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Background Analyzing images to accurately estimate the number of different cell types in the brain using automatic methods is a major objective in neuroscience. The automatic and selective detection and segmentation of neurons would be an…

Image and Video Processing · Electrical Eng. & Systems 2024-10-07 Antonio LaTorre , Lidia Alonso-Nanclares , José María Peña , Javier De Felipe

Accurately segmenting different organs from medical images is a critical prerequisite for computer-assisted diagnosis and intervention planning. This study proposes a deep learning-based approach for segmenting various organs from CT and…

Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…

Quantitative Methods · Quantitative Biology 2025-08-26 Surajit Das , Gourav Roy , Pavel Zun

Deep convolutional neural networks have achieved remarkable progress on a variety of medical image computing tasks. A common problem when applying supervised deep learning methods to medical images is the lack of labeled data, which is very…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Xiaomeng Li , Lequan Yu , Hao Chen , Chi-Wing Fu , Lei Xing , Pheng-Ann Heng

Microscopy images contain rich information about how cells respond to perturbations, making them essential to applications like drug screening. To quantify images, researchers often use representation extraction methods, and recent years…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Emre Hayir , Lorin Crawford , Alex X. Lu

Recent innovations in light sheet microscopy, paired with developments in tissue clearing techniques, enable the 3D imaging of large mammalian tissues with cellular resolution. Combined with the progress in large-scale data analysis, driven…

Medical image segmentation is vital to the area of medical imaging because it enables professionals to more accurately examine and understand the information offered by different imaging modalities. The technique of splitting a medical…

Image and Video Processing · Electrical Eng. & Systems 2024-09-01 Aitik Gupta , Joydip Dhar

We propose TG-LMM (Text-Guided Large Multi-Modal Model), a novel approach that leverages textual descriptions of organs to enhance segmentation accuracy in medical images. Existing medical image segmentation methods face several challenges:…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Yihao Zhao , Enhao Zhong , Cuiyun Yuan , Yang Li , Man Zhao , Chunxia Li , Jun Hu , Chenbin Liu

Image segmentation plays an essential role in medicine for both diagnostic and interventional tasks. Segmentation approaches are either manual, semi-automated or fully-automated. Manual segmentation offers full control over the quality of…

Computer Vision and Pattern Recognition · Computer Science 2019-03-21 Tomas Sakinis , Fausto Milletari , Holger Roth , Panagiotis Korfiatis , Petro Kostandy , Kenneth Philbrick , Zeynettin Akkus , Ziyue Xu , Daguang Xu , Bradley J. Erickson

A key component towards an improved and fast cancer diagnosis is the development of computer-assisted tools. In this article, we present the solution that won the SegPC-2021 competition for the segmentation of multiple myeloma plasma cells…

Image and Video Processing · Electrical Eng. & Systems 2021-11-10 Álvaro García Faura , Dejan Štepec , Tomaž Martinčič , Danijel Skočaj

The present paper develops a general methodology for the morphological segmentation of hyperspectral images, i.e., with an important number of channels. This approach, based on watershed, is composed of a spectral classification to obtain…

Image and Video Processing · Electrical Eng. & Systems 2020-10-05 Guillaume Noyel , Jesus Angulo , Dominique Jeulin

Many computer vision systems require low-cost segmentation algorithms based on deep learning, either because of the enormous size of input images or limited computational budget. Common solutions uniformly downsample the input images to…

Computer Vision and Pattern Recognition · Computer Science 2022-08-19 Chen Jin , Ryutaro Tanno , Thomy Mertzanidou , Eleftheria Panagiotaki , Daniel C. Alexander

Cell image classification methods are currently being used in numerous applications in cell biology and medicine. Applications include understanding the effects of genes and drugs in screening experiments, understanding the role and…

Quantitative Methods · Quantitative Biology 2022-03-04 Mohammad Shifat-E-Rabbi , Xuwang Yin , Cailey Elizabeth Fitzgerald , Gustavo K. Rohde

The semantic image segmentation task consists of classifying each pixel of an image into an instance, where each instance corresponds to a class. This task is a part of the concept of scene understanding or better explaining the global…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Saeid Asgari Taghanaki , Kumar Abhishek , Joseph Paul Cohen , Julien Cohen-Adad , Ghassan Hamarneh

Cell and nucleus segmentation are fundamental tasks for quantitative bioimage analysis. Despite progress in recent years, biologists and other domain experts still require novel algorithms to handle increasingly large and complex real-world…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Thibaut Goldsborough , Ben Philps , Alan O'Callaghan , Fiona Inglis , Leo Leplat , Andrew Filby , Hakan Bilen , Peter Bankhead

High-throughput screening using automated microscopes is a key driver in biopharma drug discovery, enabling the parallel evaluation of thousands of drug candidates for diseases such as cancer. Traditional image analysis and deep learning…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Jacob Hanimann , Daniel Siegismund , Mario Wieser , Stephan Steigele

Segmentation is a fundamental process in microscopic cell image analysis. With the advent of recent advances in deep learning, more accurate and high-throughput cell segmentation has become feasible. However, most existing deep…

Computer Vision and Pattern Recognition · Computer Science 2020-06-25 Hyeonsoo Lee , Won-Ki Jeong

Reliable cell segmentation and classification from biomedical images is a crucial step for both scientific research and clinical practice. A major challenge for more robust segmentation and classification methods is the large variations in…

Cell Behavior · Quantitative Biology 2017-10-31 Mo Zhang , Xiang Li , Mengjia Xu , Quanzheng Li

Live cell microscopy sequences exhibit complex spatial structures and complicated temporal behaviour, making their analysis a challenging task. Considering cell segmentation problem, which plays a significant role in the analysis, the…

Computer Vision and Pattern Recognition · Computer Science 2019-01-08 Assaf Arbelle , Tammy Riklin Raviv

Image segmentation is a central topic in image processing and computer vision and a key issue in many applications, e.g., in medical imaging, microscopy, document analysis and remote sensing. According to the human perception, image…

Numerical Analysis · Mathematics 2022-06-24 Laura Antonelli , Valentina De Simone , Daniela di Serafino
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