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Radiology reports are a rich resource for advancing deep learning applications in medicine by leveraging the large volume of data continuously being updated, integrated, and shared. However, there are significant challenges as well, largely…

Information Retrieval · Computer Science 2017-11-21 Imon Banerjee , Sriraman Madhavan , Roger Eric Goldman , Daniel L. Rubin

This paper proposes a possible method using natural language processing that might assist in the FDA medical device marketing process. Actual device descriptions are taken and matched with the device description in FDA Title 21 of CFR to…

Computation and Language · Computer Science 2022-12-05 Zongzhe Xu

This study investigates the use of unsupervised word embeddings and sequence features for sample representation in an active learning framework built to extract clinical concepts from clinical free text. The objective is to further reduce…

Computation and Language · Computer Science 2016-11-16 Mahnoosh Kholghi , Lance De Vine , Laurianne Sitbon , Guido Zuccon , Anthony Nguyen

Natural language processing (NLP) is utilized in a wide range of fields, where words in text are typically transformed into feature vectors called embeddings. BioConceptVec is a specific example of embeddings tailored for biology, trained…

Computation and Language · Computer Science 2025-05-28 Hiroaki Yamagiwa , Ryoma Hashimoto , Kiwamu Arakane , Ken Murakami , Shou Soeda , Momose Oyama , Yihua Zhu , Mariko Okada , Hidetoshi Shimodaira

Liquid chromatography coupled with tandem mass spectrometry, also known as shotgun proteomics, is a widely-used high-throughput technology for identifying proteins in complex biological samples. Analysis of the tens of thousands of…

Molecular Networks · Quantitative Biology 2014-10-30 Shengjie Wang , John T. Halloran , Jeff A. Bilmes , William S. Noble

Weakly-supervised text classification aims to train a classifier using only class descriptions and unlabeled data. Recent research shows that keyword-driven methods can achieve state-of-the-art performance on various tasks. However, these…

Computation and Language · Computer Science 2022-12-16 Tingyu Xia , Yue Wang , Yuan Tian , Yi Chang

The process of identifying and characterizing B-cell epitopes, which are the portions of antigens recognized by antibodies, is important for our understanding of the immune system, and for many applications including vaccine development,…

Quantitative Methods · Quantitative Biology 2025-12-10 Xiao Yuan

The Sequential Sentence Classification task within the domain of medical abstracts, termed as SSC, involves the categorization of sentences into pre-defined headings based on their roles in conveying critical information in the abstract. In…

Computation and Language · Computer Science 2024-06-03 Phat Lam , Lam Pham , Tin Nguyen , Hieu Tang , Michael Seidl , Medina Andresel , Alexander Schindler

Social scientists often classify text documents to use the resulting labels as an outcome or a predictor in empirical research. Automated text classification has become a standard tool, since it requires less human coding. However, scholars…

Computation and Language · Computer Science 2025-05-14 Mitchell Bosley , Saki Kuzushima , Ted Enamorado , Yuki Shiraito

Text embedding models play a crucial role in natural language processing, particularly in information retrieval, and their importance is further highlighted with the recent utilization of RAG (Retrieval- Augmented Generation). This study…

Information Retrieval · Computer Science 2024-12-24 Jeongsu Yu

Precise breast cancer classification on histopathological images has the potential to greatly improve the diagnosis and patient outcome in oncology. The data imbalance problem largely stems from the inherent imbalance within medical image…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Majid Behzadpour , Bengie L. Ortiz , Ebrahim Azizi , Kai Wu

Most unsupervised NLP models represent each word with a single point or single region in semantic space, while the existing multi-sense word embeddings cannot represent longer word sequences like phrases or sentences. We propose a novel…

Computation and Language · Computer Science 2021-12-30 Haw-Shiuan Chang , Amol Agrawal , Andrew McCallum

Personalized cancer vaccines are envisioned as the next generation rational cancer immunotherapy. The key step in developing personalized therapeutic cancer vaccines is to identify tumor-specific neoantigens that are on the surface of tumor…

Machine Learning · Computer Science 2019-05-23 Rui Qiao , Ngoc Hieu Tran , Lei Xin , Baozhen Shan , Ming Li , Ali Ghodsi

In recent years, with the development of quantum machine learning, quantum neural networks (QNNs) have gained increasing attention in the field of natural language processing (NLP) and have achieved a series of promising results. However,…

Quantum Physics · Physics 2024-05-24 Yixiong Chen , Weichuan Fang

Metaproteomics are becoming widely used in microbiome research for gaining insights into the functional state of the microbial community. Current metaproteomics studies are generally based on high-throughput tandem mass spectrometry (MS/MS)…

Quantitative Methods · Quantitative Biology 2020-09-24 Xuan Guo , Shichao Feng

In this paper, an improved clustering technique for large textual datasets by leveraging fine-tuned word embeddings is presented. WEClustering technique is used as the base model. WEClustering model is fur-ther improvements incorporating…

Machine Learning · Computer Science 2025-05-22 Vijay Kumar Sutrakar , Nikhil Mogre

Computational and machine learning approaches to model the conformational landscape of macrocyclic peptides have the potential to enable rational design and optimization. However, accurate, fast, and scalable methods for modeling macrocycle…

Biomolecules · Quantitative Biology 2024-08-12 Colin A. Grambow , Hayley Weir , Christian N. Cunningham , Tommaso Biancalani , Kangway V. Chuang

Circulating tumor cells (CTCs) are crucial biomarkers in liquid biopsy, offering a noninvasive tool for cancer patient management. However, their identification remains particularly challenging due to their limited number and heterogeneity.…

Image and Video Processing · Electrical Eng. & Systems 2025-11-24 Martina Russo , Giulia Bertolini , Vera Cappelletti , Cinzia De Marco , Serena Di Cosimo , Petra Paiè , Nadia Brancati

In recent years, there has been an explosion of research on the application of deep learning to the prediction of various peptide properties, due to the significant development and market potential of peptides. Molecular dynamics has…

Biomolecules · Quantitative Biology 2023-07-19 Zihan Liu , Jiaqi Wang , Yun Luo , Shuang Zhao , Wenbin Li , Stan Z. Li

In this work, we apply word embeddings and neural networks with Long Short-Term Memory (LSTM) to text classification problems, where the classification criteria are decided by the context of the application. We examine two applications in…

Computation and Language · Computer Science 2016-07-15 Adithya Rao , Nemanja Spasojevic