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Epidemic disease spreading is conventionally often modelled and analyzed by means of rate and diffusion equations, following the paradigms of well-controlled chemical reactions and diffusive dynamics in a test tube. Yet, serious worries…

Physics and Society · Physics 2023-01-03 Klaus Kroy

The SIR model is a three-compartment model of the time development of an epidemic. After normalizing the dependent variables, the model is a system of two non-linear differential equations for the susceptible proportion $S$ and the infected…

Dynamical Systems · Mathematics 2021-04-27 William G. Faris

The time-varying reproduction number ($R_t$) gives an indication of the trajectory of an infectious disease outbreak. Commonly used frameworks for inferring $R_t$ from epidemiological time series include those based on compartmental models…

Controlling and understanding epidemic outbreaks has recently drawn great interest in a large spectrum of research communities. Vaccination is one of the most well-established and effective strategies in order to contain an epidemic. In the…

Social and Information Networks · Computer Science 2023-05-29 Sourin Chatterjee , Ahad N. Zehmakan

In general insurance companies, a correct estimation of liabilities plays a key role due to its impact on management and investing decisions. Since the Financial Crisis of 2007-2008 and the strengthening of regulation, the focus is not only…

Risk Management · Quantitative Finance 2022-05-17 Eduardo Ramos-Pérez , Pablo J. Alonso-González , José Javier Núñez-Velázquez

Epidemiological forecasting from surveillance data is a hard problem and hybridizing mechanistic compartmental models with neural models is a natural direction. The mechanistic structure helps keep trajectories epidemiologically plausible,…

Machine Learning · Computer Science 2026-02-09 Yiqi Su , Ray Lee , Jiaming Cui , Naren Ramakrishnan

The ongoing COVID-19 pandemic is challenging every part of society. From a scientific point of view the first major task is to predict the dynamics of the pandemic, allowing governments to allocate proper resources and measures to fight it,…

Populations and Evolution · Quantitative Biology 2020-09-29 Heinrich Stolz , Dirk Semkat , Peter Grünwald

Compartmental models are popular in the mathematics of epidemiology for their simplicity and wide range of applications. Although they are typically solved as initial value problems for a system of ordinary differential equations, the…

Populations and Evolution · Quantitative Biology 2022-10-12 Eduard Campillo-Funollet , Hayley Wragg , James Van Yperen , Duc-Lam Duong , Anotida Madzvamuse

When an unprecedented infectious disease with high mortality and transmissibility emerges, immediate usage of vaccines or medicines is hardly available. Thus, many health authorities rely on non-pharmaceutical interventions through…

Physics and Society · Physics 2022-01-21 Minsuk Kim , Soon-Hyung Yook

We develop a multi-patch and multi-group model that captures the dynamics of an infectious disease when the host is structured into an arbitrary number of groups and interacts into an arbitrary number of patches where the infection takes…

Populations and Evolution · Quantitative Biology 2017-11-23 Derdei Bichara , Abderrahman Iggidr

We study the spreading of an infection within an SIS epidemiological model on a network. Susceptible agents are given the opportunity of breaking their links with infected agents. Broken links are either permanently removed or reconnected…

Populations and Evolution · Quantitative Biology 2007-11-07 Damian H. Zanette , Sebastian Risau Gusman

Age-dependent dynamics is an important characteristic of many infectious diseases. Age-group epidemic models describe the infection dynamics in different age-groups by allowing to set distinct parameter values for each. However, such models…

Methodology · Statistics 2017-07-17 Rami Yaari , Itai Dattner , Amit Huppert

This paper introduces a microscopic approach to model epidemics, which can explicitly consider the consequences of individual's decisions on the spread of the disease. We first formulate a microscopic multi-agent epidemic model where every…

Multiagent Systems · Computer Science 2020-04-28 Changliu Liu

The time-dependent reproduction number Rt can be used to track pathogen transmission and to assess the efficacy of interventions. This quantity can be estimated by fitting renewal equation models to time series of infectious disease case…

Populations and Evolution · Quantitative Biology 2025-01-30 Ioana Bouros , Robin Thompson , David Gavaghan , Ben Lambert

One of the most fascinating phenomena observed in reaction-diffusion systems is the emergence of segregated solutions, i.e. population densities with disjoint supports. We analyse such a reaction cross-diffusion system. In order to prove…

Analysis of PDEs · Mathematics 2017-11-16 José A. Carrillo , Simone Fagioli , Filippo Santambrogio , Markus Schmidtchen

Meta-analytic methods may be used to combine evidence from different sources of information. Quite commonly, the normal-normal hierarchical model (NNHM) including a random-effect to account for between-study heterogeneity is utilized for…

Methodology · Statistics 2020-02-25 Christian Röver , Tim Friede

Mathematical modeling of disease spreading plays a crucial role in understanding, controlling and preventing epidemic outbreaks. In a microscopic description of the propagation of a disease over the complex network of human contacts, the…

Physics and Society · Physics 2021-10-08 Federico Malizia , Luca Gallo , Mattia Frasca , Vito Latora , Giovanni Russo

Individual contributions to the spread of an epidemic vary widely due to an individual's location in a social network and their intrinsic ability to spread or contract diseases. While the effect of heterogeneous population structure and…

Populations and Evolution · Quantitative Biology 2026-05-14 Abhay Gupta , Nicholas W. Landry

This work presents a model combining the simplest communicable and non-communicable disease models. The latter is, by far, the leading cause of sickness and death in the World, and introduces basal heterogeneity in populations where…

Populations and Evolution · Quantitative Biology 2023-03-29 M. Marvá , E. Venturino , M. C. Vera

In the absence of drugs and vaccines, policymakers use non-pharmaceutical interventions such as social distancing to decrease rates of disease-causing contact, with the aim of reducing or delaying the epidemic peak. These measures carry…

Populations and Evolution · Quantitative Biology 2021-04-22 Dylan H. Morris , Fernando W. Rossine , Joshua B. Plotkin , Simon A. Levin