

The ability to perform accurate prognosis of patients is crucial for proactive clinical decision making, informed resource management and personalised care. Existing outcome prediction models suffer from a low recall of infrequent positive…

Elderly ICU patients with coexisting diabetes mellitus and heart failure experience markedly elevated short-term mortality, yet few predictive models are tailored to this high-risk group. Diabetes mellitus affects nearly 30% of U.S. adults…

Applications · Statistics 2025-06-19 Junyi Fan , Shuheng Chen , Li Sun , Yong Si , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

The pressure of ever-increasing patient demand and budget restrictions make hospital bed management a daily challenge for clinical staff. Most critical is the efficient allocation of resource-heavy Intensive Care Unit (ICU) beds to the…

Machine Learning · Computer Science 2021-02-25 Emma Rocheteau , Pietro Liò , Stephanie Hyland

Early hospital mortality prediction is critical as intensivists strive to make efficient medical decisions about the severely ill patients staying in intensive care units. As a result, various methods have been developed to address this…

Machine Learning · Computer Science 2019-02-12 Reza Sadeghi , Tanvi Banerjee , William Romine

Providing computational infrastructure for handling diverse intensive care unit (ICU) datasets, the R package 'ricu' enables writing dataset-agnostic analysis code, thereby facilitating multi-center training and validation of machine…

Applications · Statistics 2021-08-03 Nicolas Bennett , Drago Plečko , Ida-Fong Ukor , Nicolai Meinshausen , Peter Bühlmann

We present a pipeline in which unsupervised machine learning techniques are used to automatically identify subtypes of hospital patients admitted between 2017 and 2021 in a large UK teaching hospital. With the use of state-of-the-art…

With the emergence of the Hospital Readmission Reduction Program of the Center for Medicare and Medicaid Services on October 1, 2012, forecasting unplanned patient readmission risk became crucial to the healthcare domain. There are tangible…

Computers and Society · Computer Science 2019-08-22 Avishek Choudhury , Christopher M Greene

In the intensive care unit, the underlying causes of critical illness vary substantially across diagnoses, yet prediction models accounting for diagnostic heterogeneity have not been systematically studied. To address the gap, we evaluate…

Machine Learning · Computer Science 2025-12-09 Mengqi Xu , Subha Maity , Joel Dubin

In intensive care units (ICUs), critically ill patients are monitored with electroencephalograms (EEGs) to prevent serious brain injury. The number of patients who can be monitored is constrained by the availability of trained physicians to…

We study multiple rule-based and machine learning (ML) models for sepsis detection. We report the first neural network detection and prediction results on three categories of sepsis. We have used the retrospective Medical Information Mart…

Machine Learning · Computer Science 2019-03-07 Avijit Mitra , Khalid Ashraf

We used survival analysis to quantify the impact of postdischarge evaluation and management (E/M) services in preventing hospital readmission or death. Our approach avoids a specific pitfall of applying machine learning to this problem,…

Although not without controversy, readmission is entrenched as a hospital quality metric, with statistical analyses generally based on fitting a logistic-Normal generalized linear mixed model. Such analyses, however, ignore death as a…

Clinician burnout poses a substantial threat to patient safety, particularly in high-acuity intensive care units (ICUs). Existing research predominantly relies on retrospective survey tools or broad electronic health record (EHR) metadata,…

Computation and Language · Computer Science 2025-09-08 Syed Ahmad Chan Bukhari , Fazel Keshtkar , Alyssa Meczkowska

Clinical decision making is challenging because of pathological complexity, as well as large amounts of heterogeneous data generated as part of routine clinical care. In recent years, machine learning tools have been developed to aid this…

Hospital Readmissions within 30 days after discharge following Coronary Artery Bypass Graft (CABG) Surgery are substantial contributors to healthcare costs. Many predictive models were developed to identify risk factors for readmissions.…

Machine Learning · Computer Science 2018-12-04 Ramesh B. Manyam , Yanqing Zhang , William B. Keeling , Jose Binongo , Michael Kayatta , Seth Carter
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