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Fourier ptychographic microscopy (FPM) is a recently developed imaging modality that uses angularly varying illumination to extend a system performance beyond the limit defined by its optical elements. The FPM technique applies a novel…

Optics · Physics 2014-05-02 Xiaoze Ou , Roarke Horstmeyer , Changhuei Yang , Guoan Zheng

Nonlinear computation is essential for a wide range of information processing tasks, yet implementing nonlinear functions using optical systems remains a challenge due to the weak and power-intensive nature of optical nonlinearities.…

Optics · Physics 2025-11-10 Md Sadman Sakib Rahman , Yuhang Li , Xilin Yang , Shiqi Chen , Aydogan Ozcan

Complex-field imaging is indispensable for numerous applications at wavelengths from X-ray to THz, with amplitude describing transmittance (or reflectivity) and phase revealing intrinsic structure of the target object. Coherent diffraction…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Meng Li , Liheng Bian , Guoan Zheng , Andrew Maiden , Yang Liu , Yiming Li , Qionghai Dai , Jun Zhang

Due to its specificity, fluorescence microscopy (FM) has become a quintessential imaging tool in cell biology. However, photobleaching, phototoxicity, and related artifacts continue to limit FM's utility. Recently, it has been shown that…

Quantitative phase microscopy (QPM) is a label-free technique that enables to monitor morphological changes at subcellular level. The performance of the QPM system in terms of spatial sensitivity and resolution depends on the coherence…

Despite offering high sensitivity, a high signal-to-noise ratio, and a broad spectral range, single-pixel imaging (SPI) is limited by low measurement efficiency and long data-acquisition times. To address this, we propose a…

Quantitative phase microscopy (QPM) has found significant applications in the field of biomedical imaging which works on the principle of interferometry. The theory behind achieving interference in QPM with conventional light sources such…

Optics · Physics 2021-07-26 Azeem Ahmad , Nikhil Jayakumar , Balpreet Singh Ahluwalia

Optical microscopy has been employed to derive salient characteristics of an object in various fields, including cell biology, flow cytometry, biopsy, and neuroscience. In particular, measuring the phase of light scattered from an object…

Optics · Physics 2025-03-18 Jeonghun Oh , Herve Hugonnet , Weisun Park , YongKeun Park

Quasiparticle interference (QPI) imaging is a powerful tool for probing electronic structures in quantum materials, but extracting the single-scatterer QPI pattern (i.e., the kernel) from a multi-scatterer image remains a fundamentally…

Machine Learning · Computer Science 2026-02-16 Yingshuai Ji , Haomin Zhuang , Matthew Toole , James McKenzie , Xiaolong Liu , Xiangliang Zhang

Spectral imaging is a fundamental diagnostic technique with widespread application. Conventional spectral imaging approaches have intrinsic limitations on spatial and spectral resolutions due to the physical components they rely on. To…

Image and Video Processing · Electrical Eng. & Systems 2021-06-07 Figen S. Oktem , Oğuzhan Fatih Kar , Can Deniz Bezek , Farzad Kamalabadi

Experimental quantum simulators have become large and complex enough that discovering new physics from the huge amount of measurement data can be quite challenging, especially when little theoretical understanding of the simulated model is…

Quantum Physics · Physics 2020-12-08 Alexander Lidiak , Zhexuan Gong

Lensless fiber endomicroscope is an emerging tool for in-vivo microscopic imaging, where quantitative phase imaging (QPI) can be utilized as a label-free method to enhance image contrast. However, existing single-shot phase reconstruction…

Quantum techniques can be used to enhance the signal-to-noise ratio in optical imaging. Leveraging the latest advances in single photon avalanche diode array cameras and multi-photon detection techniques, here we introduce a super-sensitive…

Kernel phase interferometry (KPI) is a data processing technique that allows for the detection of asymmetries (such as companions or disks) in high-Strehl images, close to and within the classical diffraction limit. We show that KPI can…

Instrumentation and Methods for Astrophysics · Physics 2023-05-29 Alexander Chaushev , Steph Sallum , Julien Lozi , Frantz Martinache , Jeffrey Chilcote , Tyler Groff , Olivier Guyon , N. Jeremy Kasdin , Barnaby Norris , Andy Skemer

In optical detection of ultrasound, resonators with high Q-factors are often used to maximize sensitivity. However, in order to perform parallel interrogation, conventional interferometric techniques require an overlap between the resonator…

Optics · Physics 2019-01-27 Yoav Hazan , Amir Rosenthal

A single intensity-only holographic interferogram can records the full amplitude and phase information of optical field. However, current digital holography technologies cannot recover the lossless phase information from a single…

Image and Video Processing · Electrical Eng. & Systems 2020-03-09 Qinnan Zhang , Shengyu Lu , Jiaosheng Li , Wenjie Li , Dong Li , Xiaoxu Lu , Liyun Zhong , Jindong Tian

This article presents a thorough comparison of themain QPM techniques, focusing on their accuracy in terms of measurement precision and trueness. We focus on 8 techniques, namely digital holographic microscopy (DHM), cross-grating wavefront…

High-throughput 3D quantitative phase imaging (QPI) in flow cytometry enables label-free, volumetric characterization of individual cells by reconstructing their refractive index (RI) distributions from multiple viewing angles during flow…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Enze Ye , Wei Lin , Shaochi Ren , Yakun Liu , Xiaoping Li , Hao Wang , He Sun , Feng Pan

Coherent diffractive imaging is a technique that recovers the sample image by numerically inverting its diffraction pattern. We propose a generalization of this method for the inversion of multi-wavelength data. Using this approach, we show…

Optics · Physics 2020-05-08 Erik Malm , Edwin Fohtung , Anders Mikkelsen

We develop a quantum statistical framework for passive optical surface metrology. Modelling a surface as an incoherent ensemble of point emitters imaged through a diffraction-limited system, we employ techniques from quantum parameter…

Quantum Physics · Physics 2026-03-12 Jernej Frank , George Brumpton , Tommaso Tufarelli , Gerardo Adesso , Samanta Piano