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Atomic Force Microscopy (AFM) enables high-resolution surface imaging at the nanoscale, yet the output is often degraded by artifacts introduced by environmental noise, scanning imperfections, and tip-sample interactions. To address this…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Juntao Zhang , Angona Biswas , Jaydeep Rade , Charchit Shukla , Juan Ren , Anwesha Sarkar , Adarsh Krishnamurthy , Aditya Balu

An ongoing challenge in atomic force microscope (AFM) experiments is the quantitative measurement of cantilever motion. The vast majority of AFMs use the optical beam deflection (OBD) method to infer the deflection of the cantilever. The…

Mesoscale and Nanoscale Physics · Physics 2015-05-22 Aleks Labuda , Roger Proksch

An atomic force microscope (AFM) is capable of producing ultra-high resolution measurements of nanoscopic objects and forces. It is an indispensable tool for various scientific disciplines such as molecular engineering, solid-state physics,…

Applications · Statistics 2017-06-28 Bryan Yates , Aleksander Labuda , Martin Lysy

This article reviews the progress of atomic force microscopy (AFM) in ultra-high vacuum, starting with its invention and covering most of the recent developments. Today, dynamic force microscopy allows to image surfaces of conductors…

Materials Science · Physics 2009-11-10 Franz J. Giessibl

The dynamic behavior of AFM is studied taking into account the nonlinear interaction forces between probe and sample. The exerted forces on the free end of micro-beam are simulated with the third degree polynomial. The effect of some…

Applied Physics · Physics 2020-09-15 Sina Eftekhar , Seyyed Mostafa Mousavi Janbeh Sarayi

Conventional dynamic atomic force microscopy (AFM) can be extended to bimodal and multimodal AFM in which the cantilever is simultaneously excited at two ore more resonance frequencies. Such excitation schemes result in one additional…

Mesoscale and Nanoscale Physics · Physics 2014-11-19 Daniel Forchheimer , Stanislav S. Borysov , Daniel Platz , David B. Haviland

Mechanical properties of biological samples have been imaged with a \textit{Force Feedback Microscope}. Force, force gradient and dissipation are measured simultaneously and quantitatively, merely knowing the AFM cantilever spring constant.…

Biological Physics · Physics 2014-05-01 Luca Costa , Mario S Rodrigues , Emily Newman , Chloe Zubieta , Joel Chevrier , Fabio Comin

Atomic Force Microscopy with SideWall (AFM SW) is widely used for nano-scale surface measurements at side surfaces. In the current study, by taking into consideration the effects of sidewall beam and its probe, an analytical method is…

Applied Physics · Physics 2020-09-15 Sina Eftekhar , Seyyed Mostafa Mousavi Janbeh Sarayi

We describe a novel application of atomic force microscopy (AFM) to directly visualize cytoskeletal fibers in human foreskin epithelial cells. The nonionic detergent Triton X-100 in a low concentration was used to remove the membrane,…

Biological Physics · Physics 2007-05-23 T. Berdyyeva , C. D. Woodworth , I. Sokolov

A thorough comprehension of the rheological behavior of polymers during industrial processes is essential for optimizing manufacturing efficiency and product quality. The final properties and behavior of resulting polymer parts are known to…

Using electrostatic coupling between an AFM tip and a metallic surface as a test interaction, we here present the measurement of the force between the tip and the surface, together with the measurement of the interaction stiffness and the…

Mesoscale and Nanoscale Physics · Physics 2014-12-09 Simon Carpentier , Mario S. Rodrigues , Joël Chevrier

A novel method for measuring the surface coverage of randomly distributed cylindrical nanoparticles such as nanorods and nanowires, using atomic force microscopy (AFM), is presented. The method offers several advantages over existing…

Materials Science · Physics 2018-07-12 Francesca Bottacchi , Stefano Bottacchi , Thomas D. Anthopoulos

Atomic Force Microscopy (AFM) has a great potential as a tool to characterize mechanical and morphological properties of living cells; these properties have been shown to correlate with cells' fate and patho-physiological state in view of…

Soft Condensed Matter · Physics 2017-06-21 Luca Puricelli , Massimiliano Galluzzi , Carsten Schulte , Alessandro Podestà , Paolo Milani

Frequency dependent dynamic behavior in Piezoresponse Force Microscopy (PFM) implemented on a beam-deflection atomic force microscope (AFM) is analyzed using a combination of modeling and experimental measurements. The PFM signal comprises…

Materials Science · Physics 2015-06-25 Stephen Jesse , Arthur P. Baddorf , Sergei V. Kalinin

Atomic Force Microscopy (AFM) is a suitable tool to perform tribological characterization of materials down to the nanometer scale. An important aspect in nanofriction measurements of corrugated samples is the local tilt of the surface,…

Condensed Matter · Physics 2017-06-22 A. Podesta' , G. Fantoni , P. Milani

We describe a high-resolution, high-bandwidth technique for determining the local viscoelasticity of soft materials such as polymer gels. Loss and storage shear moduli are determined from the power spectra of thermal fluctuations of…

Soft Condensed Matter · Physics 2009-10-30 F. Gittes , B. Schnurr , P. D. Olmsted , F. C. MacKintosh , C. F. Schmidt

We propose an analytical model for the force-indentation relationship in viscoelastic materials exhibiting a power law relaxation described by an exponent n, where n = 1 represents the standard viscoelastic solid (SLS) model, and n < 1…

Soft Condensed Matter · Physics 2017-02-01 J. S. de Sousa , J. A. C. Santos , E. B. Barros , J. Mendes Filho , L . M. R. Alencar , W. T. Cruz , M. V. Ramos

The functionalization of an Atomic Force Microscope (AFM) cantilever with a colloidal bead is a widely used technique when the geometry between the probe and the sample must be controlled, particularly in force spectroscopy. But some…

Mesoscale and Nanoscale Physics · Physics 2013-05-09 Justine Laurent , Audrey Steinberger , Ludovic Bellon

High-frequency atomic force microscopy has enabled extraordinary new science through large bandwidth, high speed measurements of atomic and molecular structures. However, traditional optical detection schemes restrict the dimensions, and…

Mesoscale and Nanoscale Physics · Physics 2014-03-11 C. Doolin , P. H. Kim , B. D. Hauer , A. J. R MacDonald , J. P Davis

The description of hydrodynamic interactions between a particle and the surrounding liquid, down to the nanometer scale, is of primary importance since confined liquids are ubiquitous in many natural and technological situations. In this…