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Precise manipulation of fluids and objects on the micro scale is seldom a simple task, but nevertheless crucial for many applications in life sciences and chemical engineering. We present a microfluidic chip fabricated in silicon-glass,…

Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Pan Du , Delin An , Chaoli Wang , Jian-Xun Wang

Acoustic tweezers are gaining increasing attention due to their excellent biological compatibility. Recently, the concept of topology has been expanded from condensed matter physics into acoustics, giving rise to a robust wave manipulation…

Applied Physics · Physics 2021-06-23 Hongqing Dai , Linbo Liu , Baizhan Xia , Dejie Yu

Acoustic traps are used to capture and handle suspended microparticles and cells in microfluidic applications. A particular simple and much-used acoustic trap consists of a commercially available, millimeter-sized, liquid-filled glass…

Fluid Dynamics · Physics 2017-08-30 Mikkel W. H. Ley , Henrik Bruus

The acoustofluidic method holds great promise for manipulating microorganisms. When exposed to the steady vortex structures of acoustic streaming flow, these microorganisms exhibit intriguing dynamic behaviors, such as hydrodynamic trapping…

Fluid Dynamics · Physics 2025-04-25 Xuyang Sun , Wenchang Tan , Yi Man

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…

Acoustic tweezers comprising a surface acoustic wave chip and a disposable silicon microfluidic chip are potentially advantageous to stable and cost-ffective acoustofluidic experiments while avoiding the cross-contamination by reusing the…

Fluid Dynamics · Physics 2024-11-11 Shichao Jia , Soichiro Tsujino

We study by numerical simulation in two and three dimensions the coupling layer between the transducer and the microfluidic chip in ultrasound acoustofluidic devices. The model includes the transducer with electrodes, the microfluidic chip…

Fluid Dynamics · Physics 2021-07-30 William Naundrup Bodé , Henrik Bruus

We describe a numerical method to simulate an elastic shell immersed in a viscous incompressible fluid. The method is developed as an extension of the immersed boundary method using shell equations based on the Kirchhoff-Love and the planar…

Numerical Analysis · Mathematics 2025-10-20 E. Givelberg

The flow profile in a capillary gap and the pumping efficiency of an acoustic micropump employing Surface Acoustic Waves is investigated both experimentally and theoretically. Such ultrasonic surface waves on a piezoelectric substrate…

Soft Condensed Matter · Physics 2007-05-23 Z. Guttenberg , A. Rathgeber , S. Keller , J. O. Rädler , A. Wixforth , M. Kostur , M. Schindler , P. Talkner

The ability to precisely trap, transport and manipulate micrometer-sized objects, including biological cells, DNA-coated microspheres and microorganisms, is very important in life science studies and biomedical applications. In this study,…

Fluid Dynamics · Physics 2012-07-05 Gan Yu , Xiaolin Chen , Jie Xu

Vessels are complex structures in the body that have been studied extensively in multiple representations. While voxelization is the most common of them, meshes and parametric models are critical in various applications due to their…

This paper presents a microfluidic device that implements standing surface acoustic waves in order to handle single cells, droplets, and generally particles. The particles are moved in a very controlled manner by the two-dimensional…

Fluid Dynamics · Physics 2012-11-14 S. B. Q. Tran , Philippe Marmottant , Pierre Thibault

We systematically engineer a series of square and rectangular phononic crystals to create experimental realisations of complex topological phononic circuits. The exotic topological transport observed is wholly reliant upon the underlying…

Integrated acoustic circuits leverage guided acoustic waves for applications ranging from radio-frequency filters to quantum state transfer, biochemical sensing and nanomechanical computing. In many applications it is desirable to have a…

Mathematical models and numerical simulations are widely used in the field of hemodynamics, representing a valuable resource to better understand physiological and pathological processes. The theory behind the phenomenon is closely related…

Fluid Dynamics · Physics 2021-06-15 Giulia Bertaglia , Valerio Caleffi , Alessandro Valiani

Phononic circuits constructed from high tensile stress membranes offer a range of desirable features such as high acoustic confinement, controllable nonlinearities, low mass, compact footprint, and ease of fabrication. This tutorial…

Straight cylindrical stethoscopes serve as an important alternative to conventional stethoscopes whose application in the treatment of infectious diseases might be limited by the use of protective clothing. Yet their miniaturization is…

Applied Physics · Physics 2023-06-05 Zheng-Ji Chen , Jing-Jing Liu , Bin Liang , Jing Yang , Jian-Chun Cheng

We present an effective thermoviscous theory of acoustofluidics including pressure acoustics, thermoviscous boundary layers, and streaming for fluids embedded in elastic cavities. By including thermal fields, we thus extend the effective…

Fluid Dynamics · Physics 2021-07-30 Jonas H. Joergensen , Henrik Bruus

In vivo measurement of the mechanical properties of thin-walled soft tissues (e.g., mitral valve, artery and bladder) and in situ mechanical characterization of thin-walled artificial soft biomaterials in service are of great challenge and…

Soft Condensed Matter · Physics 2020-09-02 Guo-Yang Li , Qiong He , Robert Mangan , Guoqiang Xu , Chi Mo , Jianwen Luo , Michel Destrade , Yanping Cao
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