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We present an ultra-thin hybrid imaging system based on an optical multimode fiber (MMF) and an optical fiber hydrophone that combines optical resolution photoacoustic and fluorescence microscopy. To control the illumination at the distal…

In situ polymerization and micropatterning of hydrogels on-chip opens the potential for many applications such as tracking and controlling the diffusion of molecules, stimulants, inhibitors, as well as nutrients and drugs, from their source…

Surface plasmon resonance (SPR) sensors built on photonic crystal fibers (PCFs) have recently become a promising category of optical sensing platforms. This is primarily due to their high sensitivity, compact structural design and ability…

Stochastic modeling has become a popular approach to quantify uncertainty in flows through heterogeneous porous media. The uncertainty in heterogeneous structure properties is often parameterized by a high-dimensional random variable. This…

Numerical Analysis · Mathematics 2013-10-22 Lijian Jiang , J. David Moulton , Jia Wei

Concatenated modal interferometers based multipoint sensing system for detection of instantaneous amplitude, frequency, and phase of mechanical vibrations is proposed and demonstrated. The sensor probes are fabricated using identical…

Instrumentation and Detectors · Physics 2021-05-17 Kalipada Chatterjee , Venugopal Arumuru , Dhananjay Patil , Rajan Jha

Advances in flexible catheters pave the way for minimally invasive diagnosis and treatment of luminal organs and tubular structures through endoluminal interventions. A key challenge is in establishing non-constraining pressure monitoring…

Medical Physics · Physics 2025-11-04 Xiaotong Guo , Qindong Zheng , Jinshi Zhao , Bing Li , Eric Morgan Yeatman

Label-free detecting multiple analytes in a high-throughput fashion has been one of the long-sought goals in biosensing applications. Yet, for all-optical approaches, interfacing state-of-the-art label-free techniques with microfluidics…

Quantitative Methods · Quantitative Biology 2023-08-14 Alexia Stollmann , Jose Garcia-Guirado , Jae-Sang Hong , Hyungsoon Im , Hakho Lee , Jaime Ortega Arroyo , Romain Quidant

We have demonstrated the fabrication and characterization of 2D liquid-based multimode optical waveguide structures over a Polydimethylsiloxane (PDMS) material-based chip. Fabrication of two separate microstructures, one with a width of 14…

Optics · Physics 2023-01-27 Sanyogita , Amar Ghar , P. K. Panigrahi

It is widely agreed that phase change materials (PCMs) are of high interest for sustainable energy future. Many of the applications require anti-leakage properties of PCM, that can be accomplished through PCM encapsulation. In this study,…

Displacement measuring interferometry is a crucial component in metrology applications. In this paper, we propose a fiber-based two-wavelength heterodyne interferometer as a compact and highly sensitive displacement sensor that can be used…

Optics · Physics 2022-09-09 Yanqi Zhang , Felipe Guzman

Point cloud capture processes are error-prone and introduce noisy artifacts that necessitate filtering/denoising. Recent filtering methods often suffer from point clustering or noise retaining issues. In this paper, we propose Hybrid Point…

Graphics · Computer Science 2025-08-13 Dasith de Silva Edirimuni , Xuequan Lu , Ajmal Saeed Mian , Lei Wei , Gang Li , Scott Schaefer , Ying He

We demonstrate a quantitative broadband fiber sensor, based on evanescent field sensing in the cladding holes of an air-suspended solid-core photonic crystal fiber. We discuss the fabrication process, together with the structural- and…

We present a multiparticle collision dynamics (MPC) implementation of layered immiscible fluids $A$ and $B$ of different shear viscosities separated by planar interfaces. The simulated flow profile for imposed steady shear motion and the…

Soft Condensed Matter · Physics 2021-09-07 Zihan Tan , Vania Calandrini , Jan K. G. Dhont , Gerhard Nägele , Roland G. Winkler

This paper describes a micro fluorescence in situ hybridization ({\mu}FISH)-based rapid detection of cytogenetic biomarkers on formalin-fixed paraffin embedded (FFPE) tissue sections. We demonstrated this method in the context of detecting…

Tissues and Organs · Quantitative Biology 2018-06-19 Deborah Huber , Govind V. Kaigala

Microwave sensors can probe intrinsic material properties of analytes in a microfluidic channel at physiologically relevant ion concentrations. While microwave sensors have been used to detect single cells and microparticles in earlier…

Advances in silicon photonics have resulted in rapidly increasing complexity of integrated circuits. New methods are desirable that allow direct characterization of individual optical components in-situ, without the need for additional…

In situ measurement of analytes for in vivo or in vitro systems has been challenging due to the bulky size of traditional analytical instruments. Also, frequent in vitro concentration measurements rely on fluorescence-based methods or…

Optically levitated micro- and nanoparticles offer an ideal playground for investigating photon-phonon interactions over macroscopic distances. Here we report the observation of long-range optical binding of multiple microparticles,…

Rapid and accessible cardiac biomarker testing is essential for the timely diagnosis and risk assessment of myocardial infarction (MI) and heart failure (HF), two interrelated conditions that frequently coexist and drive recurrent…

We demonstrate the design, fabrication and use of a dual electrode PMUT (Piezoelectric Micromachined Ultrasound Transducer) integrated with a microfluidic channel as a fluid density sensor in both static and dynamic density-change…