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Eosinophilic esophagitis (EoE) is a chronic, food antigen-driven, allergic inflammatory condition of the esophagus associated with elevated esophageal eosinophils. EoE is a top cause of chronic dysphagia after GERD. Diagnosis of EoE relies…

The extraction of critical patient information from Electronic Health Records (EHRs) poses significant challenges due to the complexity and unstructured nature of the data. Traditional machine learning approaches often fail to capture…

Computation and Language · Computer Science 2025-09-03 Zhimeng Luo , Abhibha Gupta , Adam Frisch , Daqing He

Esophageal adenocarcinoma arises from Barrett's esophagus, which is the most serious complication of gastroesophageal reflux disease. Strategies for screening involve periodic surveillance and tissue biopsies. A major challenge in such…

Computer Vision and Pattern Recognition · Computer Science 2016-10-14 Anant S. Vemuri , Stephane A. Nicolau , Jacques Marescaux , Luc Soler , Nicholas Ayache

Pre-training large-scale neural language models on raw texts has made a significant contribution to improving transfer learning in natural language processing (NLP). With the introduction of transformer-based language models, such as…

Computation and Language · Computer Science 2024-05-08 Shoya Wada , Toshihiro Takeda , Shiro Manabe , Shozo Konishi , Jun Kamohara , Yasushi Matsumura

The aim of this paper is to evaluate whether large language models trained on multi-choice question data can be used to discriminate between medical subjects. This is an important and challenging task for automatic question answering. To…

Computation and Language · Computer Science 2024-03-22 Víctor Ponce-López

Fine-tuning pre-trained models have achieved impressive performance on standard natural language processing benchmarks. However, the resultant model generalizability remains poorly understood. We do not know, for example, how excellent…

Computation and Language · Computer Science 2023-01-26 Luoqiu Li , Xiang Chen , Hongbin Ye , Zhen Bi , Shumin Deng , Ningyu Zhang , Huajun Chen

The Bidirectional Encoder Representations from Transformers (BERT) model has achieved the state-of-the-art performance for many natural language processing (NLP) tasks. Yet, limited research has been contributed to studying its…

Computation and Language · Computer Science 2021-09-23 Zimin Wan , Chenchen Xu , Hanna Suominen

Early detection of esophagitis is important because this condition can progress to cancer if left untreated. However, the accuracies of different deep learning models in detecting esophagitis have yet to be compared. Thus, this study aimed…

Image and Video Processing · Electrical Eng. & Systems 2023-01-09 Kyoka Yoshiok , Kensuke Tanioka , Satoru Hiwa , Tomoyuki Hiroyasu

With the tremendous increase in the amount of biological literature, developing automated methods for extracting big data from papers, building models and explaining big mechanisms becomes a necessity. We describe here our approach to…

Molecular Networks · Quantitative Biology 2017-06-14 Khaled Sayed , Cheryl A. Telmer , Adam A. Butchy , Natasa Miskov-Zivanov

This paper presents an improved LLM based model for Grammatical Error Detection (GED), which is a very challenging and equally important problem for many applications. The traditional approach to GED involved hand-designed features, but…

Computation and Language · Computer Science 2024-11-26 Rahul Nihalani , Kushal Shah

Colonoscopy is used for colorectal cancer (CRC) screening. Extracting details of the colonoscopy findings from free text in electronic health records (EHRs) can be used to determine patient risk for CRC and colorectal screening strategies.…

Computation and Language · Computer Science 2021-08-26 Shashank Reddy Vadyala , Eric A. Sherer

Eosinophilic Esophagitis (EoE) is an inflammatory esophageal disease which is increasing in prevalence. The diagnostic gold-standard involves manual review of a patient's biopsy tissue sample by a clinical pathologist for the presence of 15…

Image and Video Processing · Electrical Eng. & Systems 2021-01-15 William Adorno , Alexis Catalano , Lubaina Ehsan , Hans Vitzhum von Eckstaedt , Barrett Barnes , Emily McGowan , Sana Syed , Donald E. Brown

In healthcare, it is essential to explain the decision-making process of machine learning models to establish the trustworthiness of clinicians. This paper introduces BI-RADS-Net, a novel explainable deep learning approach for cancer…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Boyu Zhang , Aleksandar Vakanski , Min Xian

Epilepsy is one of the most common neurological disorders that can be diagnosed through electroencephalogram (EEG), in which the following epileptic events can be observed: pre-ictal, ictal, post-ictal, and interictal. In this paper, we…

Machine Learning · Computer Science 2021-02-12 Jefferson Tales Oliva , João Luís Garcia Rosa

Biomedical literature is a rapidly expanding field of science and technology. Classification of biomedical texts is an essential part of biomedicine research, especially in the field of biology. This work proposes the fine-tuned DistilBERT,…

Computation and Language · Computer Science 2024-04-23 Ziqing Guo

Gastrointestinal (GI) tract cancers account for a substantial portion of the global cancer burden, where early diagnosis is critical for improved management and patient outcomes. The complex aetiologies and overlapping symptoms across GI…

Computation and Language · Computer Science 2025-03-19 Aniket Deroy , Subhankar Maity

We evaluated the viability of using a Large Language Model (LLM) to extract patient-specific specific toxicity and progression outcomes from unstructured radiology reports. We retrospectively extracted 160 follow-up CT and PET/CT electronic…

Medical Physics · Physics 2026-03-02 Justin Pijanowski , Yakout Mezgueldi , Alan Lee , Drew Moghanaki , Ricky R. Savjani , James Lamb

The integration of Large Language Models (LLMs) into biomedical research offers new opportunities for domainspecific reasoning and knowledge representation. However, their performance depends heavily on the semantic quality of training…

Background: Manual extraction of pancreatic cystic lesion (PCL) features from radiology reports is labor-intensive, limiting large-scale studies needed to advance PCL research. Purpose: To develop and evaluate large language models (LLMs)…

In this research, we explored the improvement in terms of multi-class disease classification via pre-trained language models over Medical-Abstracts-TC-Corpus that spans five medical conditions. We excluded non-cancer conditions and examined…

Computation and Language · Computer Science 2024-11-20 Ahmed Akib Jawad Karim , Muhammad Zawad Mahmud , Samiha Islam , Aznur Azam