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We jointly model longitudinal values of a psychometric test and diagnosis of dementia. The model is based on a continuous-time latent process representing cognitive ability. The link between the latent process and the observations is…

Statistics Theory · Mathematics 2007-06-13 Julien Ganiayre , Daniel Commenges , Luc Letenneur

The sequential treatment decisions made by physicians to treat chronic diseases are formalized in the statistical literature as dynamic treatment regimes. To date, methods for dynamic treatment regimes have been developed under the…

Methodology · Statistics 2022-02-22 Janie Coulombe , Erica E. M. Moodie , Susan M. Shortreed , Christel Renoux

Latent factor analysis via dynamical systems (LFADS) is an RNN-based variational sequential autoencoder that achieves state-of-the-art performance in denoising high-dimensional neural activity for downstream applications in science and…

Machine Learning · Computer Science 2023-09-06 Andrew R. Sedler , Chethan Pandarinath

We consider analysis of dependent functional data that are correlated because of a longitudinal-based design: each subject is observed at repeated time visits and for each visit we record a functional variable. We propose a novel…

Methodology · Statistics 2015-06-30 So Young Park , Ana-Maria Staicu

Factor analysis is a widely used statistical tool in many scientific disciplines, such as psychology, economics, and sociology. As observations linked by networks become increasingly common, incorporating network structures into factor…

Methodology · Statistics 2024-03-27 Jinming Li , Gongjun Xu , Ji Zhu

Modeling a system's temporal behaviour in reaction to external stimuli is a fundamental problem in many areas. Pure Machine Learning (ML) approaches often fail in the small sample regime and cannot provide actionable insights beyond…

Machine Learning · Computer Science 2021-06-18 Zhaozhi Qian , William R. Zame , Lucas M. Fleuren , Paul Elbers , Mihaela van der Schaar

We present a multidimensional data analysis framework for the analysis of ordinal response variables. Underlying the ordinal variables, we assume a continuous latent variable, leading to cumulative logit models. The framework includes…

Methodology · Statistics 2025-10-01 Mark de Rooij , Ligaya Breemer , Dion Woestenburg , Frank Busing

Therapeutic dialogue is not a sequence of isolated responses: client goals, motivation, resistance, and therapeutic alliance evolve over time. Yet current LLM-based mental health dialogue systems often lack explicit mechanisms for tracking…

The difference-in-differences (DID) design is widely used in observational studies to estimate the causal effect of a treatment when repeated observations over time are available. Yet, almost all existing methods assume linearity in the…

Applications · Statistics 2020-09-29 Soichiro Yamauchi

In social sciences, studies are often based on questionnaires asking participants to express ordered responses several times over a study period. We present a model-based clustering algorithm for such longitudinal ordinal data. Assuming…

Methodology · Statistics 2024-01-29 Francesco Amato , Julien Jacques , Isabelle Prim-Allaz

Mobile health studies often collect multiple within-day self-reported assessments of participants' behavior and well-being on different scales such as physical activity (continuous), pain levels (truncated), mood states (ordinal), and life…

Methodology · Statistics 2023-09-22 Debangan Dey , Rahul Ghosal , Kathleen Merikangas , Vadim Zipunnikov

Traditional LiDAR odometry (LO) systems mainly leverage geometric information obtained from the traversed surroundings to register laser scans and estimate LiDAR ego-motion, while it may be unreliable in dynamic or unstructured…

Robotics · Computer Science 2022-09-14 Shuaixin Li , Bin Tian , Zhu Xiaozhou , Gui Jianjun , Yao Wen , Guangyun Li

Research has proven that stress reduces quality of life and causes many diseases. For this reason, several researchers devised stress detection systems based on physiological parameters. However, these systems require that obtrusive sensors…

Computers and Society · Computer Science 2014-10-23 Andrey Bogomolov , Bruno Lepri , Michela Ferron , Fabio Pianesi , Alex , Pentland

Metabolic health is increasingly implicated as a risk factor across conditions from cardiology to neurology, and efficiency assessment of body composition is critical to quantitatively characterizing these relationships. 2D low dose single…

Computer Vision and Pattern Recognition · Computer Science 2022-09-29 Xin Yu , Yucheng Tang , Qi Yang , Ho Hin Lee , Riqiang Gao , Shunxing Bao , Ann Zenobia Moore , Luigi Ferrucci , Bennett A. Landman

The advent of mobile health technologies presents new challenges that existing visualizations, interactive tools, and algorithms are not yet designed to support. In dealing with uncertainty in sensor data and high-dimensional physiological…

Human-Computer Interaction · Computer Science 2016-09-28 Peter J Polack , Shang-Tse Chen , Minsuk Kahng , Kaya de Barbaro , Moushumi Sharmin , Rahul Basole , Duen Horng Chau

We consider a randomized controlled trial between two groups. The objective is to identify a population with characteristics such that the test therapy is more effective than the control therapy. Such a population is called a subgroup. This…

Methodology · Statistics 2021-12-06 Shintaro Yuki , Kensuke Tanioka , Hiroshi Yadohisa

In longitudinal studies, subjects may be lost to follow-up, or miss some of the planned visits, leading to incomplete response sequences. When the probability of non-response, conditional on the available covariates and the observed…

Methodology · Statistics 2017-07-10 Alessandra Spagnoli , Maria Francesca Marino , Marco Alfò

By subjecting a dynamical system to a series of short pulses and varying several time delays we can obtain multidimensional characteristic measures of the system. Multidimensional Kullback-Leibler response function (KLRF), which are based…

Statistical Mechanics · Physics 2010-03-24 Saar Rahav , Shaul Mukamel

Individual's general well-being is greatly impacted by mental health conditions including depression and Post-Traumatic Stress Disorder (PTSD), underscoring the importance of early detection and precise diagnosis in order to facilitate…

Machine Learning · Computer Science 2025-02-07 Himanshi Singh , Sadhana Tiwari , Sonali Agarwal , Ritesh Chandra , Sanjay Kumar Sonbhadra , Vrijendra Singh

While NLP typically treats documents as independent and unordered samples, in longitudinal studies, this assumption rarely holds: documents are nested within authors and ordered in time, forming person-indexed, time-ordered…