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We propose a new multi-scale molecular dynamics simulation method which can achieve high accuracy and high sampling efficiency simultaneously without aforehand knowledge of the coarse grained (CG) potential and test it for a biomolecular…

Biological Physics · Physics 2009-08-05 Wenfei Li , Shoji Takada

Deoxyribonucleic acid (DNA) has shown great promise in enabling computational applications, most notably in the fields of DNA digital data storage and DNA computing. Information is encoded as DNA strands, which will naturally bind in…

Machine Learning · Computer Science 2021-10-22 David Buterez

Machine learning has been widely verified and applied in chemoinformatics, and have achieved outstanding results in the prediction, modification, and optimization of luminescence, magnetism, and electrode materials. Here, we propose a…

Materials Science · Physics 2021-07-07 Zhenyu Chen , Jiahao Li , Yuzhi Xu

Deep clustering as an important branch of unsupervised representation learning focuses on embedding semantically similar samples into the identical feature space. This core demand inspires the exploration of contrastive learning and…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Haifeng Xia , Hai Huang , Zhengming Ding

In single molecule localisation super-resolution microscopy the need for repeated image capture limits the imaging speed, while the size of fluorescence probes limits the possible theoretical localisation resolution. Here, we demonstrated a…

Cotton crops, often called "white gold," face significant production challenges, primarily due to various leaf-affecting diseases. As a major global source of fiber, timely and accurate disease identification is crucial to ensure optimal…

Computer Vision and Pattern Recognition · Computer Science 2025-06-27 Aswini Kumar Patra , Tejashwini Gajurel

Deep ensembles deliver state-of-the-art, reliable uncertainty quantification, but their heavy computational and memory requirements hinder their practical deployments to real applications such as on-device AI. Knowledge distillation…

Machine Learning · Computer Science 2025-10-27 Sehyun Park , Jongjin Lee , Yunseop Shin , Ilsang Ohn , Yongdai Kim

Density functional theory (DFT) is one of the main methods in Quantum Chemistry that offers an attractive trade off between the cost and accuracy of quantum chemical computations. The electron density plays a key role in DFT. In this work,…

Chemical Physics · Physics 2018-09-11 Anton V. Sinitskiy , Vijay S. Pande

Federated Learning (FL) enables collaborative model training across distributed clients without sharing raw data, thereby preserving privacy. However, FL often suffers from significant communication and computational overhead, limiting its…

Machine Learning · Computer Science 2026-04-15 Elouan Colybes , Shirin Salehi , Anke Schmeink

The increasing size and complexity of medical imaging datasets, particularly in 3D formats, present significant barriers to collaborative research and transferability. This study investigates whether the ZFP compression technique can…

Computer Vision and Pattern Recognition · Computer Science 2025-12-18 Shimaa Elbana , Ahmad Kamal , Shahd Ahmed Ali , Ahmad Al-Kabbany

Gaussian processes (GPs) are flexible models that can capture complex structure in large-scale dataset due to their non-parametric nature. However, the usage of GPs in real-world application is limited due to their high computational cost…

Machine Learning · Statistics 2018-11-06 Congzheng Song , Yiming Sun

This paper addresses the problem of quantifying biomarkers in multi-stained tissues, based on color and spatial information. A deep learning based method that can automatically localize and quantify the cells expressing biomarker(s) in a…

Tissues and Organs · Quantitative Biology 2017-01-02 Fahime Sheikhzadeh , Martial Guillaud , Rabab K. Ward

Over the last few decades, artificial intelligence research has made tremendous strides, but it still heavily relies on fixed datasets in stationary environments. Continual learning is a growing field of research that examines how AI…

Computer Vision and Pattern Recognition · Computer Science 2021-08-06 Minha Kim , Shahroz Tariq , Simon S. Woo

Early and accurately detecting faults in rotating machinery is crucial for operation safety of the modern manufacturing system. In this paper, we proposed a novel Deep fault diagnosis (DFD) method for rotating machinery with scarce labeled…

Signal Processing · Electrical Eng. & Systems 2019-07-23 Jing Zhang , Jing Tian , Tao Wen , Xiaohui Yang , Yong Rao , Xiaobin Xu

We propose a highly data-efficient active learning framework for image classification. Our novel framework combines: (1) unsupervised representation learning of a Convolutional Neural Network and (2) the Gaussian Process (GP) method, in…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Heng Hao , Hankyu Moon , Sima Didari , Jae Oh Woo , Patrick Bangert

The rapid evolution of deepfake generation technologies poses critical challenges for detection systems, as non-continual learning methods demand frequent and expensive retraining. We reframe deepfake detection (DFD) as a Continual Learning…

Machine Learning · Computer Science 2025-09-11 Federico Fontana , Anxhelo Diko , Romeo Lanzino , Marco Raoul Marini , Bachir Kaddar , Gian Luca Foresti , Luigi Cinque

The flow matching has rapidly become a dominant paradigm in classical generative modeling, offering an efficient way to interpolate between two complex distributions. We extend this idea to the quantum realm and introduce the Quantum Flow…

Quantum Physics · Physics 2026-02-03 Zidong Cui , Pan Zhang , Ying Tang

We describe a novel cancer diagnostic method based on plasma denaturation profiles obtained by a non-conventional use of Differential Scanning Fluorimetry. We show that 84 glioma patients and 63 healthy controls can be automatically…

Uncertainty quantification in automated image analysis is highly desired in many applications. Typically, machine learning models in classification or segmentation are only developed to provide binary answers; however, quantifying the…

The analysis of microcirculation images has the potential to reveal early signs of life-threatening diseases like sepsis. Quantifying the capillary density and the capillary distribution in microcirculation images can be used as a…

Computer Vision and Pattern Recognition · Computer Science 2022-05-12 Maged Abdalla Helmy Mohamed Abdou , Trung Tuyen Truong , Eric Jul , Paulo Ferreira