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Modeling the spread of COVID-19 is crucial for informing public health policy. All models for COVID-19 epidemiology rely on parameters describing the dynamics of the infection process. The meanings of epidemiological parameters like R_0,…

Other Quantitative Biology · Quantitative Biology 2020-07-13 Yinon M. Bar-On , Ron Sender , Avi I. Flamholz , Rob Phillips , Ron Milo

Understanding the dynamics of the spread of diseases within populations is critical for effective public health interventions. We extend the classical SIR model by incorporating additional complexities such as the introduction of a cure and…

Populations and Evolution · Quantitative Biology 2025-10-30 Daniel Perkins , Davis Hunter , Drake Brown , Trevor Garrity , Wyatt Pochman

The COVID-19 pandemic has led to significant changes in how people are currently living their lives. To determine how to best reduce the effects of the pandemic and start reopening societies, governments have drawn insights from…

Other Quantitative Biology · Quantitative Biology 2020-09-08 Heather Z. Brooks , Unchitta Kanjanasaratool , Yacoub H. Kureh , Mason A. Porter

Human to human transmissible infectious diseases spread in a population using human interactions as its transmission vector. The early stages of such an outbreak can be modeled by a graph whose edges encode these interactions between…

Populations and Evolution · Quantitative Biology 2020-06-11 Goncalo Oliveira

The spread of infectious diseases is often influenced by human mobility across different geographical regions. Although numerous studies have investigated how diseases like SARS and COVID-19 spread from China to various global locations,…

Social and Information Networks · Computer Science 2025-05-22 Md. Arquam , Suchi Kumari , Utkarsh Tiwari , Mohammad Al-saffar

We consider a model for an epidemic in a population that occupies geographically distinct locations. The disease is spread within subpopulations by contacts between infective and susceptible individuals, and is spread between subpopulations…

Probability · Mathematics 2016-02-15 R. McVinish , P. K. Pollett , A. Shausan

The COVID-19 disease has forced countries to make a considerable collaborative effort between scientists and governments to provide indicators to suitable follow-up the pandemic's consequences. Mathematical modeling plays a crucial role in…

Populations and Evolution · Quantitative Biology 2020-12-29 Patricio Cumsille , Oscar Rojas-Díaz , Pablo Moisset de Espanés

Accurate numbers are needed to understand and predict viral dynamics. Curation of high-quality literature values for the infectious period duration or household secondary attack rate, for example, is especially pressing currently because…

Other Quantitative Biology · Quantitative Biology 2020-07-10 Yinon M. Bar-On , Ron Sender , Avi I. Flamholz , Rob Phillips , Ron Milo

Attempts to control the epidemic spread of COVID19 in the different countries often involve imposing restrictions to the mobility of citizens. Recent examples demonstrate that the effectiveness of these policies strongly depends on the…

Physics and Society · Physics 2020-07-10 Alejandro Carballosa , Mariamo Mussa-Juane , Alberto P. Muñuzuri

The analysis of contagion-diffusion processes in metapopulations is a powerful theoretical tool to study how mobility influences the spread of communicable diseases. Nevertheless, many metapopulation approaches use indistinguishable agents…

Physics and Society · Physics 2022-04-20 Pablo Valgañón , David Soriano-Paños , Alex Arenas , Jesús Gómez-Gardeñes

The ongoing COVID-19 pandemic calls for a multi-faceted public health response comprising complementary interventions to control the spread of the disease while vaccines and therapies are developed. Many of these interventions need to be…

Applications · Statistics 2020-08-24 Andres Colubri , Kailash Yadav , Abhishek Jha , Pardis C. Sabeti

Nowcasting and forecasting of epidemic spreading rely on incidence series of reported cases to derive the fundamental epidemiological parameters for a given pathogen. Two relevant drawbacks for predictions are the unknown fractions of…

Populations and Evolution · Quantitative Biology 2022-08-31 Guilherme S. Costa , Wesley Cota , Silvio C. Ferreira

Infectious or contagious diseases can be transmitted from one person to another through social contact networks. In today's interconnected global society, such contagion processes can cause global public health hazards, as exemplified by…

Social and Information Networks · Computer Science 2020-07-30 Anirban Dasgupta , Srijan Sengupta

The widespread, and in many countries unprecedented, use of non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic has highlighted the need for mathematical models which can estimate the impact of these measures while…

Susceptible-Invective-Recovered (SIR) mathematical models are in high demand due to the COVID-19 pandemic. They are used in their standard formulation, or through the many variants, trying to fit and hopefully predict the number of new…

Populations and Evolution · Quantitative Biology 2020-05-19 Ben-Hur Francisco Cardoso , Sebastián Gonçalves

One of the key indicators used in tracking the evolution of an infectious disease isthe reproduction number. This quantity is usually computed using the reportednumber of cases, but ignoring that many more individuals may be infected…

Populations and Evolution · Quantitative Biology 2020-09-11 Andrea De Simone , Marco Piangerelli

Within a short period of time, COVID-19 grew into a world-wide pandemic. Transmission by pre-symptomatic and asymptomatic viral carriers rendered intervention and containment of the disease extremely challenging. Based on reported infection…

Populations and Evolution · Quantitative Biology 2021-02-24 Liang Tian , Xuefei Li , Fei Qi , Qian-Yuan Tang , Viola Tang , Jiang Liu , Zhiyuan Li , Xingye Cheng , Xuanxuan Li , Yingchen Shi , Haiguang Liu , Lei-Han Tang

Compartmental models are widely adopted to describe and predict the spreading of infectious diseases. The unknown parameters of such models need to be estimated from the data. Furthermore, when some of the model variables are not…

Physics and Society · Physics 2021-01-18 Luca Gallo , Mattia Frasca , Vito Latora , Giovanni Russo

Epidemiological models describe the spread of an infectious disease within a population. They capture microscopic details on how the disease is passed on among individuals in various different ways, while making predictions about the state…

Populations and Evolution · Quantitative Biology 2024-02-27 Stefan Hohenegger , Francesco Sannino

This article reviews quantitative methods to estimate the basic reproduction number of pandemic influenza, a key threshold quantity to help determine the intensity of interventions required to control the disease. Although it is difficult…

Populations and Evolution · Quantitative Biology 2009-11-13 Gerardo Chowell , Hiroshi Nishiura
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