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The escalating cost, extended timelines, and low success rates in pharmaceutical research demand a fundamental rethinking of biotechnology R&D infrastructure. This chapter introduces the concept of the AI-Integrated Biotechnology Hub, a…

Physics and Society · Physics 2025-10-07 Alex Zhavoronkov , Chuen Yan Leung

With the increasing prevalence of chiplet systems in high-performance computing applications, the number of design options has increased dramatically. Instead of chips defaulting to a single die design, now there are options for 2.5D and 3D…

Hardware Architecture · Computer Science 2025-03-21 Alexander Graening , Jonti Talukdar , Saptadeep Pal , Krishnendu Chakrabarty , Puneet Gupta

The development and first applications of a new periodic energy decomposition analysis (pEDA) scheme for extended systems based on the Kohn-Sham approach to density functional theory are described. The pEDA decomposes the binding energy…

Chemical Physics · Physics 2015-05-19 Marc Raupach , Ralf Tonner

Although digital twins have recently emerged as a clear alternative for reliable asset representations, most of the solutions and tools available for the development of digital twins are tailored to specific environments. Furthermore,…

Software Engineering · Computer Science 2023-01-16 Julia Robles , Cristian Martín , Manuel Díaz

As spatial and temporal resolutions of scientific instruments improve, the explosion in the volume of data produced is becoming a key challenge. It can be a critical bottleneck for integration between scientific instruments at the edge and…

Instrumentation and Detectors · Physics 2021-11-03 Kazutomo Yoshii , Rajesh Sankaran , Sebastian Strempfer , Maksim Levental , Mike Hammer , Antonino Miceli

An ideal software system in computer graphics should be a combination of innovative ideas, solid software engineering and rapid development. However, in reality these requirements are seldom met simultaneously. In this paper, we present…

Graphics · Computer Science 2018-04-26 Yuanming Hu

Open-source AI is scaling rapidly, and model hubs now host millions of artifacts. Each foundation model can spawn large numbers of fine-tunes, adapters, quantizations, merges, and forks. We take the position that compute efficiency alone is…

Emerging Technologies · Computer Science 2026-05-06 Shaina Raza , Iuliia Zarubiieva , Ahmed Y. Radwan , Nate Lesperance , Deval Pandya , Sedef Akinli Kocak , Graham W. Taylor

Design spaces serve as a conceptual framework that enables designers to explore feasible solutions through the selection and combination of design elements. However, effective decision-making remains heavily dependent on the designer's…

Human-Computer Interaction · Computer Science 2025-06-13 Chuer Chen , Xiaoke Yan , Xiaoyu Qi , Nan Cao

We present Edaq530, a low-cost, compact and easy-to-use digital measurement solution consisting of a thumb-sized USB-to-sensor interface and a measurement software. The solution is fully open-source, our aim being to provide a viable…

Instrumentation and Detectors · Physics 2012-02-23 Katalin Kopasz , Péter Makra , Zoltán Gingl

In the modern semiconductor industry, automatic generation of parameterized and recurring layout structures plays an important role and should be present as a feature in Electronic Design Automation (EDA)-tools. Currently these layout…

Other Computer Science · Computer Science 2016-07-05 Sepideh Alassi , Bertram Winter

We proposes a platform which can generate hardware/software description based on flexible in-struction set architectures (ISAs). The platform takes advantage of the flexibility of field pro-grammable gate array (FPGA) to design many micro…

Logic in Computer Science · Computer Science 2021-05-27 Shih-Yi Yuan , Bo-Yu Zhu

The FAIR (Findable, Accessible, Interoperable, and Reusable) data principles have gained significant attention as a means to enhance data sharing, collaboration, and reuse across various domains. Here, we explore the potential benefits of…

Physics and Society · Physics 2025-06-17 Michael Seitz , Nick Garabedian , Ilia Bagov , Christian Greiner

Despite the fact that computational fluid dynamics (CFD) software is now (relatively) fast and freely available, it is still amazingly difficult to use. Inaccessible software imposes a significant entry barrier on students and junior…

Computational Physics · Physics 2015-10-26 Gabriel D. Weymouth

This paper presents a tool that simplifies quantum software development by unifying circuit design, code generation, and execution within a single cross-platform environment that supports iterative development. Implemented as open source,…

Static Random-Access Memory (SRAM) yield analysis is essential for semiconductor innovation, yet research progress faces a critical challenge: the large gap between simplified academic models and the complexities observed in practice. The…

Hardware Architecture · Computer Science 2025-11-18 Shan Shen , Xingyang Li , Zhuohua Liu , Junhao Ma , Yikai Wang , Yiheng Wu , Yuquan Sun , Wei W. Xing

Object detection on the edge (Edge-OD) is in growing demand thanks to its ever-broad application prospects. However, the development of this field is rigorously restricted by the deployment dilemma of simultaneously achieving high accuracy,…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Chao Wu , Yifan Gong , Liangkai Liu , Mengquan Li , Yushu Wu , Xuan Shen , Zhimin Li , Geng Yuan , Weisong Shi , Yanzhi Wang

Since Estimation of Distribution Algorithms (EDA) were proposed, many attempts have been made to improve EDAs' performance in the context of global optimization. So far, the studies or applications of multivariate probabilistic model based…

Neural and Evolutionary Computing · Computer Science 2011-11-10 Weishan Dong , Tianshi Chen , Peter Tino , Xin Yao

The demand for smartness in embedded systems has been mounting up drastically in the past few years. Embedded system today must address the fundamental challenges introduced by cloud computing and artificial intelligence. KubeEdge [1] is an…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-07-21 Sean Wang , Yuxiao Hu , Jason Wu

Algorithm parallelization to leverage multi-core platforms for improving the efficiency of Electronic Design Automation~(EDA) tools plays a significant role in enhancing the scalability of Integrated Circuit (IC) designs. Logic optimization…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-04-23 Ye Cai , Zonglin Yang , Liwei Ni , Junfeng Liu , Biwei Xie , Xingquan Li

Edge computing has become a popular paradigm where services and applications are deployed at the network edge closer to the data sources. It provides applications with outstanding benefits, including reduced response latency and enhanced…

Networking and Internet Architecture · Computer Science 2022-09-15 Mingjin Zhang , Jiannong Cao , Yuvraj Sahni , Qianyi Chen , Shan Jiang , Tao Wu