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Deep learning (DL) has substantially enhanced natural language processing (NLP) in healthcare research. However, the increasing complexity of DL-based NLP necessitates transparent model interpretability, or at least explainability, for…

Computation and Language · Computer Science 2024-10-17 Guangming Huang , Yingya Li , Shoaib Jameel , Yunfei Long , Giorgos Papanastasiou

With the advances in artificial intelligence (AI), data-driven algorithms are becoming increasingly popular in the medical domain. However, due to the nonlinear and complex behavior of many of these algorithms, decision-making by such…

Quantitative Methods · Quantitative Biology 2024-07-18 Amirehsan Ghasemi , Soheil Hashtarkhani , David L Schwartz , Arash Shaban-Nejad

Explainable Artificial Intelligence (XAI) aims to create transparency in modern AI models by offering explanations of the models to human users. There are many ways in which researchers have attempted to evaluate the quality of these XAI…

Human-Computer Interaction · Computer Science 2025-11-07 Joe Shymanski , Jacob Brue , Sandip Sen

Despite its technological breakthroughs, eXplainable Artificial Intelligence (XAI) research has limited success in producing the {\em effective explanations} needed by users. In order to improve XAI systems' usability, practical…

Human-Computer Interaction · Computer Science 2024-03-22 Thu Nguyen , Alessandro Canossa , Jichen Zhu

Explainable Artificial Intelligence (XAI) aims to improve the transparency of machine learning (ML) pipelines. We systematize the increasingly growing (but fragmented) microcosm of studies that develop and utilize XAI methods for defensive…

Cryptography and Security · Computer Science 2023-03-06 Azqa Nadeem , Daniël Vos , Clinton Cao , Luca Pajola , Simon Dieck , Robert Baumgartner , Sicco Verwer

Explainable machine learning (ML) enables human learning from ML, human appeal of automated model decisions, regulatory compliance, and security audits of ML models. Explainable ML (i.e. explainable artificial intelligence or XAI) has been…

Machine Learning · Statistics 2019-12-03 Patrick Hall , Navdeep Gill , Nicholas Schmidt

Explainable Artificial Intelligence (XAI) is transforming the field of Artificial Intelligence (AI) by enhancing the trust of end-users in machines. As the number of connected devices keeps on growing, the Internet of Things (IoT) market…

Artificial Intelligence · Computer Science 2022-11-08 Senthil Kumar Jagatheesaperumal , Quoc-Viet Pham , Rukhsana Ruby , Zhaohui Yang , Chunmei Xu , Zhaoyang Zhang

Research around AI for Science has seen significant success since the rise of deep learning models over the past decade, even with longstanding challenges such as protein structure prediction. However, this fast development inevitably made…

Artificial Intelligence · Computer Science 2022-12-27 Kieran Didi , Matej Zečević

The implementation of Artificial Intelligence (AI) systems in the manufacturing domain enables higher production efficiency, outstanding performance, and safer operations, leveraging powerful tools such as deep learning and reinforcement…

Artificial Intelligence · Computer Science 2021-07-07 Georgios Sofianidis , Jože M. Rožanec , Dunja Mladenić , Dimosthenis Kyriazis

In a recent paper, Erasmus et al. (2021) defend the idea that the ambiguity of the term "explanation" in explainable AI (XAI) can be solved by adopting any of four different extant accounts of explanation in the philosophy of science: the…

Artificial Intelligence · Computer Science 2024-03-04 Andrés Páez

Modern AI systems frequently rely on opaque black-box models, most notably Deep Neural Networks, whose performance stems from complex architectures with millions of learned parameters. While powerful, their complexity poses a major…

Machine Learning · Computer Science 2026-02-23 David Dembinsky , Adriano Lucieri , Stanislav Frolov , Hiba Najjar , Ko Watanabe , Andreas Dengel

Recent advancements in Artificial Intelligence (AI) have transformed decision-making in aeronautics and aerospace. These advancements in AI have brought with them the need to understand the reasons behind the predictions generated by AI…

Big Data has become central to modern applications in finance, insurance, and cybersecurity, enabling machine learning systems to perform large-scale risk assessments and fraud detection. However, the increasing dependence on automated…

Machine Learning · Computer Science 2025-12-19 Ayush Jain , Rahul Kulkarni , Siyi Lin

Given the complexity and lack of transparency in deep neural networks (DNNs), extensive efforts have been made to make these systems more interpretable or explain their behaviors in accessible terms. Unlike most reviews, which focus on…

Artificial Intelligence · Computer Science 2024-01-17 Haoyi Xiong , Xuhong Li , Xiaofei Zhang , Jiamin Chen , Xinhao Sun , Yuchen Li , Zeyi Sun , Mengnan Du

Deep learning has become popular because of its potential to achieve high accuracy in prediction tasks. However, accuracy is not always the only goal of statistical modelling, especially for models developed as part of scientific research.…

Machine Learning · Computer Science 2021-10-19 Thomas P Quinn , Sunil Gupta , Svetha Venkatesh , Vuong Le

The surge in black-box AI models has prompted the need to explain the internal mechanism and justify their reliability, especially in high-stakes applications, such as healthcare and autonomous driving. Due to the lack of a rigorous…

Artificial Intelligence · Computer Science 2024-03-18 Yongjie Wang , Tong Zhang , Xu Guo , Zhiqi Shen

This paper systematically reviews recent advances in artificial intelligence (AI), with a particular focus on machine learning (ML), across the entire drug discovery pipeline. Due to the inherent complexity, escalating costs, prolonged…

Artificial Intelligence · Computer Science 2025-07-08 Junwei Su , Cheng Xin , Ao Shang , Shan Wu , Zhenzhen Xie , Ruogu Xiong , Xiaoyu Xu , Cheng Zhang , Guang Chen , Yau-Tuen Chan , Guoyi Tang , Ning Wang , Yong Xu , Yibin Feng

Recent years have seen a surge of interest in the field of explainable AI (XAI), with a plethora of algorithms proposed in the literature. However, a lack of consensus on how to evaluate XAI hinders the advancement of the field. We…

Artificial Intelligence · Computer Science 2022-09-22 Q. Vera Liao , Yunfeng Zhang , Ronny Luss , Finale Doshi-Velez , Amit Dhurandhar

Artificial intelligence is creating one of the biggest revolution across technology driven application fields. For the finance sector, it offers many opportunities for significant market innovation and yet broad adoption of AI systems…

Risk Management · Quantitative Finance 2022-12-07 Marc Wildi , Branka Hadji Misheva

Despite promising developments in Explainable Artificial Intelligence, the practical value of XAI methods remains under-explored and insufficiently validated in real-world settings. Robust and context-aware evaluation is essential, not only…

Human-Computer Interaction · Computer Science 2025-06-18 Ivania Donoso-Guzmán , Kristýna Sirka Kacafírková , Maxwell Szymanski , An Jacobs , Denis Parra , Katrien Verbert