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Large language models (LLMs) show promise in drafting responses to patient portal messages, yet their integration into clinical workflows raises various concerns, including whether they would actually save clinicians time and effort in…

Computation and Language · Computer Science 2026-01-19 Parker Seegmiller , Joseph Gatto , Sarah E. Greer , Ganza Belise Isingizwe , Rohan Ray , Timothy E. Burdick , Sarah Masud Preum

Large Language Models (LLMs) possess substantial reasoning capabilities and are increasingly applied to optimization tasks, particularly in synergy with evolutionary computation. However, while recent surveys have explored specific aspects…

Neural and Evolutionary Computing · Computer Science 2026-01-08 Yisong Zhang , Ran Cheng , Guoxing Yi , Kay Chen Tan

The rapid advancements in large Language models (LLMs) have significantly enhanced their reasoning capabilities, driven by various strategies such as multi-agent collaboration. However, unlike the well-established performance improvements…

Artificial Intelligence · Computer Science 2026-04-23 Zihan Chen , Song Wang , Zhen Tan , Xingbo Fu , Zhenyu Lei , Peng Wang , Huan Liu , Cong Shen , Jundong Li

With the introduction of ChatGPT, Large Language Models (LLMs) have received enormous attention in healthcare. Despite their potential benefits, researchers have underscored various ethical implications. While individual instances have…

Computers and Society · Computer Science 2024-07-09 Joschka Haltaufderheide , Robert Ranisch

At the heart of radiological practice is the challenge of integrating complex imaging data with clinical information to produce actionable insights. Nuanced application of language is key for various activities, including managing requests,…

Large language models (LLMs) are having transformative impacts across a wide range of scientific fields, particularly in the biomedical sciences. Just as the goal of Natural Language Processing is to understand sequences of words, a major…

Genomics · Quantitative Biology 2024-09-24 Gonzalo Benegas , Chengzhong Ye , Carlos Albors , Jianan Canal Li , Yun S. Song

Recent advances in artificial intelligence, particularly large language models LLMs, have shown promising capabilities in transforming rare disease research. This survey paper explores the integration of LLMs in the analysis of rare…

Computation and Language · Computer Science 2025-05-26 Valentina Carbonari , Pierangelo Veltri , Pietro Hiram Guzzi

The emergence of advanced reasoning capabilities in Large Language Models (LLMs) marks a transformative development in healthcare applications. Beyond merely expanding functional capabilities, these reasoning mechanisms enhance decision…

Artificial Intelligence · Computer Science 2025-08-27 Armin Berger , Sarthak Khanna , David Berghaus , Rafet Sifa

The growing need to integrate information from a large number of diverse sources poses significant scalability challenges for data integration systems. These systems often rely on manually written schema mappings, which are complex,…

Databases · Computer Science 2025-06-02 Christopher Buss , Mahdis Safari , Arash Termehchy , Stefan Lee , David Maier

Large language models (LLMs) have recently demonstrated their potential in clinical applications, providing valuable medical knowledge and advice. For example, a large dialog LLM like ChatGPT has successfully passed part of the US medical…

Computer Vision and Pattern Recognition · Computer Science 2023-02-15 Sheng Wang , Zihao Zhao , Xi Ouyang , Qian Wang , Dinggang Shen

In many scientific fields, large language models (LLMs) have revolutionized the way text and other modalities of data (e.g., molecules and proteins) are handled, achieving superior performance in various applications and augmenting the…

Computation and Language · Computer Science 2024-10-01 Yu Zhang , Xiusi Chen , Bowen Jin , Sheng Wang , Shuiwang Ji , Wei Wang , Jiawei Han

Large language models (LLMs) have demonstrated great potential for domain-specific applications, such as the law domain. However, recent disputes over GPT-4's law evaluation raise questions concerning their performance in real-world legal…

Computation and Language · Computer Science 2023-10-19 Ruihao Shui , Yixin Cao , Xiang Wang , Tat-Seng Chua

Background: Recent advancements in large language models (LLMs) offer potential benefits in healthcare, particularly in processing extensive patient records. However, existing benchmarks do not fully assess LLMs' capability in handling…

Large language models (LLMs) have shown impressive potential in helping with numerous medical challenges. Deploying LLMs in high-stakes applications such as medicine, however, brings in many concerns. One major area of concern relates to…

Computation and Language · Computer Science 2025-04-15 Hamed Fayyaz , Raphael Poulain , Rahmatollah Beheshti

Large Language Models (LLMs) have remarkable capabilities across NLP tasks. However, their performance in multilingual contexts, especially within the mental health domain, has not been thoroughly explored. In this paper, we evaluate…

Computation and Language · Computer Science 2026-02-03 Nishat Raihan , Sadiya Sayara Chowdhury Puspo , Ana-Maria Bucur , Stevie Chancellor , Marcos Zampieri

Large language models (LLMs) are a class of language models that have demonstrated outstanding performance across a range of natural language processing (NLP) tasks and have become a highly sought-after research area, because of their…

Digital Libraries · Computer Science 2023-04-06 Lizhou Fan , Lingyao Li , Zihui Ma , Sanggyu Lee , Huizi Yu , Libby Hemphill

This study reviewed the use of Large Language Models (LLMs) in healthcare, focusing on their training corpora, customization techniques, and evaluation metrics. A systematic search of studies from 2021 to 2024 identified 61 articles. Four…

Computation and Language · Computer Science 2025-02-18 Shuqi Yang , Mingrui Jing , Shuai Wang , Jiaxin Kou , Manfei Shi , Weijie Xing , Yan Hu , Zheng Zhu

Ontology matching (OM) plays a key role in enabling data interoperability and knowledge sharing, but it remains challenging due to the need for large training datasets and limited vocabulary processing in machine learning approaches.…

Information Retrieval · Computer Science 2025-03-28 Maria Taboada , Diego Martinez , Mohammed Arideh , Rosa Mosquera

The validity of medical studies based on real-world clinical data, such as observational studies, depends on critical assumptions necessary for drawing causal conclusions about medical interventions. Many published studies are flawed…

Artificial Intelligence · Computer Science 2024-07-30 Ahmed Alaa , Rachael V. Phillips , Emre Kıcıman , Laura B. Balzer , Mark van der Laan , Maya Petersen

The proliferation of Large Language Models (LLMs) in high-stakes applications such as medical (self-)diagnosis and preliminary triage raises significant ethical and practical concerns about the effectiveness, appropriateness, and possible…

Computers and Society · Computer Science 2025-06-18 Bonam Mingole , Aditya Majumdar , Firdaus Ahmed Choudhury , Jennifer L. Kraschnewski , Shyam S. Sundar , Amulya Yadav