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Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung

Colorectal cancer (CRC) is a leading worldwide cause of cancer-related mortality, and the role of prompt precise detection is of paramount interest in improving patient outcomes. Conventional diagnostic methods such as colonoscopy and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-29 Ovi Sarkar , Md Shafiuzzaman , Md. Faysal Ahamed , Golam Mahmud , Muhammad E. H. Chowdhury

Osteoarthritis is a degenerative condition affecting bones and cartilage, often leading to osteophyte formation, bone density loss, and joint space narrowing. Treatment options to restore normal joint function vary depending on the severity…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Luca Marsilio , Davide Marzorati , Matteo Rossi , Andrea Moglia , Luca Mainardi , Alfonso Manzotti , Pietro Cerveri

Purpose Automated segmentation of anatomical structures in medical image analysis is a prerequisite for autonomous diagnosis as well as various computer and robot aided interventions. Recent methods based on deep convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2020-09-22 Max-Heinrich Laves , Jens Bicker , Lüder A. Kahrs , Tobias Ortmaier

Celiac Disease (CD) is a chronic autoimmune disease that affects the small intestine in genetically predisposed children and adults. Gluten exposure triggers an inflammatory cascade which leads to compromised intestinal barrier function. If…

Image and Video Processing · Electrical Eng. & Systems 2019-10-09 Rasoul Sali , Lubaina Ehsan , Kamran Kowsari , Marium Khan , Christopher A. Moskaluk , Sana Syed , Donald E. Brown

Bone marrow cytology is required to make a hematological diagnosis, influencing critical clinical decision points in hematology. However, bone marrow cytology is tedious, limited to experienced reference centers and associated with high…

Image and Video Processing · Electrical Eng. & Systems 2021-07-09 Rohollah Moosavi Tayebi , Youqing Mu , Taher Dehkharghanian , Catherine Ross , Monalisa Sur , Ronan Foley , Hamid R. Tizhoosh , Clinton JV Campbell

In breast cancer, neoadjuvant chemotherapy (NAC) provides a standard treatment option for patients who have locally advanced cancer and some large operable tumors. A patient will have better prognosis when he has achieved a pathological…

Medical Physics · Physics 2024-11-12 Yongquan Yang , Fengling Li , Yani Wei , Yuanyuan Zhao , Jing Fu , Xiuli Xiao , Hong Bu

In the Gastric Histopathology Image Classification (GHIC) tasks, which are usually weakly supervised learning missions, there is inevitably redundant information in the images. Therefore, designing networks that can focus on effective…

Computer Vision and Pattern Recognition · Computer Science 2021-04-23 Yixin Li , Xinran Wu , Chen Li , Changhao Sun , Md Rahaman , Haoyuan Chen , Yudong Yao , Xiaoyan Li , Yong Zhang , Tao Jiang

Dealing with the application of grading colorectal cancer images, this work proposes a 3 step pipeline for prediction of cancer levels from a histopathology image. The overall model performs better compared to other state of the art methods…

Computer Vision and Pattern Recognition · Computer Science 2020-10-05 Franziska Lippoldt

There exists unexplained diverse variation within the predefined colon cancer stages using only features either from genomics or histopathological whole slide images as prognostic factors. Unraveling this variation will bring about improved…

Quantitative Methods · Quantitative Biology 2022-12-15 Olalekan Ogundipe , Zeyneb Kurt , Wai Lok Woo

The Intensive Care Unit (ICU) is one of the most important parts of a hospital, which admits critically ill patients and provides continuous monitoring and treatment. Various patient outcome prediction methods have been attempted to assist…

Machine Learning · Computer Science 2023-10-24 Yuxi Liu , Zhenhao Zhang , Shaowen Qin , Flora D. Salim , Antonio Jimeno Yepes , Jun Shen , Jiang Bian

Patient-level diagnosis of severity in ulcerative colitis (UC) is common in real clinical settings, where the most severe score in a patient is recorded. However, previous UC classification methods (i.e., image-level estimation) mainly…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Kaito Shiku , Kazuya Nishimura , Daiki Suehiro , Kiyohito Tanaka , Ryoma Bise

Objective: To systematically evaluate the value of endocytoscopy (ECS) in the diagnosis of early esophageal cancer (EC). Methods: Pubmed, Ovid and EMbase databases were searched to collect diagnostic tests of ECS assisted diagnosis of early…

Tissues and Organs · Quantitative Biology 2023-01-10 Lu Wang , Bofu Tang , Feifei Liu , Zhenyu Jiang , Xianmei Meng

To develop and validate a fully automated, deep-learning pipeline for measuring glenoid bone loss on 3D CT scans using linear-based, en-face view, and best-circle method. Shoulder CT scans of 81 patients were retrospectively collected…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Zhonghao Liu , Hanxue Gu , Qihang Li , Michael Fox , Jay M. Levin , Maciej A. Mazurowski , Brian C. Lau

Introduction: Timely care in a specialised neuro-intensive therapy unit (ITU) reduces mortality and hospital stays, with planned admissions being safer than unplanned ones. However, post-operative care decisions remain subjective. This…

In radiotherapy planning, manual contouring is labor-intensive and time-consuming. Accurate and robust automated segmentation models improve the efficiency and treatment outcome. We aim to develop a novel hybrid deep learning approach,…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Zhuangzhuang Zhang , Tianyu Zhao , Hiram Gay , Weixiong Zhang , Baozhou Sun

The electronic health record (EHR) contains a large amount of multi-dimensional and unstructured clinical data of significant operational and research value. Distinguished from previous studies, our approach embraces a double-annotated…

Computation and Language · Computer Science 2017-08-24 Bonggun Shin , Falgun H. Chokshi , Timothy Lee , Jinho D. Choi

Inflammatory bowel disease (IBD) involves chronic inflammation of the digestive tract, with treatment options often burdened by adverse effects. Identifying biomarkers for personalized treatment is crucial. While immune cells play a key…

Image and Video Processing · Electrical Eng. & Systems 2025-04-15 Ruiwen Ding , Lin Li , Rajath Soans , Tosha Shah , Radha Krishnan , Marc Alexander Sze , Sasha Lukyanov , Yash Deshpande , Antong Chen

Histological classification of colorectal polyps plays a critical role in both screening for colorectal cancer and care of affected patients. An accurate and automated algorithm for the classification of colorectal polyps on digitized…

This paper presents a novel approach to noninvasive hyperglycemia monitoring utilizing electrocardiograms (ECG) from an extensive database comprising 1119 subjects. Previous research on hyperglycemia or glucose detection using ECG has been…

Signal Processing · Electrical Eng. & Systems 2024-03-13 MohammadReza Hosseinzadehketilateh , Banafsheh Adami , Nima Karimian