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While micro-CT systems are instrumental in preclinical research, clinical micro-CT imaging has long been desired with cochlear implantation as a primary example. The structural details of the cochlear implant and the temporal bone require a…

This article is intended to supplement our 2015 paper in Medical Physics titled "Noise properties of CT images reconstructed by use of constrained total-variation, data-discrepancy minimization", in which ordered subsets methods were…

Medical Physics · Physics 2016-03-30 Sean Rose , Martin S. Andersen , Emil Y. Sidky , Xiaochuan Pan

Image guidance for minimally invasive interventions is usually performed by acquiring fluoroscopic images using a C-arm system. However, the projective data provide only limited information about the spatial structure and position of…

Purpose: We develop an iterative image-reconstruction algorithm for application to low-intensity computed tomography (CT) projection data, which is based on constrained, total-variation (TV) minimization. The algorithm design focuses on…

Medical Physics · Physics 2015-05-20 Emil Y. Sidky , Yuval Duchin , Christer Ullberg , Xiaochuan Pan

Reconstructing an image from its Radon transform is a fundamental computed tomography (CT) task arising in applications such as X-ray scans. In many practical scenarios, a full 180-degree scan is not feasible, or there is a desire to reduce…

Computer Vision and Pattern Recognition · Computer Science 2025-02-20 Ilmari Vahteristo , Zhi-Song Liu , Andreas Rupp

By the ALARA (As Low As Reasonably Achievable) principle, ultra-low-dose CT reconstruction is a holy grail to minimize cancer risks and genetic damages, especially for children. With the development of medical CT technologies, the iterative…

Image and Video Processing · Electrical Eng. & Systems 2021-06-21 Weiwen Wu , Chuang Niu , Shadi Ebrahimian , Hengyong Yu , Mannu Kalra , Ge Wang

Total variation (TV) regularization is a popular reconstruction method for ill-posed imaging problems, and particularly useful for applications with piecewise constant targets. However, using TV for medical cone-beam computed X-ray…

Medical Physics · Physics 2024-12-11 Alexander Meaney , Mikael A. K. Brix , Miika T. Nieminen , Samuli Siltanen

In inertial confinement fusion (ICF), X-ray radiography is a critical diagnostic for measuring implosion dynamics, which contains rich 3D information. Traditional methods for reconstructing 3D volumes from 2D radiographs, such as filtered…

Traditional X-ray computed tomography (CT) scanning strategies typically select projection angles uniformly and allocate dose equally. In practice, however, CT scans often need to be fast, radiation-efficient, and adaptive. Sparse-view…

Medical Physics · Physics 2026-04-24 Tianyuan Wang , Daniël M. Pelt , Felix Lucka , Tristan van Leeuwen , K. Joost Batenburg

An image or volume of interest in positron emission tomography (PET) is reconstructed from pairs of gamma rays emitted from a radioactive substance. Many image reconstruction methods are based on estimation of pixels or voxels on some…

Signal Processing · Electrical Eng. & Systems 2019-06-18 Azra Tafro , Damir Seršić , Ana Sović Kržić

This paper introduces an innovative methodology for producing high-quality 3D lung CT images guided by textual information. While diffusion-based generative models are increasingly used in medical imaging, current state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Yanwu Xu , Li Sun , Wei Peng , Shuyue Jia , Katelyn Morrison , Adam Perer , Afrooz Zandifar , Shyam Visweswaran , Motahhare Eslami , Kayhan Batmanghelich

Computed Tomography (CT) is a widely utilized imaging modality in clinical settings. Using densely acquired rotational X-ray arrays, CT can capture 3D spatial features. However, it is confronted with challenged such as significant time…

Image and Video Processing · Electrical Eng. & Systems 2025-07-16 Duoyou Chen , Yunqing Chen , Can Zhang , Zhou Wang , Cheng Chen , Ruoxiu Xiao

Volumetric rendering of Computed Tomography (CT) scans is crucial for visualizing complex 3D anatomical structures in medical imaging. Current high-fidelity approaches, especially neural rendering techniques, require time-consuming…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Zhongpai Gao , Meng Zheng , Benjamin Planche , Anwesa Choudhuri , Terrence Chen , Ziyan Wu

In image-guided radiotherapy (IGRT), four-dimensional cone-beam computed tomography (4D-CBCT) is critical for assessing tumor motion during a patients breathing cycle prior to beam delivery. However, generating 4D-CBCT images with…

Medical Physics · Physics 2025-01-09 Yabo Fu , Hao Zhang , Weixing Cai , Huiqiao Xie , Licheng Kuo , Laura Cervino , Jean Moran , Xiang Li , Tianfang Li

Spectral computed tomography (CT) has attracted much attention in radiation dose reduction, metal artifacts removal, tissue quantification and material discrimination. The x-ray energy spectrum is divided into several bins, each…

Image and Video Processing · Electrical Eng. & Systems 2021-08-26 Weiwen Wu , Dianlin Hu , Chuang Niu , Lieza Vanden Broeke , Anthony P. H. Butler , Peng Cao , James Atlas , Alexander Chernoglazov , Varut Vardhanabhuti , Ge Wang

We integrate a small and portable medical x-ray device with mechanical testing equipment to enable in-situ, non-invasive measurements of a granular material's response to mechanical loading. We employ an orthopedic C-arm as the x-ray source…

Accurate 3D dental imaging is vital for diagnosis and treatment planning, yet CBCT's high radiation dose and cost limit its accessibility. Reconstructing 3D volumes from a single low-dose panoramic X-ray is a promising alternative but…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Wen Ma , Jiaxiang Liu , Zikai Xiao , Ziyang Wang , Feng Yang , Zuozhu Liu

Chest X-ray radiography (CXR) is an essential medical imaging technique for disease diagnosis. However, as 2D projectional images, CXRs are limited by structural superposition and hence fail to capture 3D anatomies. This limitation makes…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Zefan Yang , Ge Wang , James Hendler , Mannudeep K. Kalra , Pingkun Yan

Modern tomography involves gathering projection data from multiple directions and feeding them into a software algorithm for tomographic reconstruction. We focus our study on image reconstruction from Radon data in the setting of…

Numerical Analysis · Mathematics 2014-12-19 Maria Angela Narduzzo

Commercial iterative reconstruction techniques on modern CT scanners target radiation dose reduction but there are lingering concerns over their impact on image appearance and low contrast detectability. Recently, machine learning,…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Hongming Shan , Atul Padole , Fatemeh Homayounieh , Uwe Kruger , Ruhani Doda Khera , Chayanin Nitiwarangkul , Mannudeep K. Kalra , Ge Wang