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Access to high-quality datasets in the medical industry limits machine learning model performance. To address this issue, we propose a Denoising Diffusion Probabilistic Model (DDPM) combined with a UNet architecture for X-ray image…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Praveen Mahaulpatha , Thulana Abeywardane , Tomson George

The success of Deep Learning applications critically depends on the quality and scale of the underlying training data. Generative adversarial networks (GANs) can generate arbitrary large datasets, but diversity and fidelity are limited,…

Background: Daily or weekly cone-beam computed tomography (CBCT) scans are commonly used for accurate patient positioning during the image-guided radiotherapy (IGRT) process, making it an ideal option for adaptive radiotherapy (ART)…

Pathological brain lesions exhibit diverse appearance in brain images, in terms of intensity, texture, shape, size, and location. Comprehensive sets of data and annotations are difficult to acquire. Therefore, unsupervised anomaly detection…

The scarcity and complexity of voxel-level annotations in 3D medical imaging present significant challenges, particularly due to the domain gap between labeled datasets from well-resourced centers and unlabeled datasets from less-resourced…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Haifan Gong , Yitao Wang , Yihan Wang , Jiashun Xiao , Xiang Wan , Haofeng Li

Magnetic resonance (MR) imaging, including cardiac MR, is prone to domain shift due to variations in imaging devices and acquisition protocols. This challenge limits the deployment of trained AI models in real-world scenarios, where…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Xin Ci Wong , Duygu Sarikaya , Kieran Zucker , Marc De Kamps , Nishant Ravikumar

Denoising diffusion models have recently achieved state-of-the-art performance in many image-generation tasks. They do, however, require a large amount of computational resources. This limits their application to medical tasks, where we…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Florentin Bieder , Julia Wolleb , Alicia Durrer , Robin Sandkühler , Philippe C. Cattin

The purpose of this study is to present and compare three denoising diffusion probabilistic models (DDPMs) that generate 3D $T_1$-weighted MRI human brain images. Three DDPMs were trained using 80,675 image volumes from 42,406 subjects…

Image and Video Processing · Electrical Eng. & Systems 2025-11-03 Samuel W. Remedios , Aaron Carass , Jerry L. Prince , Blake E. Dewey

This study aims to improve photon counting CT (PCCT) image resolution using denoising diffusion probabilistic models (DDPM). Although DDPMs have shown superior performance when applied to various computer vision tasks, their effectiveness…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Chuang Niu , Christopher Wiedeman , Mengzhou Li , Jonathan S Maltz , Ge Wang

This paper introduces an approach, named DFormer, for universal image segmentation. The proposed DFormer views universal image segmentation task as a denoising process using a diffusion model. DFormer first adds various levels of Gaussian…

Computer Vision and Pattern Recognition · Computer Science 2023-06-09 Hefeng Wang , Jiale Cao , Rao Muhammad Anwer , Jin Xie , Fahad Shahbaz Khan , Yanwei Pang

Large-scale, big-variant, high-quality data are crucial for developing robust and successful deep-learning models for medical applications since they potentially enable better generalization performance and avoid overfitting. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Zheyuan Zhang , Lanhong Yao , Bin Wang , Debesh Jha , Gorkem Durak , Elif Keles , Alpay Medetalibeyoglu , Ulas Bagci

Anatomical atlases are widely used for population studies and analysis. Conditional atlases target a specific sub-population defined via certain conditions, such as demographics or pathologies, and allow for the investigation of…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Sophie Starck , Vasiliki Sideri-Lampretsa , Bernhard Kainz , Martin J. Menten , Tamara T. Mueller , Daniel Rueckert

Deep learning techniques for anatomical landmark localization (ALL) have shown great success, but their reliance on large annotated datasets remains a problem due to the tedious and costly nature of medical data acquisition and annotation.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Arnela Hadzic , Lea Bogensperger , Simon Johannes Joham , Martin Urschler

Low-dose Computed Tomography (LDCT) reconstruction is an important task in medical image analysis. Recent years have seen many deep learning based methods, proved to be effective in this area. However, these methods mostly follow a…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Runyi Li

The Segment Anything Model (SAM) exhibits a capability to segment a wide array of objects in natural images, serving as a versatile perceptual tool for various downstream image segmentation tasks. In contrast, medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Yizhe Zhang , Tao Zhou , Shuo Wang , Ye Wu , Pengfei Gu , Danny Z. Chen

Diffusion models form an important class of generative models today, accounting for much of the state of the art in cutting edge AI research. While numerous extensions beyond image and video generation exist, few of such approaches address…

Machine Learning · Computer Science 2025-04-30 Hao Luan , See-Kiong Ng , Chun Kai Ling

Image generation is a prevailing technique for clinical data augmentation for advancing diagnostic accuracy and reducing healthcare disparities. Diffusion Model (DM) has become a leading method in generating synthetic medical images, but it…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Ruichen Zhang , Yuguang Yao , Zhen Tan , Zhiming Li , Pan Wang , Huan Liu , Jingtong Hu , Sijia Liu , Tianlong Chen

Weakly supervised medical image segmentation (MIS) using generative models is crucial for clinical diagnosis. However, the accuracy of the segmentation results is often limited by insufficient supervision and the complex nature of medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Zhihao Shuai , Yinan Chen , Shunqiang Mao , Yihan Zho , Xiaohong Zhang

Deep neural networks have been extensively applied in the medical domain for various tasks, including image classification, segmentation, and landmark detection. However, their application is often hindered by data scarcity, both in terms…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Roberto Di Via , Francesca Odone , Vito Paolo Pastore

In recent years, Denoising Diffusion Models have demonstrated remarkable success in generating semantically valuable pixel-wise representations for image generative modeling. In this study, we propose a novel end-to-end framework, called…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Zhaohu Xing , Liang Wan , Huazhu Fu , Guang Yang , Lei Zhu