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In this work, we introduce the task of life-long personalization of large language models. While recent mainstream efforts in the LLM community mainly focus on scaling data and compute for improved capabilities of LLMs, we argue that it is…

Computation and Language · Computer Science 2024-12-18 Tiannan Wang , Meiling Tao , Ruoyu Fang , Huilin Wang , Shuai Wang , Yuchen Eleanor Jiang , Wangchunshu Zhou

Transformer-based large language models (LLMs) have demonstrated impressive capabilities in a variety of natural language processing (NLP) tasks. Nonetheless, it is challenging to deploy and fine-tune LLMs on mobile edge devices with…

Machine Learning · Computer Science 2023-11-23 Yuhao Chen , Yuxuan Yan , Qianqian Yang , Yuanchao Shu , Shibo He , Jiming Chen

Large language models (LLMs) face the challenges in fine-tuning and deployment due to their high memory demands and computational costs. While parameter-efficient fine-tuning (PEFT) methods aim to reduce the memory usage of the optimizer…

Machine Learning · Computer Science 2023-10-31 Jeonghoon Kim , Jung Hyun Lee , Sungdong Kim , Joonsuk Park , Kang Min Yoo , Se Jung Kwon , Dongsoo Lee

In this paper, we introduce a novel learning paradigm for Adaptive Large Language Model (LLM) agents that eliminates the need for fine-tuning the underlying LLMs. Existing approaches are often either rigid, relying on static, handcrafted…

Machine Learning · Computer Science 2025-08-26 Huichi Zhou , Yihang Chen , Siyuan Guo , Xue Yan , Kin Hei Lee , Zihan Wang , Ka Yiu Lee , Guchun Zhang , Kun Shao , Linyi Yang , Jun Wang

Continuing advances in Large Language Models (LLMs) in artificial intelligence offer important capacities in intuitively accessing and using medical knowledge in many contexts, including education and training as well as assessment and…

Computation and Language · Computer Science 2024-08-01 Roma Shusterman , Allison C. Waters , Shannon O`Neill , Phan Luu , Don M. Tucker

The shortage of clinical workforce presents significant challenges in mental healthcare, limiting access to formal diagnostics and services. We aim to tackle this shortage by integrating a customized large language model (LLM) into the…

Computation and Language · Computer Science 2025-05-02 Sichang Tu , Abigail Powers , Natalie Merrill , Negar Fani , Sierra Carter , Stephen Doogan , Jinho D. Choi

Recently, Large Language Models (LLM) have demonstrated impressive capability to solve a wide range of tasks. However, despite their success across various tasks, no prior work has investigated their capability in the biomedical domain yet.…

Computation and Language · Computer Science 2024-02-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

Since individuals may struggle to recall all life details and often confuse events, establishing a system to assist users in recalling forgotten experiences is essential. While numerous studies have proposed memory recall systems, these…

Computation and Language · Computer Science 2026-02-26 Chia Cheng Chang , An-Zi Yen , Hen-Hsen Huang , Hsin-Hsi Chen

The recent progress of large language models (LLMs), including ChatGPT and GPT-4, in comprehending and responding to human instructions has been remarkable. Nevertheless, these models typically perform better in English and have not been…

Computation and Language · Computer Science 2023-04-18 Honglin Xiong , Sheng Wang , Yitao Zhu , Zihao Zhao , Yuxiao Liu , Linlin Huang , Qian Wang , Dinggang Shen

Parameter-Efficient Fine-Tuning (PEFT) is widely used for adapting Large Language Models (LLMs) for various tasks. Recently, there has been an increasing demand for fine-tuning a single LLM for multiple tasks because it requires overall…

Computation and Language · Computer Science 2026-05-15 Anjir Ahmed Chowdhury , Syed Zawad , Xiaolong Ma , Xu Dong , Feng Yan

Large Audio Language Models (LALMs) have expanded the interaction with human to speech modality, which introduces great interactive potential, due to the paralinguistic cues implicitly indicating the user context. However, building on the…

Sound · Computer Science 2026-03-13 Hao Yang , Minghan Wang , Tongtong Wu , Lizhen Qu , Ehsan Shareghi , Gholamreza Haffari

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

The advanced large language model (LLM) ChatGPT has shown its potential in different domains and remains unbeaten due to its characteristics compared to other LLMs. This study aims to evaluate the potential of using a fine-tuned ChatGPT…

Computation and Language · Computer Science 2023-12-20 Md. Rafiul Biswas , Ashhadul Islam , Zubair Shah , Wajdi Zaghouani , Samir Brahim Belhaouari

There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…

Large Language Models (LLMs), prominently highlighted by the recent evolution in the Generative Pre-trained Transformers (GPT) series, have displayed significant prowess across various domains, such as aiding in healthcare diagnostics and…

Portfolio Management · Quantitative Finance 2023-09-08 Yang Li , Yangyang Yu , Haohang Li , Zhi Chen , Khaldoun Khashanah

Large Language Models (LLMs) have demonstrated remarkable capabilities, yet their transition to real-world applications reveals a critical limitation: the inability to adapt to individual preferences while maintaining alignment with…

Computation and Language · Computer Science 2025-05-06 Jian Guan , Junfei Wu , Jia-Nan Li , Chuanqi Cheng , Wei Wu

Large Language Models (LLMs) represent a landmark achievement in Artificial Intelligence (AI), demonstrating unprecedented proficiency in procedural tasks such as text generation, code completion, and conversational coherence. These…

Artificial Intelligence · Computer Science 2025-05-07 Schaun Wheeler , Olivier Jeunen

Large Language Models (LLMs) have demonstrated remarkable human-like capabilities, yet their ability to replicate a specific individual remains under-explored. This paper presents a case study to investigate LLM-based individual simulation…

Computation and Language · Computer Science 2026-03-03 Minghao Guo , Ziyi Ye , Wujiang Xu , Xi Zhu , Wenyue Hua , Dimitris N. Metaxas

The integration of Large Language Models (LLMs) into medical applications has sparked widespread interest across the healthcare industry, from drug discovery and development to clinical decision support, assisting telemedicine, medical…

Computation and Language · Computer Science 2024-12-03 Zifeng Wang , Hanyin Wang , Benjamin Danek , Ying Li , Christina Mack , Hoifung Poon , Yajuan Wang , Pranav Rajpurkar , Jimeng Sun

Large language models (LLMs) like GPTs, trained on vast datasets, have demonstrated impressive capabilities in language understanding, reasoning, and planning, achieving human-level performance in various tasks. Most studies focus on…

Artificial Intelligence · Computer Science 2025-05-13 Xun Jiang , Feng Li , Han Zhao , Jiahao Qiu , Jiaying Wang , Jun Shao , Shihao Xu , Shu Zhang , Weiling Chen , Xavier Tang , Yize Chen , Mengyue Wu , Weizhi Ma , Mengdi Wang , Tianqiao Chen
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