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The task of dimensionality reduction and visualization of high-dimensional datasets remains a challenging problem since long. Modern high-throughput technologies produce newer high-dimensional datasets having multiple views with relatively…

Human-Computer Interaction · Computer Science 2023-04-05 Chayan Maitra , Dibyendu B. Seal , Rajat K. De

Motivation: The visualization and analysis of high-dimensional data are essential in biomedical research. There is a need for secure, scalable, and reproducible tools to facilitate data exploration and interpretation. Results: We introduce…

Quantitative Methods · Quantitative Biology 2025-04-15 Xijin Ge

Summary: Biospectrogam is an open-source software for the spectral analysis of DNA and protein sequences. The software can fetch (from NCBI server), import and manage biological data. One can analyze the data using Digital Signal Processing…

Quantitative Methods · Quantitative Biology 2012-10-05 Naman Turakhia , Nilay Chheda , Manish K. Gupta , Ruchin Shah , Jigar Raisinghani

Transport-Based Morphometry (TBM) has emerged as a new framework for 3D medical image analysis. By embedding images into a transport domain via invertible transformations, TBM facilitates effective classification, regression, and other…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Hongyu Kan , Kristofor Pas , Ivan Medri , Naqib Sad Pathan , Natasha Ironside , Shinjini Kundu , Jingjia He , Gustavo Kunde Rohde

PathDB is a Java-based graph database designed for in-memory data loading and querying. By utilizing Regular Path Queries (RPQ) and a closed path algebra, PathDB processes paths through its three main components: the parser, the logical…

Databases · Computer Science 2025-07-04 Roberto García , Renzo Angles , Vicente Rojas , Sebastián Ferrada

Interactive molecular graphics applications facilitate analysis of three dimensional protein structures. Naturally, non-interactive 2-D snapshots of the protein structures do not convey the same level of geometric detail. Several 2-D…

Quantitative Methods · Quantitative Biology 2014-02-24 Francis Bell , Chunyu Zhao , Ahmet Sacan

Tracking single molecules is instrumental for quantifying the transport of molecules and nanoparticles in biological samples, e.g., in brain drug delivery studies. Existing intensity-based localisation methods are not developed for imaging…

JBotSim is a java library that offers basic primitives for prototyping, running, and visualizing distributed algorithms in dynamic networks. With JBotSim, one can implement an idea in minutes and interact with it ({\it e.g. }, add, move, or…

Mathematical Software · Computer Science 2019-09-26 Arnaud Casteigts , Rémi Laplace

The need for fast diagnostic image viewing in zero footprint web applications and the ever increasing image sizes for new modalities such as digital pathology have painfully brought to light that the currently available image compression…

Image and Video Processing · Electrical Eng. & Systems 2020-05-19 Bas Hulsken

Modern bioimage analysis approaches are data hungry, making it necessary for researchers to scavenge data beyond those collected within their (bio)imaging facilities. In addition to scale, bioimaging datasets must be accompanied with…

Image and Video Processing · Electrical Eng. & Systems 2025-12-19 Stefan Dvoretskii , Anwai Archit , Constantin Pape , Josh Moore , Marco Nolden

We present a pipeline for unbiased and robust multimodal registration of neuroimaging modalities with minimal pre-processing. While typical multimodal studies need to use multiple independent processing pipelines, with diverse options and…

Computer Vision and Pattern Recognition · Computer Science 2024-01-26 Adria Casamitjana , Juan Eugenio Iglesias , Raul Tudela , Aida Ninerola-Baizan , Roser Sala-Llonch

In this manuscript, we will introduce a recently developed program GPView, which can be used for wave function analysis and visualization. The wave function analysis module can calculate and generate 3D cubes for various types of molecular…

Chemical Physics · Physics 2020-01-08 Tian Shi , Ping Wang

In this paper, we present BIMS (Biomedical Information Management System). BIMS is a software architecture designed to provide a flexible computational framework to manage the information needs of a wide range of biomedical research…

Software Engineering · Computer Science 2013-03-26 Oscar Mora , Jesús Bisbal

Molecular visualization software has long supported research and education in chemical and structural sciences, but consumer devices constrained to 2D inputs and outputs pose two major challenges: they poorly convey 3D nature, and 3D…

Chemical Physics · Physics 2025-09-05 Luciano A. Abriata

The rapid development of tools for acquisition and storage of information has lead to the formation of enormous medical databases. The large quantity of data definitely surpasses the abilities of humans for efficient usage without…

Information Retrieval · Computer Science 2009-04-03 Petar Kormushev

Currently, a substantial volume of document data exists in an unstructured format, encompassing Portable Document Format (PDF) files and images. Extracting information from these documents presents formidable challenges due to diverse table…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Lei Sheng , Shuai-Shuai Xu

Alterations in nuclear morphology are useful adjuncts and even diagnostic tools used by pathologists in the diagnosis and grading of many tumors, particularly malignant tumors. Large datasets such as TCGA and the Human Protein Atlas, in…

Quantitative Methods · Quantitative Biology 2023-02-06 Mohammad Shifat E Rabbi , Natasha Ironside , John A Ozolek , Rajendra Singh , Liron Pantanowitz , Gustavo K Rohde

In mass spectrometry-based proteomics, experts usually project data onto a single set of reference sequences, overlooking the influence of common haplotypes (combinations of genetic variants inherited together from a parent). We recently…

Genomics · Quantitative Biology 2025-04-10 Jakub Vašíček , Dafni Skiadopoulou , Ksenia G. Kuznetsova , Lukas Käll , Marc Vaudel , Stefan Bruckner

The identification of metabolites from complex biological samples often involves matching experimental mass spectrometry data to signatures of compounds derived from massive chemical databases. However, misidentifications may result due to…

Quantitative Methods · Quantitative Biology 2023-07-11 Christine H. Chang , Bryan J. Killinger , Ryan S. Renslow , Sean M. Colby

Scientific papers use schematic diagrams to communicate methods, workflows, and system structure, yet existing scientific-figure corpora often mix them with plots, screenshots, and photographs and rarely preserve document context. We…

Information Retrieval · Computer Science 2026-05-28 Ling Yue , Tingwen Zhang , Jiaying Wang , Zhen Xu , Shaowu Pan