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We present PyAtoms, an interactive open-source software that rapidly simulates atomic-scale scanning tunneling microscopy (STM) and other scanning probe microscopy (SPM) images of two-dimensional (2D) layered materials, moir\'{e} systems,…

MRI-based medical imaging has become indispensable in modern clinical diagnosis, particularly for brain tumor detection. However, the rapid growth in data volume poses challenges for conventional diagnostic approaches. Although deep…

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Programmable biomolecule-mediated computing is a new computing paradigm as compared to contemporary electronic computing. It employs nucleic acids and analogous biomolecular structures as information-storing and -processing substrates to…

Emerging Technologies · Computer Science 2024-01-30 Jian-Jun Shu , Zi Hian Tan , Qi-Wen Wang , Kian-Yan Yong

Summary: VTX is a molecular visualization software capable to handle most molecular structures and dynamics trajectories file formats. It features a real-time high-performance molecular graphics engine, based on modern OpenGL, optimized for…

In hematology, computational models offer significant potential to improve diagnostic accuracy, streamline workflows, and reduce the tedious work of analyzing single cells in peripheral blood or bone marrow smears. However, clinical…

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Probabilistic graphical models (PGMs) serve as a powerful framework for modeling complex systems with uncertainty and extracting valuable insights from data. However, users face challenges when applying PGMs to their problems in terms of…

Machine Learning · Computer Science 2024-05-29 Jiantong Jiang , Zeyi Wen , Peiyu Yang , Atif Mansoor , Ajmal Mian

Motivation: Peptides have attracted the attention in this century due to their remarkable therapeutic properties. Computational tools are being developed to take advantage of existing information, encapsulating knowledge and making it…

The rise in loosely-structured data available through text, images, and other modalities has called for new ways of querying them. Multimedia Information Retrieval has filled this gap and has witnessed exciting progress in recent years.…

Multimedia · Computer Science 2024-01-31 Giovanni Trappolini , Andrea Santilli , Emanuele Rodolà , Alon Halevy , Fabrizio Silvestri

Cryo-electron tomography enables 3D visualization of cells in a near native state at molecular resolution. The produced cellular tomograms contain detailed information about all macromolecular complexes, their structures, their abundances…

Quantitative Methods · Quantitative Biology 2019-04-30 Min Xu , Elitza I Tocheva , Yi-Wei Chang , Grant J Jensen , Frank Alber

Dynamic programming (DP) is a fundamental and powerful algorithmic paradigm taught in most undergraduate (and many graduate) algorithms classes. DP problems are challenging for many computer science students because they require identifying…

Computers and Society · Computer Science 2024-11-13 David H. Lee , Aditya Prasad , Ramiro Deo-Campo Vuong , Tianyu Wang , Eric Han , David Kempe

We demonstrate NeedleDB, an open-source, deployment-ready database system for answering complex natural language queries over image data. Unlike existing approaches that rely on contrastive-learning embeddings (e.g., CLIP), which degrade on…

Databases · Computer Science 2026-03-31 Mahdi Erfanian , Abolfazl Asudeh

Diffusion bridges (DBs) are a class of diffusion models that enable faster sampling by interpolating between two paired image distributions. Training traditional DBs for image reconstruction requires high-quality reference images, which…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Harry Gao , Weijie Gan , Yuyang Hu , Hongyu An , Ulugbek S. Kamilov

Structure-based protein design has attracted increasing interest, with numerous methods being introduced in recent years. However, a universally accepted method for evaluation has not been established, since the wet-lab validation can be…

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Bayesian Networks (BNs) are used in various fields for modeling, prediction, and decision making. pgmpy is a python package that provides a collection of algorithms and tools to work with BNs and related models. It implements algorithms for…

Machine Learning · Computer Science 2023-04-19 Ankur Ankan , Johannes Textor

The graph database (GDB) is an increasingly common storage model for data involving relationships between entries. Beyond its widespread usage in database industries, the advantages of GDBs indicate a strong potential in constructing…

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In this paper, we introduce fastHDMI, a Python package designed for efficient variable screening in high-dimensional datasets, particularly neuroimaging data. This work pioneers the application of three mutual information estimation methods…

Machine Learning · Statistics 2024-10-15 Kai Yang , Masoud Asgharian , Nikhil Bhagwat , Jean-Baptiste Poline , Celia M. T. Greenwood

Proteins are the main workhorses of biological functions in a cell, a tissue, or an organism. Identification and quantification of proteins in a given sample, e.g. a cell type under normal/disease conditions, are fundamental tasks for the…

Computational Engineering, Finance, and Science · Computer Science 2017-10-10 Ngoc Hieu Tran , Zachariah Levine , Lei Xin , Baozhen Shan , Ming Li

There is a need for open-source libraries in emission tomography that (i) use modern and popular backend code to encourage community contributions and (ii) offer support for the multitude of reconstruction techniques available in recent…

BondGraphTools is a Python library for scripted modelling of complex multi-physics systems. In contrast to existing modelling solutions, BondGraphTools is based upon the well established bond graph methodology, provides a programming…

Systems and Control · Electrical Eng. & Systems 2019-06-27 Peter Cudmore , Peter J. Gawthrop , Michael Pan , Edmund J. Crampin

Genomic data and biomedical imaging data are undergoing exponential growth. However, our understanding of the phenotype-genotype connection linking the two types of data is lagging behind. While there are many types of software that enable…

Genomics · Quantitative Biology 2013-01-09 Andrew T. Oberlin , Dominika A. Jurkovic , Mitchell F. Balish , Iddo Friedberg