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Intercellular signaling has an important role in organism development, but not all communication occurs using the same mechanism. Here, we analyze the energy efficiency of intercellular signaling by two canonical mechanisms: diffusion of…

Quantitative Methods · Quantitative Biology 2022-11-30 Hyunjoong Kim , Yoichiro Mori , Joshua B. Plotkin

Ultrafast electron microscopy (UEM) has found widespread applications in physics, chemistry, and materials science, enabling real-space imaging of dynamics on ultrafast timescales. Recent advances have pushed the temporal resolution of UEM…

Roughly half of a cells proteins are located at or near the plasma membrane. In this restricted space the cell senses its environment, signals to its neighbors and ex-changes cargo through exo- and endocytotic mechanisms. Ligands bind to…

Biological Physics · Physics 2019-10-02 Martin Oheim , Adi Salomon , Adam Weissman , Maia Brunstein , Ute Becherer

Optical microcavities and metallic nanostructures have been shown to significantly modulate the dynamics and spectroscopic response of molecular systems. We present a study of the nonlinear optics of a model consisting of $N$ anharmonic…

The lysyl oxidase (LOX) enzyme that catalyses cross-link formation during the assembly of collagen fibrils in vivo is too large to diffuse within assembled fibrils, and so is incompatible with a fully equilibrium mechanism for fibril…

Biological Physics · Physics 2021-09-30 Matthew P. Leighton , Laurent Kreplak , Andrew D. Rutenberg

The skin forms an efficient barrier against the environment, and rapid cutaneous wound healing after injury is therefore essential. Healing of the uppermost layer of the skin, the epidermis, involves collective migration of keratinocytes,…

Cell Behavior · Quantitative Biology 2015-07-31 Matthias Jörg Fuhr , Michael Meyer , Eric Fehr , Gilles Ponzio , Sabine Werner , Hans Jürgen Herrmann

A mechanism is explored whereby intense laser radiation induces an optical force between the constituent atoms of a molecule. In the case of a diatomic molecule the effect results in a modification of the vibrational potential, and using…

Optics · Physics 2007-05-23 D. L. Andrews R. G. Crisp

Formation of amyloid fibrils of various amyloidogenic proteins is dramatically enhanced by ultrasound irradiation. For applying this phenomenon to the study of protein aggregation science and diagnosis of neurodegenerative diseases, a…

Through mechanical forces, biological cells remodel the surrounding collagen network, generating striking deformation patterns. Tethers-tracts of high densification and fiber alignment-form between cells, thinner bands emanate from cell…

Line intensity mapping (LIM) experiments probing the nearby universe can expect a considerable amount of cosmic infrared background (CIB) contiuum emission coming from near and far-infrared galaxies. For the purpose of using the LIM data to…

Cosmology and Nongalactic Astrophysics · Physics 2023-07-26 Zilu Zhou , Abhishek S. Maniyar , Anthony R. Pullen

In solid tumors, cells constantly interact with the surrounding extracellular matrix. In particular cancer-associated fibroblasts modulate the architecture of the matrix by exerting forces and contracting collagen fibres, creating paths…

Quantitative Methods · Quantitative Biology 2022-07-22 Cedric Gommes , Thomas Louis , Isabelle Bourgot , Erik Maquoi , Silvia Blacher , Agnes Noel

The enhancement of the inherently weak optical activity of solvated molecules by superchiral fields, crucial for detecting their chirality, is a research frontier of photonics and the basis of novel chiroptical detection schemes. Here, we…

Coherent control of bound state processes via the interfering overlapping resonances scenario [Christopher et al., J. Chem. Phys. 123, 064313 (2006)] is developed to control intramolecular vibrational redistribution (IVR). The approach is…

Quantum Physics · Physics 2007-05-23 D. Gerbasi , A. S. Sanz , P. S. Christopher , M. Shapiro , P. Brumer

The influence of fast vibrations on energy transfer and conversion in natural molecular aggregates is an issue of central interest. This article shows the important role of high-energy quantized vibrations and their non-equilibrium dynamics…

Biological Physics · Physics 2013-01-30 Avinash Kolli , Edward J. O'Reilly , Gregory D. Scholes , Alexandra Olaya-Castro

Although ultrafast laser materials processing has advanced at a breakneck pace over the last two decades, most applications have been developed with laser pulses at near-IR or visible wavelengths. Recent progress in mid-infrared (MIR)…

Materials Science · Physics 2020-01-08 Kevin Werner , Vitaly Gruzdev , Noah Talisa , Kyle Kafka , Drake Austin , Carl M. Liebig , Enam Chowdhury

We consider a multi-cell massive multiple-input-multiple-output (MIMO) system with correlated Rayleigh fading channels, where pilot reuse is permitted within each cell (to reduce pilot overhead), and each base station (BS) utilizes…

Information Theory · Computer Science 2025-07-08 Masoud Elyasi , Azadeh Vosoughi

Absolute quantity imaging of biomolecules on a single cell level is critical for measurement assurance in biosciences and bioindustries. While infrared (IR) transmission microscopy is a powerful label-free imaging modality capable of…

Quantitative Methods · Quantitative Biology 2024-03-29 Yow-Ren Chang , Seong-Min Kim , Young Jong Lee

Active matter systems evade the constraints of thermal equilibrium, leading to the emergence of intriguing collective behavior. A paradigmatic example is given by motor-filament mixtures, where the motion of motor proteins drives alignment…

Soft Condensed Matter · Physics 2024-09-11 Filippo De Luca , Ivan Maryshev , Erwin Frey

A coherent control scheme for the population distribution in the vibrational states of nonpolar molecules is proposed. Our theoretical analysis and results of numerical simulations for the interaction of the hydrogen molecular ion in its…

Quantum Physics · Physics 2011-02-17 A. Picón , J. Biegert , A. Jaron-Becker , A. Becker

Wide-field mid-infrared photothermal (MIP) imaging offers rapid labelfree chemical contrast for biomedical and polymer analysis. However, its field of view (FOV) is limited by the pulse intensity of conventional infrared lasers. Here, we…

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