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Large Language Models (LLMs), originally developed for natural language processing (NLP), have demonstrated the potential to generalize across modalities and domains. With their in-context learning (ICL) capabilities, LLMs can perform…

Artificial Intelligence · Computer Science 2025-08-26 Nikolaos Pavlidis , Vasilis Perifanis , Symeon Symeonidis , Pavlos S. Efraimidis

Although Large Language Models (LLMs) have shown promising performance in healthcare-related applications, their deployment in the medical domain poses unique challenges of ethical, regulatory, and technical nature. In this study, we employ…

Computers and Society · Computer Science 2025-01-22 Giorgia Carra , Bogdan Kulynych , François Bastardot , Daniel E. Kaufmann , Noémie Boillat-Blanco , Jean Louis Raisaro

This paper explores the potential opportunities, risks, and challenges associated with the use of large language models (LLMs) in sports science and medicine. LLMs are large neural networks with transformer style architectures trained on…

Computation and Language · Computer Science 2023-05-09 Mark Connor , Michael O'Neill

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

Computation and Language · Computer Science 2025-05-21 Kevin Wu , Eric Wu , Rahul Thapa , Kevin Wei , Angela Zhang , Arvind Suresh , Jacqueline J. Tao , Min Woo Sun , Alejandro Lozano , James Zou

Large Language Models (LLMs) have shown promise in clinical decision support, yet their application to triage remains underexplored. We systematically investigate the capabilities of LLMs in emergency department triage through two key…

Artificial Intelligence · Computer Science 2025-08-06 Joseph Lee , Tianqi Shang , Jae Young Baik , Duy Duong-Tran , Shu Yang , Lingyao Li , Li Shen

We present Clinical Prediction with Large Language Models (CPLLM), a method that involves fine-tuning a pre-trained Large Language Model (LLM) for clinical disease and readmission prediction. We utilized quantization and fine-tuned the LLM…

Computation and Language · Computer Science 2024-05-03 Ofir Ben Shoham , Nadav Rappoport

Large-language models have recently demonstrated impressive zero-shot capabilities in a variety of natural language tasks such as summarization, dialogue generation, and question-answering. Despite many promising applications in clinical…

Large language models (LLMs) are a class of artificial intelligence models based on deep learning, which have great performance in various tasks, especially in natural language processing (NLP). Large language models typically consist of…

Quantitative Methods · Quantitative Biology 2025-02-04 Jiajia Liu , Mengyuan Yang , Yankai Yu , Haixia Xu , Tiangang Wang , Kang Li , Xiaobo Zhou

Text embeddings have become an essential part of a variety of language applications. However, methods for interpreting, exploring and reversing embedding spaces are limited, reducing transparency and precluding potentially valuable…

Computation and Language · Computer Science 2026-01-27 Brian Ondov , Chia-Hsuan Chang , Yujia Zhou , Mauro Giuffrè , Hua Xu

In the past year, there has been a growing trend in applying Large Language Models (LLMs) to the field of medicine, particularly with the advent of advanced language models such as ChatGPT developed by OpenAI. However, there is limited…

Computation and Language · Computer Science 2024-02-27 Fujian Jia , Xin Liu , Lixi Deng , Jiwen Gu , Chunchao Pu , Tunan Bai , Mengjiang Huang , Yuanzhi Lu , Kang Liu

The use of large language models (LLMs) for qualitative analysis is gaining attention in various fields, including software engineering, where qualitative methods are essential for understanding human and social factors. This study aimed to…

Software Engineering · Computer Science 2025-03-11 Matheus de Morais Leça , Lucas Valença , Reydne Santos , Ronnie de Souza Santos

Test-time scaling has emerged as a powerful technique for enhancing the reasoning capabilities of large language models. However, its effectiveness in medical reasoning remains uncertain, as the medical domain fundamentally differs from…

Computation and Language · Computer Science 2026-02-19 Xiaoke Huang , Juncheng Wu , Hui Liu , Xianfeng Tang , Yuyin Zhou

Large language models (LLMs) are introducing a paradigm shift in molecular discovery by enabling text-guided interaction with chemical spaces through natural language, symbolic notations, with emerging extensions to incorporate multi-modal…

Machine Learning · Computer Science 2025-05-23 Ziqing Wang , Kexin Zhang , Zihan Zhao , Yibo Wen , Abhishek Pandey , Han Liu , Kaize Ding

As large language models (LLMs) are deployed in high-stakes domains like healthcare, understanding how well their decision-making aligns with human preferences and values becomes crucial, especially when we recognize that there is no single…

Computation and Language · Computer Science 2024-10-01 Isaac Kohane

Unlocking the potential of Large Language Models (LLMs) in data classification represents a promising frontier in natural language processing. In this work, we evaluate the performance of different LLMs in comparison with state-of-the-art…

Computation and Language · Computer Science 2025-01-16 Arina Kostina , Marios D. Dikaiakos , Dimosthenis Stefanidis , George Pallis

With the increasing application of large language models (LLMs) in the medical domain, evaluating these models' performance using benchmark datasets has become crucial. This paper presents a comprehensive survey of various benchmark…

Large Language Models (LLMs) excel in handling general knowledge tasks, yet they struggle with user-specific personalization, such as understanding individual emotions, writing styles, and preferences. Personalized Large Language Models…

Artificial Intelligence · Computer Science 2025-09-23 Jiahong Liu , Zexuan Qiu , Zhongyang Li , Quanyu Dai , Wenhao Yu , Jieming Zhu , Minda Hu , Menglin Yang , Tat-Seng Chua , Irwin King

Large language models (LLMs) have been increasingly adopted to support patients' healthcare-seeking in recent years. While prior patient-centered studies have examined the capabilities and experience of LLM-based tools in specific…

Human-Computer Interaction · Computer Science 2026-02-25 Yancheng Cao , Yishu Ji , Chris Yue Fu , Sahiti Dharmavaram , Meghan Turchioe , Natalie C Benda , Lena Mamykina , Yuling Sun , Xuhai "Orson" Xu

Large language models (LLMs) show promise for supporting clinicians in diagnostic communication by generating explanations and guidance for patients. Yet their ability to produce outputs that are both understandable and empathetic remains…

Computation and Language · Computer Science 2025-11-04 Jianzhou Yao , Shunchang Liu , Guillaume Drui , Rikard Pettersson , Alessandro Blasimme , Sara Kijewski

Large language models (LLMs) are increasingly utilized in healthcare applications. However, their deployment in clinical practice raises significant safety concerns, including the potential spread of harmful information. This study…

Cryptography and Security · Computer Science 2025-03-05 Hang Zhang , Qian Lou , Yanshan Wang
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