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Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

InferPy is a Python package for probabilistic modeling with deep neural networks. It defines a user-friendly API that trades-off model complexity with ease of use, unlike other libraries whose focus is on dealing with very general…

Machine Learning · Computer Science 2020-02-13 Javier Cózar , Rafael Cabañas , Antonio Salmerón , Andrés R. Masegosa

Eisen is an open source python package making the implementation of deep learning methods easy. It is specifically tailored to medical image analysis and computer vision tasks, but its flexibility allows extension to any application. Eisen…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Frank Mancolo

In the field of computational histopathology, both whole slide images (WSIs) and diagnostic captions provide valuable insights for making diagnostic decisions. However, aligning WSIs with diagnostic captions presents a significant…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Qifeng Zhou , Wenliang Zhong , Yuzhi Guo , Michael Xiao , Hehuan Ma , Junzhou Huang

Software frameworks for neural networks play a key role in the development and application of deep learning methods. In this paper, we introduce the Chainer framework, which intends to provide a flexible, intuitive, and high performance…

Hematoxylin- and eosin (H&E) stained whole-slide images (WSIs) are the foundation of diagnosis of cancer. In recent years, development of deep learning-based methods in computational pathology enabled the prediction of biomarkers directly…

Presenting whole slide images (WSIs) as graph will enable a more efficient and accurate learning framework for cancer diagnosis. Due to the fact that a single WSI consists of billions of pixels and there is a lack of vast annotated datasets…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Milan Aryal , Nasim Yahyasoltani

Difficulty replicating baselines, high computational costs, and required domain expertise create persistent barriers to clinical AI research. To address these challenges, we introduce PyHealth 2.0, an enhanced clinical deep learning toolkit…

Representation learning of pathology whole-slide images (WSIs) has been has primarily relied on weak supervision with Multiple Instance Learning (MIL). However, the slide representations resulting from this approach are highly tailored to…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Andrew H. Song , Richard J. Chen , Tong Ding , Drew F. K. Williamson , Guillaume Jaume , Faisal Mahmood

Recent advancements in digital pathology have led to the development of numerous foundational models that utilize self-supervised learning on patches extracted from gigapixel whole slide images (WSIs). While this approach leverages vast…

Machine Learning · Computer Science 2024-08-23 Juseung Yun , Yi Hu , Jinhyung Kim , Jongseong Jang , Soonyoung Lee

Pathological image analysis is a crucial field in computer-aided diagnosis, where deep learning is widely applied. Transfer learning using pre-trained models initialized on natural images has effectively improved the downstream pathological…

Image and Video Processing · Electrical Eng. & Systems 2023-10-30 Nan Ying , Yanli Lei , Tianyi Zhang , Shangqing Lyu , Chunhui Li , Sicheng Chen , Zeyu Liu , Yu Zhao , Guanglei Zhang

In this paper, we introduce SciANN, a Python package for scientific computing and physics-informed deep learning using artificial neural networks. SciANN uses the widely used deep-learning packages Tensorflow and Keras to build deep neural…

Other Computer Science · Computer Science 2020-12-30 Ehsan Haghighat , Ruben Juanes

Whole-slide image visual question answering (WSI-VQA) frames pathology as an extreme-context search problem: to answer a free-form clinical query, a system must first navigate a gigapixel slide under a strict inspection budget to locate…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Chunze Yang , Qidong Liu , Wenjie Zhao , Yue Tang , Jiusong Ge , Di Zhang , Jiashuai Liu , Lei Wu , Junbo Lu , Ni Zhang , Xian Wu , Zeyu Gao , Chen Li

Histology slide digitization is becoming essential for telepathology (remote consultation), knowledge sharing (education), and using the state-of-the-art artificial intelligence algorithms (augmented/automated end-to-end clinical…

Image and Video Processing · Electrical Eng. & Systems 2024-05-15 Talat Zehra , Joseph Marino , Wendy Wang , Grigoriy Frantsuzov , Saad Nadeem

Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song

Histopathology tissue analysis is considered the gold standard in cancer diagnosis and prognosis. Given the large size of these images and the increase in the number of potential cancer cases, an automated solution as an aid to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Mahendra Khened , Avinash Kori , Haran Rajkumar , Balaji Srinivasan , Ganapathy Krishnamurthi

Digital pathology and the integration of artificial intelligence (AI) models have revolutionized histopathology, opening new opportunities. With the increasing availability of Whole Slide Images (WSIs), there's a growing demand for…

Image and Video Processing · Electrical Eng. & Systems 2024-04-30 Areej Alsaafin , Peyman Nejat , Abubakr Shafique , Jibran Khan , Saghir Alfasly , Ghazal Alabtah , H. R. Tizhoosh

The annotation of large scale histopathology image datasets remains a major bottleneck in developing robust deep learning models for clinically relevant tasks, such as mitotic figure classification. Folder-based annotation workflows are…

Histopathology, the microscopic study of diseased tissue, is increasingly digitized, enabling improved visualization and streamlined workflows. An important task in histopathology is the segmentation of cells and glands, essential for…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Philipp Endres , Valentin Koch , Julia A. Schnabel , Carsten Marr

The lack of well-annotated datasets in computational pathology (CPath) obstructs the application of deep learning techniques for classifying medical images. %Since pathologist time is expensive, dataset curation is intrinsically difficult.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-28 Ryan Zhang , Jiadai Zhu , Stephen Yang , Mahdi S. Hosseini , Angelo Genovese , Lina Chen , Corwyn Rowsell , Savvas Damaskinos , Sonal Varma , Konstantinos N. Plataniotis