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Artificial intelligence (AI) has transformed digital pathology by enabling biomarker prediction from high-resolution whole-slide images (WSIs). However, current methods are computationally inefficient, processing thousands of redundant…

Video endoscopy represents a major advance in the investigation of gastrointestinal diseases. Reviewing endoscopy videos often involves frequent adjustments and reorientations to piece together a complete view, which can be both…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Juming Xiong , Muyang Li , Ruining Deng , Tianyuan Yao , Shunxing Bao , Regina N Tyree , Girish Hiremath , Yuankai Huo

Esophageal cancer is one of the most common types of cancer worldwide and ranks sixth in cancer-related mortality. Accurate computer-assisted diagnosis of cancer progression can help physicians effectively customize personalized treatment…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Chengyu Wu , Chengkai Wang , Yaqi Wang , Huiyu Zhou , Yatao Zhang , Qifeng Wang , Shuai Wang

Objective: To systematically evaluate the value of endocytoscopy (ECS) in the diagnosis of early esophageal cancer (EC). Methods: Pubmed, Ovid and EMbase databases were searched to collect diagnostic tests of ECS assisted diagnosis of early…

Tissues and Organs · Quantitative Biology 2023-01-10 Lu Wang , Bofu Tang , Feifei Liu , Zhenyu Jiang , Xianmei Meng

In this work, we have concentrated our efforts on the interpretability of classification results coming from a fully convolutional neural network. Motivated by the classification of oesophageal tissue for real-time detection of early…

Estimating disease severity from endoscopic images is essential in assessing ulcerative colitis, where the Mayo Endoscopic Subscore (MES) is widely used to grade inflammation. However, MES classification remains challenging due to label…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Zeynep Ozdemir , Hacer Yalim Keles , Omer Ozgur Tanriover

Oral Squamous Cell Carcinoma (OSCC) is a common type of cancer of the oral epithelium. Despite their high impact on mortality, sufficient screening methods for early diagnosis of OSCC often lack accuracy and thus OSCCs are mostly diagnosed…

Computer Vision and Pattern Recognition · Computer Science 2017-09-21 Marc Aubreville , Christian Knipfer , Nicolai Oetter , Christian Jaremenko , Erik Rodner , Joachim Denzler , Christopher Bohr , Helmut Neumann , Florian Stelzle , Andreas Maier

Diagnosing esophageal motility disorders pose significant challenges due to the complexity of high-resolution impedance manometry (HRIM) data and variability in clinical interpretation. This work explores the feasibility of a multimodal…

Machine Learning · Computer Science 2026-05-14 Alexander Geiger , Lars Wagner , Daniel Rueckert , Alois Knoll , Dirk Wilhelm , Alissa Jell

High-frequency oscillations (HFOs) in intracranial Electroencephalography (iEEG) are critical biomarkers for localizing the epileptogenic zone in epilepsy treatment. However, traditional rule-based detectors for HFOs suffer from…

Computational Engineering, Finance, and Science · Computer Science 2025-07-22 Yipeng Zhang , Yuanyi Ding , Chenda Duan , Atsuro Daida , Hiroki Nariai , Vwani Roychowdhury

Organoids, sophisticated in vitro models of human tissues, are crucial for medical research due to their ability to simulate organ functions and assess drug responses accurately. Accurate organoid instance segmentation is critical for…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Gui Huang , Kangyuan Zheng , Xuan Cai , Jiaqi Wang , Jianjia Zhang , Kaida Ning , Wenbo Wei , Yujuan Zhu , Jiong Zhang , Mengting Liu

Hepatic echinococcosis (HE) is a widespread parasitic disease in underdeveloped pastoral areas with limited medical resources. While CNN-based and Transformer-based models have been widely applied to medical image segmentation, CNNs lack…

Image and Video Processing · Electrical Eng. & Systems 2025-06-26 Jiayan Chen , Kai Li , Yulu Zhao , Jianqiang Huang , Zhan Wang

Ovarian cancer is one of the most serious cancers that threaten women around the world. Epithelial ovarian cancer (EOC), as the most commonly seen subtype of ovarian cancer, has rather high mortality rate and poor prognosis among various…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Tianling Liu , Ran Su , Changming Sun , Xiuting Li , Leyi Wei

Endoscopy is a crucial tool for diagnosing the gastrointestinal tract, but its effectiveness is often limited by a narrow field of view and the dynamic nature of the internal environment, especially in the esophagus, where complex and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Muyang Li , Juming Xiong , Ruining Deng , Tianyuan Yao , Regina N Tyree , Girish Hiremath , Yuankai Huo

In computational pathology, automatic nuclei instance segmentation plays an essential role in whole slide image analysis. While many computerized approaches have been proposed for this task, supervised deep learning (DL) methods have shown…

Image and Video Processing · Electrical Eng. & Systems 2023-08-04 Amirreza Mahbod , Christine Polak , Katharina Feldmann , Rumsha Khan , Katharina Gelles , Georg Dorffner , Ramona Woitek , Sepideh Hatamikia , Isabella Ellinger

Oral epithelial dysplasia (OED) is a pre-malignant histopathological diagnosis given to lesions of the oral cavity. Predicting OED grade or whether a case will transition to malignancy is critical for early detection and appropriate…

Image and Video Processing · Electrical Eng. & Systems 2021-09-02 Adam J. Shephard , Simon Graham , R. M. Saad Bashir , Mostafa Jahanifar , Hanya Mahmood , Syed Ali Khurram , Nasir M. Rajpoot

We address the problem of automated nuclear segmentation, classification, and quantification from Haematoxylin and Eosin stained histology images, which is of great relevance for several downstream computational pathology applications. In…

Computer Vision and Pattern Recognition · Computer Science 2022-04-19 Lihao Liu , Chenyang Hong , Angelica I. Aviles-Rivero , Carola-Bibiane Schönlieb

Introduction: Electrical impedance spectroscopy (EIS) has recently developed as a novel diagnostic device for screening and evaluating cervical dysplasia, prostate cancer, breast cancer and basal cell carcinoma. The current study aimed to…

Quantitative Methods · Quantitative Biology 2024-08-23 Vaibhav Gupta , Poonam Goel , Usha Agrawal , Neena Chaudhary , Garima Jain , Deepak Gupta

Wireless capsule endoscopy (WCE) is a non-invasive diagnostic procedure that enables visualization of the gastrointestinal (GI) tract. Deep learning-based methods have shown effectiveness in disease screening using WCE data, alleviating the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Qiaozhi Tan , Long Bai , Guankun Wang , Mobarakol Islam , Hongliang Ren

Video amodal segmentation is a particularly challenging task in computer vision, which requires to deduce the full shape of an object from the visible parts of it. Recently, some studies have achieved promising performance by using motion…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Ke Fan , Jingshi Lei , Xuelin Qian , Miaopeng Yu , Tianjun Xiao , Tong He , Zheng Zhang , Yanwei Fu

Osteoclast cell image analysis plays a key role in osteoporosis research, but it typically involves extensive manual image processing and hand annotations by a trained expert. In the last few years, a handful of machine learning approaches…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Sai Kumar Reddy Manne , Brendan Martin , Tyler Roy , Ryan Neilson , Rebecca Peters , Meghana Chillara , Christine W. Lary , Katherine J. Motyl , Michael Wan