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The field of computational pathology has been transformed with recent advances in foundation models that encode histopathology region-of-interests (ROIs) into versatile and transferable feature representations via self-supervised learning…

The package mvlearnR and accompanying Shiny App is intended for integrating data from multiple sources or views or modalities (e.g. genomics, proteomics, clinical and demographic data). Most existing software packages for multiview learning…

Genomics · Quantitative Biology 2023-11-29 Elise F. Palzer , Sandra E. Safo

Deep learning has achieved great success in a wide spectrum of multimedia applications such as image classification, natural language processing and multimodal data analysis. Recent years have seen the development of many deep learning…

Machine Learning · Computer Science 2021-08-06 Naili Xing , Sai Ho Yeung , Chenghao Cai , Teck Khim Ng , Wei Wang , Kaiyuan Yang , Nan Yang , Meihui Zhang , Gang Chen , Beng Chin Ooi

Supervised deep learning methods have achieved considerable success in medical image analysis, owing to the availability of large-scale and well-annotated datasets. However, creating such datasets for whole slide images (WSIs) in…

Computer Vision and Pattern Recognition · Computer Science 2024-06-10 Hao Wang , Euijoon Ahn , Jinman Kim

Colorectal diseases, including inflammatory conditions and neoplasms, require quick, accurate care to be effectively treated. Traditional diagnostic pipelines require extensive preparation and rely on separate, individual evaluations on…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Krithik Ramesh , Ritvik Koneru

Diffusion-based large language models (dLLMs) have emerged as a promising alternative to autoregressive (AR) LLMs, leveraging denoising-based generation to enable inherent parallelism. Even more and more open-sourced dLLM models emerge, yet…

Histopathological analysis of Whole Slide Images (WSIs) has seen a surge in the utilization of deep learning methods, particularly Convolutional Neural Networks (CNNs). However, CNNs often fall short in capturing the intricate spatial…

Computer Vision and Pattern Recognition · Computer Science 2024-06-24 Siemen Brussee , Giorgio Buzzanca , Anne M. R. Schrader , Jesper Kers

Computational pathology has advanced rapidly in recent years, driven by domain-specific image encoders and growing interest in using vision-language models to answer natural-language questions about diseases. Yet, the core problem behind…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Wentao Huang , Weimin Lyu , Peiliang Lou , Qingqiao Hu , Xiaoling Hu , Shahira Abousamra , Wenchao Han , Ruifeng Guo , Jiawei Zhou , Chao Chen , Chen Wang

Digital pathology has advanced significantly over the last decade, with Whole Slide Images (WSIs) encompassing vast amounts of data essential for accurate disease diagnosis. High-resolution WSIs are essential for precise diagnosis but…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Xuan Xu , Saarthak Kapse , Prateek Prasanna

The field of computational pathology has recently seen rapid advances driven by the development of modern vision foundation models (FMs), typically trained on vast collections of pathology images. Recent studies demonstrate that increasing…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Mikhail Karasikov , Joost van Doorn , Nicolas Känzig , Melis Erdal Cesur , Hugo Mark Horlings , Robert Berke , Fei Tang , Sebastian Otálora

The computer-aided analysis of medical scans is a longstanding goal in the medical imaging field. Currently, deep learning has became a dominant methodology for supporting pathologists and radiologist. Deep learning algorithms have been…

Machine Learning · Computer Science 2017-12-06 Jakub M. Tomczak , Maximilian Ilse , Max Welling

The use of artificial intelligence to enable precision medicine and decision support systems through the analysis of pathology images has the potential to revolutionize the diagnosis and treatment of cancer. Such applications will depend on…

With the development of computer-aided diagnosis (CAD) and image scanning technology, Whole-slide Image (WSI) scanners are widely used in the field of pathological diagnosis. Therefore, WSI analysis has become the key to modern digital…

Computer Vision and Pattern Recognition · Computer Science 2021-02-23 Chen Li , Xintong Li , Md Rahaman , Xiaoyan Li , Hongzan Sun , Hong Zhang , Yong Zhang , Xiaoqi Li , Jian Wu , Yudong Yao , Marcin Grzegorzek

Performing diagnosis or exploratory analysis during the training of deep learning models is challenging but often necessary for making a sequence of decisions guided by the incremental observations. Currently available systems for this…

Machine Learning · Computer Science 2020-01-08 Shital Shah , Roland Fernandez , Steven Drucker

Recent studies have made significant progress in developing large language models (LLMs) in the medical domain, which can answer expert-level questions and demonstrate the potential to assist clinicians in real-world clinical scenarios.…

Computation and Language · Computer Science 2025-04-18 Sangwook Kim , Soonyoung Lee , Jongseong Jang

Histopathology remains the gold standard for diagnosis of various cancers. Recent advances in computer vision, specifically deep learning, have facilitated the analysis of histopathology images for various tasks, including immune cell…

Quantitative Methods · Quantitative Biology 2023-11-02 Jakub R. Kaczmarzyk , Tahsin M. Kurc , Shahira Abousamra , Rajarsi Gupta , Joel H. Saltz , Peter K. Koo

Digital pathology archives increasingly contain multiple whole-slide images (WSIs) per case, capturing spatially distinct tumour regions and reflecting intrinsic morphological heterogeneity. However, most existing approaches rely on a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Zahra Rahimi Afzal , Wataru Uegami , Saghir Alfasly , Saba Yasir , Judy C. Boughey , Matthew P. Goetz , Krishna R. Kalari , H. R. Tizhoosh

Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…

Deep neural networks (DNNs) have exhibited remarkable success in the field of histopathology image analysis. On the other hand, the contemporary trend of employing large models and extensive datasets has underscored the significance of…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Cong Cong , Shiyu Xuan , Sidong Liu , Maurice Pagnucco , Shiliang Zhang , Yang Song

Quantitative Susceptibility Mapping (QSM) dipole inversion is an ill-posed inverse problem for quantifying magnetic susceptibility distributions from MRI tissue phases. While supervised deep learning methods have shown success in specific…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Zhuang Xiong , Wei Jiang , Yang Gao , Feng Liu , Hongfu Sun