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Electroencephalography (EEG) is a neuroimaging technique that records brain neural activity with high temporal resolution. Unlike other methods, EEG does not require prohibitively expensive equipment and can be easily set up using…

Human-Computer Interaction · Computer Science 2024-10-01 Arash Akbarinia

Single particle, cryogenic electron microscopy (cryo-EM) experiments now routinely produce high-resolution data for large proteins and their complexes. Building an atomic model into a cryo-EM density map is challenging, particularly when no…

Biomolecules · Quantitative Biology 2020-09-04 Po-Nan Li , Saulo H. P. de Oliveira , Soichi Wakatsuki , Henry van den Bedem

Cryogenic electron microscopy (cryo-EM) provides images from different copies of the same biomolecule in arbitrary orientations. Here, we present an end-to-end unsupervised approach that learns individual particle orientations from cryo-EM…

Image and Video Processing · Electrical Eng. & Systems 2021-07-08 Youssef S. G. Nashed , Frederic Poitevin , Harshit Gupta , Geoffrey Woollard , Michael Kagan , Chuck Yoon , Daniel Ratner

Cryogenic electron microscopy (Cryo-EM) has become an essential tool for capturing high-resolution biological structures. Despite its advantage in visualizations, the large storage size of Cryo-EM data file poses significant challenges for…

Machine Learning · Computer Science 2025-12-16 Chunyu Zou

Spectroscopic mapping by scanning transmission electron microscopy coupled with electron energy loss spectroscopy (STEM-EELS) is a powerful technique for determining the structure and chemistry of a wide range of materials and interfaces.…

Materials Science · Physics 2020-07-21 Berit H. Goodge , David J. Baek , Lena F. Kourkoutis

Accurate localization is fundamental to a variety of applications, such as navigation, robotics, autonomous driving, and Augmented Reality (AR). Different from incremental localization, global localization has no drift caused by error…

Robotics · Computer Science 2021-03-30 Kejie Qiu , Shenzhou Chen , Jiahui Zhang , Rui Huang , Le Cui , Siyu Zhu , Ping Tan

Advances in imagery at atomic and near-atomic resolution, such as cryogenic electron microscopy (cryo-EM), have led to an influx of high resolution images of proteins and other macromolecular structures to data banks worldwide. Producing a…

Quantitative Methods · Quantitative Biology 2021-04-06 Nathan Ranno , Dong Si

Cryo-electron tomography (cryo-ET) provides a unique window into molecular organization in cellular environments (in situ). However, the interpretation of molecular structural information is complicated by several intrinsic properties of…

Biomolecules · Quantitative Biology 2026-02-17 Slavica Jonic

Electrocardiogram (ECG) recordings have long been vital in diagnosing different cardiac conditions. Recently, research in the field of automatic ECG processing using machine learning methods has gained importance, mainly by utilizing deep…

The contributions of this thesis stem from technology developed to analyse large sets of volumetric images in terms of atom-like features extracted in 3D image space, following SIFT algorithm in 2D image space. New feature properties are…

Image and Video Processing · Electrical Eng. & Systems 2022-08-29 Laurent Chauvin

Single particle cryo-electron microscopy has become a critical tool in structural biology over the last decade, able to achieve atomic scale resolution in three dimensional models from hundreds of thousands of (noisy) two-dimensional…

Numerical Analysis · Mathematics 2023-07-19 Aaditya V. Rangan , Leslie Greengard

Cryo-electron microscopy (cryo-EM) extracts single-particle density projections of individual biomolecules. Although cryo-EM is widely used for 3D reconstruction, due to its single-particle nature, it has the potential to provide…

Semantic correspondence made tremendous progress through the recent advancements of large vision models (LVM). While these LVMs have been shown to reliably capture local semantics, the same can currently not be said for capturing global…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Krispin Wandel , Hesheng Wang

Existing unsupervised image alignment methods exhibit limited accuracy and high computational complexity. To address these challenges, we propose a dense cross-scale image alignment model. It takes into account the correlations between…

Computer Vision and Pattern Recognition · Computer Science 2025-11-13 Jinkun You , Jiaxue Li , Jie Zhang , Yicong Zhou

Entity alignment has always had significant uses within a multitude of diverse scientific fields. In particular, the concept of matching entities across networks has grown in significance in the world of social science as communicative…

Social and Information Networks · Computer Science 2020-04-21 James Flamino , Christopher Abriola , Ben Zimmerman , Zhongheng Li , Joel Douglas

Cross-view geo-localization aims at establishing location correspondences between different viewpoints. Existing approaches typically learn cross-view correlations through direct feature similarity matching, often overlooking semantic…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Hongyang Zhang , Yinhao Liu , Zhenyu Kuang

Single particle cryo-electron microscopy is a vital tool for 3D characterization of protein structures. A typical workflow involves acquiring projection images of a collection of randomly oriented particles, picking and classifying…

Image and Video Processing · Electrical Eng. & Systems 2021-03-22 S. V. Venkatakrishnan , Puneet Juneja , Hugh O'Neill

We present initial results on the use of Mixture Models for density estimation in large astronomical databases. We provide herein both the theoretical and experimental background for using a mixture model of Gaussians based on the…

Astrophysics · Physics 2007-05-23 R. C. Nichol , A. J. Connolly , A. W. Moore , J. Schneider , C. Genovese , L. Wasserman

Cryo-EM is a vital technique for determining 3D structure of biological molecules such as proteins and viruses. The cryo-EM reconstruction problem is challenging due to the high noise levels, the missing poses of particles, and the…

Quantitative Methods · Quantitative Biology 2024-06-05 Larissa de Ruijter , Gabriele Cesa

Cryo-electron tomography (cryoET) is a technique that captures images of biological samples at different tilts, preserving their native state as much as possible. Along with the partial tilt series and noise, one of the major challenges in…

Signal Processing · Electrical Eng. & Systems 2023-07-26 Vinith Kishore , Valentin Debarnot , Ivan Dokmanić