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Despite extensive research during the last decades, coronary artery disease (CAD) remains the number one cause of death, responsible for near 50% of global mortality. A main reason for this is that CAD has a complex inheritance and etiology…

Quantitative Methods · Quantitative Biology 2016-05-12 Hassan Foroughi Asl

Globally, Coronary Heart Disease (CHD) is one of the main causes of death. Early detection of CHD can improve patient outcomes and reduce mortality rates. We propose a novel framework for predicting the presence of CHD using a combination…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 R. Selvaraj , T. Satheesh , V. Suresh , V. Yathavaraj

Cardiovascular diseases (CVDs) are the leading cause of death worldwide, accounting for approximately 17.9 million deaths each year. Early detection is critical, creating a demand for accurate and inexpensive pre-screening methods. Deep…

Sound · Computer Science 2025-12-09 Milan Marocchi , Matthew Fynn , Kayapanda Mandana , Yue Rong

Coronary artery calcification (CAC) is a strong predictor of cardiovascular risk but remains underutilized in clinical routine thoracic imaging due to the need for dedicated imaging protocols and manual annotation. We present DeepCAC2, a…

Image and Video Processing · Electrical Eng. & Systems 2026-03-27 Leonard Nürnberg , Simon Bernatz , Borek Foldyna , Michael T. Lu , Andrey Fedorov , Hugo JWL Aerts

Coronary arteries and their branches supply blood to myocardium. The obstruction of coronary arteries results in significant loss of myocardium, called acute myocardial infarction, and the number one cause of death globally. Hence,…

Computational Geometry · Computer Science 2017-08-31 Jehyun Chaa , Joonghyun Ryub , Jin-Ho Choi , Deok-Soo Kim

Assessing coronary artery plaque segments in coronary CT angiography scans is an important task to improve patient management and clinical outcomes, as it can help to decide whether invasive investigation and treatment are necessary. In…

Myocardial infarction (MI) is a leading cause of death, and its adverse outcomes are urgent to predict. Yet ECG-based prognostic models underperform because deep learning requires large, labelled datasets, which are scarce in medicine.…

Myocardial infarction is the leading cause of death worldwide. In this paper, we design domain-inspired neural network models to detect myocardial infarction. First, we study the contribution of various leads. This systematic analysis,…

Machine Learning · Computer Science 2021-01-27 Arjun Gupta , E. A. Huerta , Zhizhen Zhao , Issam Moussa

The segmentation of coronary arteries by convolutional neural network is promising yet requires a large amount of labor-intensive manual annotations. Transferring knowledge from retinal vessels in widely-available public labeled fundus…

Image and Video Processing · Electrical Eng. & Systems 2021-05-07 Jingyang Zhang , Ran Gu , Guotai Wang , Hongzhi Xie , Lixu Gu

Significant intra-observer and inter-observer variability in the interpretation of coronary angiograms are reported. This variability is in part due to the common practices that rely on performing visual inspections by specialists (e.g.,…

Quantitative Methods · Quantitative Biology 2020-02-27 Babak Ravandi , Arash Ravandi

Many visualizations have been developed for explainable AI (XAI), but they often require further reasoning by users to interpret. Investigating XAI for high-stakes medical diagnosis, we propose improving domain alignment with diagrammatic…

Artificial Intelligence · Computer Science 2025-02-27 Brian Y. Lim , Joseph P. Cahaly , Chester Y. F. Sng , Adam Chew

Background: Cardiovascular diseases (CVDs) are the leading cause of death globally. The use of artificial intelligence (AI) methods - in particular, deep learning (DL) - has been on the rise lately for the analysis of different CVD-related…

Atrial fibrillation (AF) is the most common cardiac arrhythmia, which is clinically identified with irregular and rapid heartbeat rhythm. AF puts a patient at risk of forming blood clots, which can eventually lead to heart failure, stroke,…

Signal Processing · Electrical Eng. & Systems 2023-06-28 Jianxin Xie , Stavros Stavrakis , Bing Yao

Precise localization of coronary arteries in Computed Tomography (CT) scans is critical from the perspective of medical assessment of coronary artery disease. Although various methods exist that offer high-quality segmentation of coronary…

Image and Video Processing · Electrical Eng. & Systems 2024-10-27 Mariusz Bujny , Katarzyna Jesionek , Jakub Nalepa , Karol Miszalski-Jamka , Katarzyna Widawka-Żak , Sabina Wolny , Marcin Kostur

Coronary angiography remains the gold standard for diagnosis of coronary artery disease, the most common cause of death worldwide. While this procedure is performed more than 2 million times annually, there remain few methods for fast and…

Image and Video Processing · Electrical Eng. & Systems 2023-10-25 Tom Liu , Hui Lin , Aggelos K. Katsaggelos , Adrienne Kline

Cardiovascular diseases (CVDs) are the leading cause of global mortality, necessitating accessible and accurate diagnostic tools. While cardiac magnetic resonance imaging (CMR) provides gold-standard insights into cardiac structure and…

Graph Neural Networks (GNNs) have emerged as a prominent class of data-driven methods for molecular property prediction. However, a key limitation of typical GNN models is their inability to quantify uncertainties in the predictions. This…

Machine Learning · Computer Science 2024-07-02 Shengli Jiang , Shiyi Qin , Reid C. Van Lehn , Prasanna Balaprakash , Victor M. Zavala

A large number of people suffer from life-threatening cardiac abnormalities, and electrocardiogram (ECG) analysis is beneficial to determining whether an individual is at risk of such abnormalities. Automatic ECG classification methods,…

Artificial Intelligence · Computer Science 2022-06-23 Yuexin Bian , Jintai Chen , Xiaojun Chen , Xiaoxian Yang , Danny Z. Chen , JIan Wu

In the field of heart disease classification, two primary obstacles arise. Firstly, existing Electrocardiogram (ECG) datasets consistently demonstrate imbalances and biases across various modalities. Secondly, these time-series data consist…

Machine Learning · Computer Science 2024-07-31 Thao Hoang , Linh Nguyen , Khoi Do , Duong Nguyen , Viet Dung Nguyen

Uncertainty of labels in clinical data resulting from intra-observer variability can have direct impact on the reliability of assessments made by deep neural networks. In this paper, we propose a method for modelling such uncertainty in the…

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