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In this paper we propose a new template for empirical studies intended to assess causal effects: the outcome-wide longitudinal design. The approach is an extension of what is often done to assess the causal effects of a treatment or…

Methodology · Statistics 2018-10-25 Tyler J. VanderWeele , Maya B. Mathur , Ying Chen

Integrating physiological signals such as electroencephalogram (EEG), with other data such as interview audio, may offer valuable multimodal insights into psychological states or neurological disorders. Recent advancements with Large…

Human-Computer Interaction · Computer Science 2024-08-15 Yongquan Hu , Shuning Zhang , Ting Dang , Hong Jia , Flora D. Salim , Wen Hu , Aaron J. Quigley

A large-scale dynamic network (LDN) is a source of data in many big data-related applications due to their large number of entities and large-scale dynamic interactions. They can be modeled as a high-dimensional incomplete (HDI) tensor that…

Machine Learning · Computer Science 2023-05-05 Aoling Zeng

Mobile health (mHealth) systems help researchers monitor and care for patients in real-world settings. Studies utilizing mHealth applications use Ecological Momentary Assessment (EMAs), passive sensing, and contextual features to develop…

Alzheimer's disease (AD) alters brain electrophysiology and disrupts multichannel EEG dynamics, making accurate and clinically useful EEG-based diagnosis increasingly important for screening and disease monitoring. However, many existing…

Machine Learning · Computer Science 2026-02-23 Hairong Chen , Yicheng Feng , Ziyu Jia , Samir Bhatt , Hengguan Huang

Diverse analysis approaches have been proposed to distinguish data missing due to death from nonresponse, and to summarize trajectories of longitudinal data truncated by death. We demonstrate how these analysis approaches arise from…

Methodology · Statistics 2010-01-18 Brenda F. Kurland , Laura L. Johnson , Brian L. Egleston , Paula H. Diehr

Poor sitting posture is a critical yet often overlooked factor contributing to long-term musculoskeletal disorders and physiological dysfunctions. Existing sitting posture monitoring systems, although leveraging visual, IMU, or…

Computation and Language · Computer Science 2025-09-17 Jian Gao , Fufangchen Zhao , Yiyang Zhang , Danfeng Yan

Depression is a major global public health challenge and its early identification is crucial. Social media data provides a new perspective for depression detection, but existing methods face limitations such as insufficient accuracy,…

Artificial Intelligence · Computer Science 2026-01-12 Yukun Yang

Out-of-distribution (OOD) detection remains challenging for deep learning models, particularly when test-time OOD samples differ significantly from training outliers. We propose OODD, a novel test-time OOD detection method that dynamically…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Yifeng Yang , Lin Zhu , Zewen Sun , Hengyu Liu , Qinying Gu , Nanyang Ye

Electronic health records (EHR) contain valuable longitudinal patient-level information, yet most statistical methods reduce the irregular timing of EHR codes into simple counts, thereby discarding rich temporal structure. Existing temporal…

Methodology · Statistics 2025-08-29 Parker Knight , Doudou Zhou , Zongqi Xia , Tianxi Cai , Junwei Lu

In multivariate time series systems, key insights can be obtained by discovering lead-lag relationships inherent in the data, which refer to the dependence between two time series shifted in time relative to one another, and which can be…

Machine Learning · Statistics 2023-09-20 Yichi Zhang , Mihai Cucuringu , Alexander Y. Shestopaloff , Stefan Zohren

In longitudinal studies, time-varying covariates are often endogenous, meaning their values depend on both their own history and that of the outcome variable. This violates key assumptions of Generalized Linear Mixed Effects Models (GLMMs),…

Longitudinal data are important in numerous fields, such as healthcare, sociology and seismology, but real-world datasets present notable challenges for practitioners because they can be high-dimensional, contain structured missingness…

Machine Learning · Computer Science 2024-07-01 Maksim Sinelnikov , Manuel Haussmann , Harri Lähdesmäki

In this study, we develop a latent factor model for analysing high-dimensional binary data. Specifically, a standard probit model is used to describe the regression relationship between the observed binary data and the continuous latent…

Methodology · Statistics 2024-04-15 Jiaxin Shi , Yuan Gao , Rui Pan , Hansheng Wang

Multimodal data, where different types of data are collected from the same subjects, are fast emerging in a large variety of scientific applications. Factor analysis is commonly used in integrative analysis of multimodal data, and is…

Statistics Theory · Mathematics 2021-03-31 Quefeng Li , Lexin Li

Latent class models have been successfully used to handle complex datasets in different disciplines. For longitudinal outcomes, we often get a trajectory of the outcome for each individual, and on that basis, we cluster them for a powerful…

Methodology · Statistics 2025-09-08 Chitradipa Chakraborty , Kiranmoy Das

Globally, chronic liver disease continues to be a major health concern that requires precise predictive models for prompt detection and treatment. Using the Indian Liver Patient Dataset (ILPD) from the University of California at Irvine's…

Machine Learning · Computer Science 2024-12-31 Anand Karna , Naina Khan , Rahul Rauniyar , Prashant Giridhar Shambharkar

Trial-based economic evaluations are typically performed on cross-sectional variables, derived from the responses for only the completers in the study, using methods that ignore the complexities of utility and cost data (e.g. skewness and…

Methodology · Statistics 2018-05-21 Andrea Gabrio , Michael J. Daniels , Gianluca Baio

We discuss Bayesian analysis of multivariate time series with dynamic factor models that exploit time-adaptive sparsity in model parametrizations via the latent threshold approach. One central focus is on the transfer responses of multiple…

Applications · Statistics 2022-06-07 Jouchi Nakajima , Mike West

With the rapid development of wearable device technologies, accelerometers can record minute-by-minute physical activity for consecutive days, which provides important insight into a dynamic association between the intensity of physical…

Methodology · Statistics 2024-09-06 Cheng Cao , Jiguo Cao , Hao Pan , Yunting Zhang , Fan Jiang , Xinyue Li