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The lack of fine-grained annotations hinders the deployment of automated diagnosis systems, which require human-interpretable justification for their decision process. In this paper, we address the problem of weakly supervised…

Computer Vision and Pattern Recognition · Computer Science 2022-10-10 Constantin Seibold , Jens Kleesiek , Heinz-Peter Schlemmer , Rainer Stiefelhagen

In recent years, deep learning has become a breakthrough technique in assisting medical image diagnosis. Supervised learning using convolutional neural networks (CNN) provides state-of-the-art performance and has served as a benchmark for…

Image and Video Processing · Electrical Eng. & Systems 2023-06-30 Tao Wang , Xinlin Zhang , Yuanbo Zhou , Junlin Lan , Tao Tan , Min Du , Qinquan Gao , Tong Tong

Content-based medical image retrieval is an important diagnostic tool that improves the explainability of computer-aided diagnosis systems and provides decision making support to healthcare professionals. Medical imaging data, such as…

Computer Vision and Pattern Recognition · Computer Science 2022-11-23 Yunyan Xing , Benjamin J. Meyer , Mehrtash Harandi , Tom Drummond , Zongyuan Ge

Multiple instance learning (MIL) is a robust paradigm for whole-slide pathological image (WSI) analysis, processing gigapixel-resolution images with slide-level labels. As pioneering efforts, attention-based MIL (ABMIL) and its variants are…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Linghan Cai , Shenjin Huang , Ye Zhang , Jinpeng Lu , Yongbing Zhang

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

We present a weakly supervised deep learning model for classifying thoracic diseases and identifying abnormalities in chest radiography. In this work, instead of learning from medical imaging data with region-level annotations, our model…

Computer Vision and Pattern Recognition · Computer Science 2018-11-07 Bo Zhou , Yuemeng Li , Jiangcong Wang

When reading images, radiologists generate text reports describing the findings therein. Current state-of-the-art computer-aided diagnosis tools utilize a fixed set of predefined categories automatically extracted from these medical reports…

Computer Vision and Pattern Recognition · Computer Science 2022-10-10 Constantin Seibold , Simon Reiß , M. Saquib Sarfraz , Rainer Stiefelhagen , Jens Kleesiek

One of the most challenges in medical imaging is the lack of data and annotated data. It is proven that classical segmentation methods such as U-NET are useful but still limited due to the lack of annotated data. Using a weakly supervised…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Amine Amyar , Romain Modzelewski , Pierre Vera , Vincent Morard , Su Ruan

Deep Convolutional Neural Networks have proven effective in solving the task of semantic segmentation. However, their efficiency heavily relies on the pixel-level annotations that are expensive to get and often require domain expertise,…

Computer Vision and Pattern Recognition · Computer Science 2020-07-03 Ostap Viniavskyi , Mariia Dobko , Oles Dobosevych

Universal Lesion Detection (ULD) in computed tomography (CT) plays an essential role in computer-aided diagnosis. Promising ULD results have been reported by anchor-based detection designs, but they have inherent drawbacks due to the use of…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Peiang Zhao , Han Li , Ruiyang Jin , S. Kevin Zhou

Robust and accurate detection and segmentation of heterogenous tumors appearing in different anatomical organs with supervised methods require large-scale labeled datasets covering all possible types of diseases. Due to the unavailability…

Computer Vision and Pattern Recognition · Computer Science 2023-05-23 Mehdi Astaraki , Francesca De Benetti , Yousef Yeganeh , Iuliana Toma-Dasu , Örjan Smedby , Chunliang Wang , Nassir Navab , Thomas Wendler

The increasing digitization of medical imaging enables machine learning based improvements in detecting, visualizing and segmenting lesions, easing the workload for medical experts. However, supervised machine learning requires reliable…

Image and Video Processing · Electrical Eng. & Systems 2024-12-03 Maximilian E. Tschuchnig , Michael Gadermayr

The absence of adequately sufficient expert-level tumor annotations hinders the effectiveness of supervised learning based opportunistic cancer screening on medical imaging. Clinical reports (that are rich in descriptive textual details)…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Guangyu Guo , Jiawen Yao , Yingda Xia , Tony C. W. Mok , Zhilin Zheng , Junwei Han , Le Lu , Dingwen Zhang , Jian Zhou , Ling Zhang

Deep learning methods have shown outstanding classification accuracy in medical imaging problems, which is largely attributed to the availability of large-scale datasets manually annotated with clean labels. However, given the high cost of…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Yuanhong Chen , Fengbei Liu , Hu Wang , Chong Wang , Yu Tian , Yuyuan Liu , Gustavo Carneiro

In the cancer diagnosis pipeline, digital pathology plays an instrumental role in the identification, staging, and grading of malignant areas on biopsy tissue specimens. High resolution histology images are subject to high variance in…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Vasileios Magoulianitis , Catherine A. Alexander , C. -C. Jay Kuo

Deep Convolutional Neural Networks have consistently proven to achieve state-of-the-art results on a lot of imaging tasks over the past years' majority of which comprise of high-quality data. However, it is important to work on…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Snigdha Agarwal , Neelam Sinha

Fetal abdominal malformations are serious congenital anomalies that require accurate diagnosis to guide pregnancy management and reduce mortality. Although AI has demonstrated significant potential in medical diagnosis, its application to…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Huanwen Liang , Jingxian Xu , Yuanji Zhang , Yuhao Huang , Yuhan Zhang , Xin Yang , Ran Li , Xuedong Deng , Yanjun Liu , Guowei Tao , Yun Wu , Sheng Zhao , Xinru Gao , Dong Ni

Traditional deep learning models often lack annotated data, especially in cross-domain applications such as anomaly detection, which is critical for early disease diagnosis in medicine and defect detection in industry. To address this…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Wahyu Rahmaniar , Kenji Suzuki

Radiography imaging protocols focus on particular body regions, therefore producing images of great similarity and yielding recurrent anatomical structures across patients. Exploiting this structured information could potentially ease the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Tiange Xiang , Yixiao Zhang , Yongyi Lu , Alan Yuille , Chaoyi Zhang , Weidong Cai , Zongwei Zhou

Multiple-instance learning (MIL) is an attractive approach for digital pathology applications as it reduces the costs related to data collection and labelling. However, it is not clear how sensitive MIL is to clinically realistic domain…

Computer Vision and Pattern Recognition · Computer Science 2024-05-17 Milda Pocevičiūtė , Gabriel Eilertsen , Stina Garvin , Claes Lundström