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With pervasive applications of medical imaging in health-care, biomedical image segmentation plays a central role in quantitative analysis, clinical diagno- sis, and medical intervention. Since manual anno- tation su ers limited…

Computer Vision and Pattern Recognition · Computer Science 2018-03-14 Xiaowei Xu , Qing Lu , Yu Hu , Lin Yang , Sharon Hu , Danny Chen , Yiyu Shi

Aggregation-based assays, using micro- and nano-particles have been widely accepted as an efficient and cost-effective bio-sensing tool, particularly in microbiology, where particle clustering events are used as a metric to infer the…

Instrumentation and Detectors · Physics 2018-12-31 Yichen Wu , Aniruddha Ray , Qingshan Wei , Alborz Feizi , Xin Tong , Eva Chen , Yi Luo , Aydogan Ozcan

General Defocusing Particle Tracking (GDPT) is a single-camera, three-dimensional particle tracking method that determines the particle depth positions from the defocusing patterns of the corresponding particle images. GDPT relies on a…

Fluid Dynamics · Physics 2020-05-05 Rune Barnkob , Massimiliano Rossi

In this paper, we propose a deep-learning-based approach to a class of multiscale problems. THe Generalized Multiscale Finite Element Method (GMsFEM) has been proven successful as a model reduction technique of flow problems in…

Numerical Analysis · Mathematics 2018-10-30 Min Wang , Siu Wun Cheung , Eric T. Chung , Yalchin Efendiev , Wing Tat Leung , Yating Wang

The full understanding of cellular functions requires information about protein numbers for various biomolecular assemblies and their dynamics, which can be partly accessed by super-resolution fluorescence microscopy. Yet, many protein…

Biological Physics · Physics 2020-06-17 Kristin S. Grußmayer , Klaus Yserentant , Dirk-Peter Herten

In multiphase flow systems, classifying flow patterns is crucial to optimize fluid dynamics and enhance system efficiency. Current industrial methods and scientific laboratories mainly depend on techniques such as flow visualization using…

Machine Learning · Computer Science 2025-02-27 Nian Ran , Fayez M. Al-Alweet , Richard Allmendinger , Ahmad Almakhlafi

Using the raw data from consumer-level RGB-D cameras as input, we propose a deep-learning based approach to efficiently generate RGB-D images with completed information in high resolution. To process the input images in low resolution with…

Computer Vision and Pattern Recognition · Computer Science 2020-06-15 Chuhua Xian , Dongjiu Zhang , Chengkai Dai , Charlie C. L. Wang

Deep Gaussian processes (DGP) have appealing Bayesian properties, can handle variable-sized data, and learn deep features. Their limitation is that they do not scale well with the size of the data. Existing approaches address this using a…

Machine Learning · Computer Science 2019-05-20 Issam H. Laradji , Mark Schmidt , Vladimir Pavlovic , Minyoung Kim

The limits of molecular dynamics (MD) simulations of macromolecules are steadily pushed forward by the relentless developments of computer architectures and algorithms. This explosion in the number and extent (in size and time) of MD…

Diffusion probabilistic models (DPMs) have achieved impressive success in visual generation. While, they suffer from slow inference speed due to iterative sampling. Employing fewer sampling steps is an intuitive solution, but this will also…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Hu Yu , Hao Luo , Fan Wang , Feng Zhao

Transcriptional profiling on microarrays to obtain gene expressions has been used to facilitate cancer diagnosis. We propose a deep generative machine learning architecture (called DeepCancer) that learn features from unlabeled microarray…

Artificial Intelligence · Computer Science 2016-12-14 Rajendra Rana Bhat , Vivek Viswanath , Xiaolin Li

We develop a novel parallel resampling algorithm for fully parallelized particle filters, which is designed with GPUs (graphics processing units) or similar parallel computing devices in mind. With our new algorithm, a full cycle of…

Computation · Statistics 2016-08-17 Kenichiro McAlinn , Teruo Nakatsuma

Image generation using diffusion models have demonstrated outstanding learning capabilities, effectively capturing the full distribution of the training dataset. They are known to generate wide variations in sampled images, albeit with a…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Rahul Shenoy , Zhihong Pan , Kaushik Balakrishnan , Qisen Cheng , Yongmoon Jeon , Heejune Yang , Jaewon Kim

The effectiveness of machine learning algorithms arises from being able to extract useful features from large amounts of data. As model and dataset sizes increase, dataset distillation methods that compress large datasets into significantly…

Machine Learning · Computer Science 2022-01-19 Timothy Nguyen , Roman Novak , Lechao Xiao , Jaehoon Lee

Recent advancements in generalizable novel view synthesis have achieved impressive quality through interpolation between nearby views. However, rendering high-resolution images remains computationally intensive due to the need for dense…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Li Fang , Hao Zhu , Longlong Chen , Fei Hu , Long Ye , Zhan Ma

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Melika Filvantorkaman , Maral Filvan Torkaman

A device capable of performing real time classification of proteins in a clinical setting would allow for inexpensive and rapid disease diagnosis. One such candidate for this technology are nanopore devices. These devices work by measuring…

Machine Learning · Computer Science 2025-09-18 Samuel Tovey , Julian Hoßbach , Sandro Kuppel , Tobias Ensslen , Jan C. Behrends , Christian Holm

Due to its specificity, fluorescence microscopy (FM) has become a quintessential imaging tool in cell biology. However, photobleaching, phototoxicity, and related artifacts continue to limit FM's utility. Recently, it has been shown that…

Biological machine learning is often bottlenecked by a lack of scaled data. One promising route to relieving data bottlenecks is through high throughput screens, which can experimentally test the activity of $10^6-10^{12}$ protein sequences…

Machine Learning · Statistics 2025-10-21 Eli N. Weinstein , Andrei Slabodkin , Mattia G. Gollub , Elizabeth B. Wood

Besides accuracy, the model size of convolutional neural networks (CNN) models is another important factor considering limited hardware resources in practical applications. For example, employing deep neural networks on mobile systems…

Machine Learning · Computer Science 2021-07-05 Huixin Zhan , Wei-Ming Lin , Yongcan Cao