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Foundation models for vision have transformed visual recognition with powerful pretrained representations and strong zero-shot capabilities, yet their potential for data-efficient learning remains largely untapped. Active Learning (AL) aims…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Huy Hoang Nguyen , Cédric Jung , Shirin Salehi , Tobias Glück , Anke Schmeink , Andreas Kugi

Integrating the different data modalities of cancer patients can significantly improve the predictive performance of patient survival. However, most existing methods ignore the simultaneous utilization of rich semantic features at different…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Liangrui Pan , Yijun Peng , Yan Li , Yiyi Liang , Liwen Xu , Qingchun Liang , Shaoliang Peng

Genomics, especially multi-omics, has made precision medicine feasible. The completion and publicly accessible multi-omics resource with clinical outcome, such as The Cancer Genome Atlas (TCGA) is a great test bed for developing…

Genomics · Quantitative Biology 2020-08-31 Lana X Garmire

Accurate prognosis of non-small cell lung cancer (NSCLC) patients undergoing immunotherapy is essential for personalized treatment planning, enabling informed patient decisions, and improving both treatment outcomes and quality of life.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Qilong Xing , Zikai Song , Bingxin Gong , Lian Yang , Junqing Yu , Wei Yang

Multimodal deep learning for cancer prognosis is commonly assumed to benefit from synergistic cross-modal interactions, yet this assumption has not been directly tested in survival prediction settings. This work adapts InterSHAP, a Shapley…

Machine Learning · Computer Science 2026-04-15 Iain Swift , JingHua Ye , Ruairi O'Reilly

A cross-modal retrieval process is to use a query in one modality to obtain relevant data in another modality. The challenging issue of cross-modal retrieval lies in bridging the heterogeneous gap for similarity computation, which has been…

Information Retrieval · Computer Science 2019-08-22 Donghuo Zeng

Collaborative game-based learning environments offer rich opportunities for small-group knowledge construction, yet automatically predicting student collaboration satisfaction remains challenging. A critical barrier is modality degradation:…

Machine Learning · Computer Science 2026-05-19 Wen-Hsin Tsai , Chia-Ming Lee , Yuk-Ying Tung

Accurate extraction of molecular representations is a critical step in the drug discovery process. In recent years, significant progress has been made in molecular representation learning methods, among which multi-modal molecular…

Machine Learning · Computer Science 2025-05-13 Rong Yin , Ruyue Liu , Xiaoshuai Hao , Xingrui Zhou , Yong Liu , Can Ma , Weiping Wang

The classification of medical images is a pivotal aspect of disease diagnosis, often enhanced by deep learning techniques. However, traditional approaches typically focus on unimodal medical image data, neglecting the integration of diverse…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Jun-En Ding , Chien-Chin Hsu , Chi-Hsiang Chu , Shuqiang Wang , Feng Liu

With the exponential surge in diverse multi-modal data, traditional uni-modal retrieval methods struggle to meet the needs of users seeking access to data across various modalities. To address this, cross-modal retrieval has emerged,…

Information Retrieval · Computer Science 2024-10-01 Tianshi Wang , Fengling Li , Lei Zhu , Jingjing Li , Zheng Zhang , Heng Tao Shen

In recent years, the growing demand for medical imaging diagnosis has placed a significant burden on radiologists. As a solution, Medical Vision-Language Pre-training (Med-VLP) methods have been proposed to learn universal representations…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Ke Zhang , Yan Yang , Jun Yu , Hanliang Jiang , Jianping Fan , Qingming Huang , Weidong Han

Survival analysis, as a challenging task, requires integrating Whole Slide Images (WSIs) and genomic data for comprehensive decision-making. There are two main challenges in this task: significant heterogeneity and complex inter- and…

Image and Video Processing · Electrical Eng. & Systems 2024-06-17 Conghao Xiong , Hao Chen , Hao Zheng , Dong Wei , Yefeng Zheng , Joseph J. Y. Sung , Irwin King

Cross-modal alignment is crucial for multimodal representation fusion due to the inherent heterogeneity between modalities. While Transformer-based methods have shown promising results in modeling inter-modal relationships, their quadratic…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Yan Li , Yifei Xing , Xiangyuan Lan , Xin Li , Haifeng Chen , Dongmei Jiang

Cross-modality recognition has many important applications in science, law enforcement and entertainment. Popular methods to bridge the modality gap include reducing the distributional differences of representations of different modalities,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Xin Niu , Enyi Li , Jinchao Liu , Yan Wang , Margarita Osadchy , Yongchun Fang

The use of diverse modalities, such as omics, medical images, and clinical data can not only improve the performance of prognostic models but also deepen an understanding of disease mechanisms and facilitate the development of novel…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Maria Boyko , Aleksandra Beliaeva , Dmitriy Kornilov , Alexander Bernstein , Maxim Sharaev

The integration of multi-modal data, such as pathological images and genomic data, is essential for understanding cancer heterogeneity and complexity for personalized treatments, as well as for enhancing survival predictions. Despite the…

Quantitative Methods · Quantitative Biology 2023-01-09 Lin Qiu , Aminollah Khormali , Kai Liu

Multimodal emotion recognition (MER) is crucial for enabling emotionally intelligent systems that perceive and respond to human emotions. However, existing methods suffer from limited cross-modal interaction and imbalanced contributions…

Multimedia · Computer Science 2025-07-30 Zeyu Deng , Yanhui Lu , Jiashu Liao , Shuang Wu , Chongfeng Wei

Modern medicine requires generalised approaches to the synthesis and integration of multimodal data, often at different biological scales, that can be applied to a variety of evidence structures, such as complex disease analyses and…

Quantitative Methods · Quantitative Biology 2019-11-11 Devin Taylor , Simeon Spasov , Pietro Liò

Continual learning is essential for adapting models to new tasks while retaining previously acquired knowledge. While existing approaches predominantly focus on uni-modal data, multi-modal learning offers substantial benefits by utilizing…

Machine Learning · Computer Science 2025-11-11 Evelyn Chee , Wynne Hsu , Mong Li Lee

In medical image segmentation tasks, the domain gap caused by the difference in data collection between training and testing data seriously hinders the deployment of pre-trained models in clinical practice. Continual Test-Time Adaptation…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Xiaogang Du , Jiawei Zhang , Tongfei Liu , Tao Lei , Yingbo Wang