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Automatically labeling intracranial arteries (ICA) with their anatomical names is beneficial for feature extraction and detailed analysis of intracranial vascular structures. There are significant variations in the ICA due to natural and…

Computer Vision and Pattern Recognition · Computer Science 2020-07-30 Li Chen , Thomas Hatsukami , Jenq-Neng Hwang , Chun Yuan

Deviation of blood flow from an optimal range is known to be associated with the initiation and progression of vascular pathologies. Important open questions remain about how the abnormal flow drives specific wall changes in pathologies…

Coronary artery disease (CAD) is one of the most common cardiac diseases worldwide and causes disability and economic burden. It is the world's leading and most serious cause of mortality, with approximately 80% of deaths reported in low-…

Machine Learning · Computer Science 2022-10-28 Anas Maach , Jamila Elalami , Noureddine Elalami , El Houssine El Mazoudi

While ischemic stroke is a leading cause of death worldwide, there has been little success translating putative cerebroprotectants from rodent preclinical trials to human patients. We investigated computational image-based assessment tools…

Atherosclerotic lesions within carotid and cerebral vessels are likely to influence hemodynamics and manifest into vascular pathologies, including Alzheimers Disease and ischemic stroke. Hemodynamics are influenced by changes in luminal…

Tissues and Organs · Quantitative Biology 2023-03-24 Jennifer Buoncore , Alexis Sobecki , Brian Lee Beatty

An important step for any causal inference study design is understanding the distribution of the treated and control subjects in terms of measured baseline covariates. However, not all baseline variation is equally important. In the…

Methodology · Statistics 2021-07-02 Rachael C. Aikens , Michael Baiocchi

Purpose: The motion of the common carotid artery tissue layers along the vessel axis during the cardiac cycle, observed in ultrasound imaging, is associated with the presence of established cardiovascular risk factors. However, the vast…

Medical Physics · Physics 2020-07-27 Guillaume Zahnd , Kozue Saito , Kazuyuki Nagatsuka , Yoshito Otake , Yoshinobu Sato

Coronary artery calcium (CAC) is highly predictive of cardiovascular events. While millions of chest CT scans are performed annually in the United States, CAC is not routinely quantified from scans done for non-cardiac purposes. A deep…

The goal is to develop a novel approach for cardiac disease prediction and diagnosis using intelligent agents. Initially the symptoms are preprocessed using filter and wrapper based agents. The filter removes the missing or irrelevant…

Multiagent Systems · Computer Science 2010-09-28 Murugesan Kuttikrishnan

The classification of carotid artery ultrasound images is a crucial means for diagnosing carotid plaques, holding significant clinical relevance for predicting the risk of stroke. Recent research suggests that utilizing plaque segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-01-30 Haitao Gan , Lingchao Fu , Ran Zhou , Weiyan Gan , Furong Wang , Xiaoyan Wu , Zhi Yang , Zhongwei Huang

Coronary heart disease (CHD) remains a leading cause of mortality worldwide. This study introduces a novel approach that integrates patient-specific Multi-slice CT scans into CAD models, using a one-dimensional numerical framework to assess…

Medical Physics · Physics 2025-05-21 Priyanshu Ghosh , Sayan Karmakar , Disha Mondal , Oeshee Roy , Supratim Saha

Coronary Artery Disease (CAD) remains a leading cause of morbidity and mortality worldwide. Early detection is critical to recover patient outcomes and decrease healthcare costs. In recent years, machine learning (ML) advancements have…

Artificial Intelligence · Computer Science 2026-03-10 Karan Kumar Singh , Nikita Gajbhiye , Gouri Sankar Mishra

Coronary heart disease (CHD) is the leading cause of adult death in the United States and worldwide, and for which the coronary angiography procedure is the primary gateway for diagnosis and clinical management decisions. The…

Computer-aided diagnosis (CAD) systems stand out as potent aids for physicians in identifying the novel Coronavirus Disease 2019 (COVID-19) through medical imaging modalities. In this paper, we showcase the integration and reliable and fast…

Image and Video Processing · Electrical Eng. & Systems 2024-03-13 Demetris Gerogiannis , Anastasios Arsenos , Dimitrios Kollias , Dimitris Nikitopoulos , Stefanos Kollias

Advances in optical coherence tomography (OCT) have enabled noninvasive imaging of substructures of the human retina with high spatial resolution. OCT examinations are now a standard procedure in clinics and an integral part of ophthalmic…

Human-Computer Interaction · Computer Science 2022-12-22 Martin Röhlig , Oliver Stachs , Heidrun Schumann

This paper describes an ongoing multi-scale visual analytics approach for exploring and analyzing biomedical knowledge at scale.We utilize global and local views, hierarchical and flow-based graph layouts, multi-faceted search, neighborhood…

Human-Computer Interaction · Computer Science 2021-10-22 Fahd Husain , Rosa Romero-Gomez , Emily Kuang , Dario Segura , Adamo Carolli , Lai Chung Liu , Manfred Cheung , Yohann Paris

Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…

Coronary artery calcification (CAC) is a strong and independent predictor of cardiovascular disease (CVD). However, manual assessment of CAC often requires radiological expertise, time, and invasive imaging techniques. The purpose of this…

Computer Vision and Pattern Recognition · Computer Science 2024-02-16 Andrew M. Nguyen , Jianfei Liu , Tejas Sudharshan Mathai , Peter C. Grayson , Ronald M. Summers

Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Pan Du , Delin An , Chaoli Wang , Jian-Xun Wang

Coronary Microvascular Dysfunction (CMD) is characterized by impaired vasodilation and can lead to insufficient blood flow to the myocardium during stress or exertion, affecting millions of people globally. Despite their diagnostic value,…

Computational Engineering, Finance, and Science · Computer Science 2025-08-04 Haizhou Yang , Jiyang Zhang , Ismael Z. Assi , Brahmajee K. Nallamothu , Krishna Garikipati , C. Alberto Figueroa
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