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Liquids serve microcavity research ever since Ashkins studies on optical resonances in levitating droplets to recent optofluidic resonators. Droplets can provide optical quality factor (Q) in proximity to the limit restricted by water…
Microchip electrokinetic methods are capable of increasing the sensitivity of molecular assays by enriching and purifying target analytes. However, their use is currently limited to assays that can be performed under a high external…
This work describes a new microfluidic device developed for rapid screening of solubility diagrams. In several parallel channels, hundreds of nanoliter-volume droplets of a given solution are first stored with a gradual variation in the…
This study presents a three-dimensional transient computational fluid dynamics simulation of droplet generation in a flow-focusing microfluidic device using the Coupled Level Set and Volume of Fluid method for interface capturing. We…
Water vapor condensation is common in nature and widely used in industrial applications, including water harvesting, power generation, and desalination. As compared to traditional filmwise condensation, dropwise condensation on…
The evaporation of multi-component droplets is relevant to various applications but challenging to study due to the complex physicochemical dynamics. Recently, Li (2018) reported evaporation-triggered segregation in 1,2-hexanediol-water…
Microcapsules with liquid cores encapsulated by thin membranes have many applications in science, medicine and industry. In this paper, we design a suspension of microcapsules which flow and deform like red blood cells (RBCs), as a valuable…
We present Tuna-step, a novel microfluidic module based on step emulsification that allows for reliable generation of droplets of different sizes. Until now, sizes of droplets generated with step emulsification were hard-wired into the…
We developed and experimentally verified an analytical model to describe diffusion of oligonucleotides from stable hydrogel beads. The synthesized alginate beads are Fe3+-cross-linked as well as polyelectrolyte-doped for uniformity and…
Place a droplet of mineral oil on water and the oil will spread to cover the water surface in a thin film -- a phenomenon familiar to many, owing to the rainbow-faced puddles left behind leaking buses on rainy days. In this paper we study…
Electrohydrodynamic (EHD) generation, a commonly used method in BioMEMS, plays a significant role in the pulsed-release drug delivery system for a decade. In this paper, an EHD based drug delivery system is well designed, which can be used…
The mechanical properties of biological fluids can serve as early indicators of disease, offering valuable insights into complex physiological and pathological processes. However, the existing technologies can hardly support high throughput…
Effective mixing is essential for biochemical reactions. In droplet-based microfluidics, immediate mixing of substances upon contact in the droplet formation stage can greatly enhance the uniformity of chemical reactions. Furthermore, it…
In this work, we used a coupled level set and volume of fluid (CLSVOF) computational method for studying the generation of microdroplets in a two dimensional circular co-flow microfluidic device. The fundamental understanding of shear…
Oils and fragrances can be encapsulated by using composite shells of silica nanoparticles, polymer and surfactant (potassium oleate). The template for the creation of the core-shell structure is a particle stabilized (Pickering) emulsion.…
A way forward for high throughput fabrication of microcapsules with uniform size and mechanical properties was reported irrespective of the kinetic process of shell assembly. Microcapsules were produced using lab-scale emulsification…
Here, we trap and control the position of droplets to study their dynamics using hydrodynamic forces alone without an external field. The hydrodynamic trap is adapted from a previously implemented Stokes trap by incorporating a…
Micro and nanodroplets have many important applications such as in drug delivery, liquid-liquid extraction, nanomaterial synthesis and cosmetics. A commonly used method to generate a large number of micro or nanodroplets in one simple step…
Droplet migration in a Hele--Shaw cell is a fundamental multiphase flow problem which is crucial for many microfluidics applications. We focus on the regime at low capillary number and three-dimensional direct numerical simulations are…
Droplet microfluidics combined with optical detection has become a powerful approach for high-throughput single-cell assays, but these systems often face limited sensitivity and signal heterogeneity due to optical and geometrical…