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Coronary artery calcium (CAC) is a significant marker of atherosclerosis and cardiovascular events. In this work we present a system for the automatic quantification of calcium score in ECG-triggered non-contrast enhanced cardiac computed…

Computer Vision and Pattern Recognition · Computer Science 2017-10-10 G. Santini , D. Della Latta , N. Martini , G. Valvano , A. Gori , A. Ripoli , C. L. Susini , L. Landini , D. Chiappino

Cardiovascular disease (CVD) remains the foremost cause of mortality worldwide, underscoring the urgent need for intelligent and data-driven diagnostic tools. Traditional predictive models often struggle to generalize across heterogeneous…

Artificial Intelligence · Computer Science 2026-01-27 Rajan Das Gupta , Xiaobin Wu , Xun Liu , Jiaqi He

Coronary artery calcification (CAC) is a strong and independent predictor of cardiovascular disease (CVD). However, manual assessment of CAC often requires radiological expertise, time, and invasive imaging techniques. The purpose of this…

Computer Vision and Pattern Recognition · Computer Science 2024-02-16 Andrew M. Nguyen , Jianfei Liu , Tejas Sudharshan Mathai , Peter C. Grayson , Ronald M. Summers

Cardiovascular disease causes high rates of mortality worldwide. Coronary artery calcium (CAC) scoring is a powerful tool to stratify the risk of atherosclerotic cardiovascular disease. Current scoring practices require time-intensive…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Lachlan Nguyen , Aidan Cousins , Arcot Sowmya , Hugh Dixson , Sonit Singh

Coronary artery calcium (CAC) is biomarker of advanced subclinical coronary artery disease and predicts myocardial infarction and death prior to age 60 years. The slice-wise manual delineation has been regarded as the gold standard of…

Computer Vision and Pattern Recognition · Computer Science 2018-11-13 Yuankai Huo , James G. Terry , Jiachen Wang , Vishwesh Nath , Camilo Bermudez , Shunxing Bao , Prasanna Parvathaneni , J. Jeffery Carr , Bennett A. Landman

Cardiac diseases are among the leading causes of morbidity and mortality worldwide, which requires accurate and timely diagnostic strategies. In this study, we introduce an innovative approach that combines deep learning image registration…

Machine Learning · Computer Science 2025-07-09 Comte Valentin , Gemma Piella , Mario Ceresa , Miguel A. Gonzalez Ballester

Cardiovascular diseases (CVDs) are the most common cause of death worldwide. Invasive x-ray coronary angiography (ICA) is one of the most important imaging modalities for the diagnosis of CVDs. ICA typically acquires only two 2D…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Yiying Wang , Abhirup Banerjee , Robin P. Choudhury , Vicente Grau

Background: Coronary Artery Disease (CAD) is one of the leading causes of death worldwide. Invasive Coronary Angiography (ICA), regarded as the gold standard for CAD diagnosis, necessitates precise vessel segmentation and stenosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Nan Mu , Ruiqi Song , Zhihui Xu , Jingfeng Jiang , Chen Zhao

Automated noninvasive cardiac diagnosis plays a critical role in the early detection of cardiac disorders and cost-effective clinical management. Automated diagnosis involves the automated segmentation and analysis of cardiac images.…

Image and Video Processing · Electrical Eng. & Systems 2025-04-21 Racheal Mukisa , Arvind K. Bansal

Coronary Artery Disease (CAD) remains a leading cause of morbidity and mortality worldwide. Early detection is critical to recover patient outcomes and decrease healthcare costs. In recent years, machine learning (ML) advancements have…

Artificial Intelligence · Computer Science 2026-03-10 Karan Kumar Singh , Nikita Gajbhiye , Gouri Sankar Mishra

Automatic labeling of coronary arteries is an essential task in the practical diagnosis process of cardiovascular diseases. For experienced radiologists, the anatomically predetermined connections are important for labeling the artery…

Image and Video Processing · Electrical Eng. & Systems 2023-07-25 Zhixing Zhang , Ziwei Zhao , Dong Wang , Shishuang Zhao , Yuhang Liu , Jia Liu , Liwei Wang

Coronary artery disease (CAD) remains a leading cause of mortality worldwide, requiring accurate segmentation and stenosis detection using Coronary Computed Tomography angiography (CCTA). Existing methods struggle with challenges such as…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Ni Yao , Xiangyu Liu , Danyang Sun , Chuang Han , Yanting Li , Jiaofen Nan , Chengyang Li , Fubao Zhu , Weihua Zhou , Chen Zhao

Coronary angiography is considered to be a safe tool for the evaluation of coronary artery disease and perform in approximately 12 million patients each year worldwide. [1] In most cases, angiograms are manually analyzed by a cardiologist.…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Stanislav Filippov , Arsenii Moiseev , Andronenko Andrey

Cardio-cerebrovascular diseases are the leading causes of mortality worldwide, whose accurate blood vessel segmentation is significant for both scientific research and clinical usage. However, segmenting cardio-cerebrovascular structures…

Image and Video Processing · Electrical Eng. & Systems 2024-04-03 Nazik Elsayed , Yousuf Babiker M. Osman , Cheng Li , Jiong Zhang , Shanshan Wang

Background: Coronary angiography (CAG) is a cornerstone imaging modality for assessing coronary artery disease and guiding interventional treatment decisions. However, in real-world clinical settings, angiographic images are often…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Jingsong Xia , Siqi Wang

Coronary CT angiography (CCTA) has established its role as a non-invasive modality for the diagnosis of coronary artery disease (CAD). The CAD-Reporting and Data System (CAD-RADS) has been developed to standardize communication and aid in…

The Intensive Care Unit (ICU) is one of the most important parts of a hospital, which admits critically ill patients and provides continuous monitoring and treatment. Various patient outcome prediction methods have been attempted to assist…

Machine Learning · Computer Science 2023-10-24 Yuxi Liu , Zhenhao Zhang , Shaowen Qin , Flora D. Salim , Antonio Jimeno Yepes , Jun Shen , Jiang Bian

Heart failure is a leading cause of global mortality, necessitating improved diagnostic strategies. Classical machine learning models struggle with challenges such as high-dimensional data, class imbalances, poor feature representations,…

Machine Learning · Computer Science 2025-08-19 Md Abrar Jahin , Md. Akmol Masud , M. F. Mridha , Zeyar Aung , Nilanjan Dey

In stable coronary artery disease (CAD), reduction in mortality and/or myocardial infarction with revascularization over medical therapy has not been reliably achieved. Coronary arteries are usually extracted to perform stenosis detection.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Chen Zhao , Haipeng Tang , Daniel McGonigle , Zhuo He , Chaoyang Zhang , Yu-Ping Wang , Hong-Wen Deng , Robert Bober , Weihua Zhou

Alterations in the geometry and function of the heart define well-established causes of cardiovascular disease. However, current approaches to the diagnosis of cardiovascular diseases often rely on subjective human assessment as well as…

Computer Vision and Pattern Recognition · Computer Science 2018-07-19 Carlo Biffi , Ozan Oktay , Giacomo Tarroni , Wenjia Bai , Antonio De Marvao , Georgia Doumou , Martin Rajchl , Reem Bedair , Sanjay Prasad , Stuart Cook , Declan O'Regan , Daniel Rueckert