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A theoretical model for stratified epithelium is presented. The viscoelastic properties of the tissue is assumed to be dependent on the spatial distribution of proliferative and differentiated cells. Based on this assumption, a hydrodynamic…

Biological Physics · Physics 2016-06-08 Wei-Ting Yeh , Hsuan-Yi Chen

Active nematics are an important new paradigm in soft condensed matter systems. They consist of rod-like components with an internal driving force pushing them out of equilibrium. The resulting fluid motion exhibits chaotic advection, in…

Being intrinsically nonequilibrium, active materials can potentially perform functions that would be thermodynamically forbidden in passive materials. However, active systems have diverse local attractors that correspond to distinct…

Soft Condensed Matter · Physics 2024-10-16 Saptorshi Ghosh , Aparna Baskaran , Michael F. Hagan

A constitutive relation between stress and strain relative to a reference state is the basic assumption of elasticity theory. However, in living matter, force generation is governed by motor molecule activity, which does not depend on…

Soft Condensed Matter · Physics 2026-03-17 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

A body immersed in a nematic liquid crystal disturbs the fluid's preferred molecular configuration and increases its stored elastic energy. In an active nematic, the fluid components also generate a stress in the bulk fluid. By introducing…

Soft Condensed Matter · Physics 2025-06-17 Thomas G. J. Chandler , Saverio E. Spagnolie

We study a continuum model of an extensile active nematic to show that mesoscale turbulence develops in two stages: (i) ordered regions undergo an intrinsic hydrodynamic instability generating walls, lines of stong bend deformations, (ii)…

Soft Condensed Matter · Physics 2015-06-18 Sumesh P. Thampi , Ramin Golestanian , Julia M. Yeomans

We use continuum simulations to study the impact of anisotropic hydrodynamic friction on the emergent flows of active nematics. We show that, depending on whether the active particles align with or tumble in their collectively self-induced…

Soft Condensed Matter · Physics 2020-03-16 Kristian Thijssen , Luuk Metselaar , Julia M. Yeomans , Amin Doostmohammadi

Plant morphogenesis relies on dynamic growth deformations at the cell and tissue scales driven by osmotic fluxes. A mechanistic understanding of this phenomenon demands a physical framework that integrates cell imbibition, tissue mechanics,…

Biological Physics · Physics 2025-12-08 Hadrien Oliveri , Christophe Godin , Ibrahim Cheddadi

Hydrodynamic theories effectively describe many-body systems out of equilibrium in terms of a few macroscopic parameters. However, such hydrodynamic parameters are difficult to derive from microscopics. Seldom is this challenge more…

Continuum models of active nematic gels have proved successful to describe a number of biological systems consisting of a population of rodlike motile subunits in a fluid environment. However, in order to get a thorough understanding of the…

Soft Condensed Matter · Physics 2023-05-03 Stefano Turzi

The interplay between active matter and its environment is central to understanding emergent behavior in biological and synthetic systems. Here, we show that coupling active nematic flows to small-amplitude deformations of a compliant…

Soft Condensed Matter · Physics 2026-01-19 Varun Venkatesh , Amin Doostmohammadi

We investigate the dynamics of active nematic liquid crystals on deformable membranes, focusing on the interplay between active stress and anisotropic curvature coupling. Using a minimal model, we simulate the coupled evolution of the…

Soft Condensed Matter · Physics 2026-05-19 Yuki Hirota , Nariya Uchida

One of the defining features of active nematics is that above a critical activity the quiescent state becomes unstable to a distorted, flowing one. We show that spatial variations in activity can fundamentally change the nature of this…

Soft Condensed Matter · Physics 2025-12-15 Alexander J. H. Houston , Michael Grinfeld , Geoff McKay , Nigel J. Mottram

We numerically study the effect of an active turbulent environment on a passive deformable droplet. The system is simulated using coupled hydrodynamic and nematodynamic equations for nematic liquid crystals with an active stress which is…

Soft Condensed Matter · Physics 2024-05-06 Chamkor Singh , Abhishek Chaudhuri

We propose an agent-based model of active flexible rods. Inspired by cytoskeletal flows, we introduce activity by an internal flow that contributes to the dissipative forces. The active force between our agents is central and reciprocal,…

Soft Condensed Matter · Physics 2026-03-06 Mathieu Dedenon , Carles Blanch-Mercader , Karsten Kruse , Jens Elgeti

Recent studies have shown that packings of cells, both eukaryotic cellular tissues and growing or swarming bacterial colonies, can often be understood as active nematic fluids. A key property of volume-conserving active nematic model…

Soft Condensed Matter · Physics 2022-05-12 Fabian Jan Schwarzendahl , Daniel A. Beller

During the early-stages of embryo development, morphogenesis--- the emergence of shape and form in living organisms--- is almost exclusively associated with monolayers of tightly bound epithelial cells. To understand how such tissues change…

Soft Condensed Matter · Physics 2019-08-28 Richard G. Morris , Madan Rao

We analyze the phase behavior of lyotropic nematic liquid crystals in the self-organizing flow, viz. so called active nematics (AN). Their elastic properties are mutually caused by evolution of topological defects (for instance,…

Soft Condensed Matter · Physics 2018-02-20 L. V. Elnikova

We use active nematohydrodynamics to study the flow of an active fluid in a 3D microchannel, finding a transition between active turbulence and regimes where there is a net flow along the channel. We show that the net flow is only possible…

Soft Condensed Matter · Physics 2020-10-07 Santhan Chandragiri , Amin Doostmohammadi , Julia M. Yeomans , Sumesh P. Thampi

The structure of a molecular liquid, in both the nematic liquid crystalline and isotropic phases, around a cylindrical macroparticle, is studied using density functional theory. In the nematic phase the structure of the fluid is highly…

Soft Condensed Matter · Physics 2009-11-11 David L. Cheung , Michael P. Allen