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In clinical practice, crossmodal information including medical images and tabular data is essential for disease diagnosis. There exists a significant modality gap between these data types, which obstructs advancements in crossmodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Tianling Liu , Hongying Liu , Fanhua Shang , Lequan Yu , Tong Han , Liang Wan

Morphological attributes from histopathological images and molecular profiles from genomic data are important information to drive diagnosis, prognosis, and therapy of cancers. By integrating these heterogeneous but complementary data, many…

Machine Learning · Computer Science 2022-02-28 Kaiwen Tan , Weixian Huang , Xiaofeng Liu , Jinlong Hu , Shoubin Dong

Unsupervised domain adaptation for medical image segmentation remains a significant challenge due to substantial domain shifts across imaging modalities, such as CT and MRI. While recent vision-language representation learning methods have…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Lalit Maurya , Honghai Liu , Reyer Zwiggelaar

Leveraging complementary relationships across modalities has recently drawn a lot of attention in multimodal emotion recognition. Most of the existing approaches explored cross-attention to capture the complementary relationships across the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 G Rajasekhar , Jahangir Alam

Multi-modal learning that combines pathological images with genomic data has significantly enhanced the accuracy of survival prediction. Nevertheless, existing methods have not fully utilized the inherent hierarchical structure within both…

Computer Vision and Pattern Recognition · Computer Science 2024-12-05 Ying Chen , Jiajing Xie , Yuxiang Lin , Yuhang Song , Wenxian Yang , Rongshan Yu

Continual Test-Time Adaptation (CTTA) aims to empower perception systems to handle dynamic distribution shifts encountered after deployment. Existing methods predominantly follow a backward-alignment paradigm, which rigidly aligns incoming…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Zhilin Zhu , Yabin Wang , Zhiheng Ma , Yaguang Song , Yaowei Wang , Xiaopeng Hong

Multi-modal learning has shown exceptional performance in various tasks, especially in medical applications, where it integrates diverse medical information for comprehensive diagnostic evidence. However, there still are several challenges…

Machine Learning · Computer Science 2024-11-19 Lin Fan , Yafei Ou , Cenyang Zheng , Pengyu Dai , Tamotsu Kamishima , Masayuki Ikebe , Kenji Suzuki , Xun Gong

We study multimodal survival analysis integrating clinical text, tabular covariates, and genomic profiles using locally deployable large language models (LLMs). As many institutions face tight computational and privacy constraints, this…

Machine Learning · Computer Science 2026-03-24 Moritz Gögl , Christopher Yau

Survival analysis using whole-slide images (WSIs) is crucial in cancer research. Despite significant successes, pathology images typically only provide slide-level labels, which hinders the learning of discriminative representations from…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Chengsheng Zhang , Linhao Qu , Xiaoyu Liu , Zhijian Song

Cancer prognosis is a critical task that involves predicting patient outcomes and survival rates. To enhance prediction accuracy, previous studies have integrated diverse data modalities, such as clinical notes, medical images, and genomic…

Machine Learning · Computer Science 2025-02-04 Jie Peng , Shuang Zhou , Longwei Yang , Yiran Song , Mohan Zhang , Kaixiong Zhou , Feng Xie , Mingquan Lin , Rui Zhang , Tianlong Chen

Cancer survival prediction requires integrating pathological Whole Slide Images (WSIs) and genomic profiles, a challenging task due to the inherent heterogeneity and the complexity of modeling both inter- and intra-modality interactions.…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Mingxin Liu , Chengfei Cai , Jun Li , Pengbo Xu , Jinze Li , Jiquan Ma , Jun Xu

Answering semantically-complicated questions according to an image is challenging in Visual Question Answering (VQA) task. Although the image can be well represented by deep learning, the question is always simply embedded and cannot well…

Computer Vision and Pattern Recognition · Computer Science 2021-12-15 JianJian Cao , Xiameng Qin , Sanyuan Zhao , Jianbing Shen

Test-time adaptation (TTA) enables online model adaptation using only unlabeled test data, aiming to bridge the gap between source and target distributions. However, in multimodal scenarios, varying degrees of distribution shift across…

Machine Learning · Computer Science 2026-03-24 Jiacheng Li , Songhe Feng

Purpose: Immunotherapies have revolutionized the landscape of cancer treatments. However, our understanding of response patterns in advanced cancers treated with immunotherapy remains limited. By leveraging routinely collected noninvasive…

Cancer subtype classification is crucial for personalized treatment and prognostic assessment. However, effectively integrating multi-omic data remains challenging due to the heterogeneous nature of genomic, epigenomic, and transcriptomic…

Machine Learning · Computer Science 2025-06-10 Sajib Acharjee Dip , Uddip Acharjee Shuvo , Dipanwita Mallick , Abrar Rahman Abir , Liqing Zhang

Effective understanding of a disease such as cancer requires fusing multiple sources of information captured across physical scales by multimodal data. In this work, we propose a novel feature embedding module that derives from canonical…

Machine Learning · Computer Science 2021-03-10 Vaishnavi Subramanian , Tanveer Syeda-Mahmood , Minh N. Do

The rapidly emerging field of deep learning-based computational pathology has shown promising results in utilizing whole slide images (WSIs) to objectively prognosticate cancer patients. However, most prognostic methods are currently…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Mingxin Liu , Yunzan Liu , Hui Cui , Chunquan Li , Jiquan Ma

Survival analysis stands as a pivotal process in cancer treatment research, crucial for predicting patient survival rates accurately. Recent advancements in data collection techniques have paved the way for enhancing survival predictions by…

Machine Learning · Computer Science 2024-07-26 Linhao Qu , Dan Huang , Shaoting Zhang , Xiaosong Wang

Accurate survival prediction is essential for personalized cancer treatment. However, genomic data - often a more powerful predictor than pathology data - is costly and inaccessible. We present the cross-modal genomic feature translation…

Image and Video Processing · Electrical Eng. & Systems 2024-11-04 Akhila Krishna , Nikhil Cherian Kurian , Abhijeet Patil , Amruta Parulekar , Amit Sethi

Cancer prognosis and survival outcome predictions are crucial for therapeutic response estimation and for stratifying patients into various treatment groups. Medical domains concerned with cancer prognosis are abundant with multiple…

Image and Video Processing · Electrical Eng. & Systems 2024-02-29 Ruining Deng , Nazim Shaikh , Gareth Shannon , Yao Nie