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Out-of-distribution (OOD) detection is crucial for safely deploying automated medical image analysis systems, as abnormal patterns in images could hamper their performance. However, OOD detection in medical imaging remains an open…

Image and Video Processing · Electrical Eng. & Systems 2025-09-18 Evi M. C. Huijben , Sina Amirrajab , Josien P. W. Pluim

One critical challenge in deploying highly performant machine learning models in real-life applications is out of distribution (OOD) detection. Given a predictive model which is accurate on in distribution (ID) data, an OOD detection system…

Machine Learning · Computer Science 2022-05-24 Conor Igoe , Youngseog Chung , Ian Char , Jeff Schneider

Recent advances in deep learning have led to breakthroughs in the development of automated skin disease classification. As we observe an increasing interest in these models in the dermatology space, it is crucial to address aspects such as…

Computer Vision and Pattern Recognition · Computer Science 2021-06-03 Hannah Kim , Girmaw Abebe Tadesse , Celia Cintas , Skyler Speakman , Kush Varshney

Unsupervised out-of-distribution (OOD) detection aims to identify out-of-domain data by learning only from unlabeled In-Distribution (ID) training samples, which is crucial for developing a safe real-world machine learning system. Current…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Ying Yang , De Cheng , Chaowei Fang , Yubiao Wang , Changzhe Jiao , Lechao Cheng , Nannan Wang

Out-of-distribution (OOD) detection is essential for ensuring the reliability of deep learning models in medical imaging applications. This work is motivated by the observation that class activation maps (CAMs) for in-distribution (ID) data…

Computer Vision and Pattern Recognition · Computer Science 2025-05-14 Yu-Jen Chen , Xueyang Li , Yiyu Shi , Tsung-Yi Ho

Out-of-distribution (OOD) detection remains challenging for deep learning models, particularly when test-time OOD samples differ significantly from training outliers. We propose OODD, a novel test-time OOD detection method that dynamically…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Yifeng Yang , Lin Zhu , Zewen Sun , Hengyu Liu , Qinying Gu , Nanyang Ye

Deep neural networks have attained remarkable performance when applied to data that comes from the same distribution as that of the training set, but can significantly degrade otherwise. Therefore, detecting whether an example is…

Computer Vision and Pattern Recognition · Computer Science 2020-04-02 Yen-Chang Hsu , Yilin Shen , Hongxia Jin , Zsolt Kira

The ability to detect Out-of-Distribution (OOD) data is important in safety-critical applications of deep learning. The aim is to separate In-Distribution (ID) data drawn from the training distribution from OOD data using a measure of…

Machine Learning · Computer Science 2022-09-21 Guoxuan Xia , Christos-Savvas Bouganis

Out-of-distribution (OoD) detection is a natural downstream task for deep generative models, due to their ability to learn the input probability distribution. There are mainly two classes of approaches for OoD detection using deep…

Machine Learning · Computer Science 2019-07-11 Yujia Huang , Sihui Dai , Tan Nguyen , Richard G. Baraniuk , Anima Anandkumar

Recent years have witnessed a rapid development of automated methods for skin lesion diagnosis and classification. Due to an increasing deployment of such systems in clinics, it has become important to develop a more robust system towards…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Deval Mehta , Yaniv Gal , Adrian Bowling , Paul Bonnington , Zongyuan Ge

Out-of-distribution (OOD) detection is crucial for ensuring reliable deployment of machine learning models. Recent advancements focus on utilizing easily accessible auxiliary outliers (e.g., data from the web or other datasets) in training.…

Machine Learning · Computer Science 2024-11-22 Haiyun Yao , Zongbo Han , Huazhu Fu , Xi Peng , Qinghua Hu , Changqing Zhang

Detecting out-of-distribution (OOD) samples is important for deploying machine learning models in safety-critical applications such as autonomous driving and robot-assisted surgery. Existing research has mainly focused on unimodal scenarios…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Hao Dong , Yue Zhao , Eleni Chatzi , Olga Fink

Out-of-distribution (OOD) detection is critical to ensuring the reliability and safety of machine learning systems. For instance, in autonomous driving, we would like the driving system to issue an alert and hand over the control to humans…

Computer Vision and Pattern Recognition · Computer Science 2024-01-24 Jingkang Yang , Kaiyang Zhou , Yixuan Li , Ziwei Liu

We introduce powerful ideas from Hyperdimensional Computing into the challenging field of Out-of-Distribution (OOD) detection. In contrast to most existing work that performs OOD detection based on only a single layer of a neural network,…

Computer Vision and Pattern Recognition · Computer Science 2022-08-31 Samuel Wilson , Tobias Fischer , Niko Sünderhauf , Feras Dayoub

Out-of-distribution (OOD) detection is essential to improve the reliability of machine learning models by detecting samples that do not belong to the training distribution. Detecting OOD samples effectively in certain tasks can pose a…

Computer Vision and Pattern Recognition · Computer Science 2023-11-02 Divyanshu Mishra , He Zhao , Pramit Saha , Aris T. Papageorghiou , J. Alison Noble

Out of distribution (OOD) detection is a crucial part of making machine learning systems robust. The ImageNet-O dataset is an important tool in testing the robustness of ImageNet trained deep neural networks that are widely used across a…

Computer Vision and Pattern Recognition · Computer Science 2022-01-25 Anugya Srivastava , Shriya Jain , Mugdha Thigle

Effective out-of-distribution (OOD) detection is crucial for reliable machine learning models, yet most current methods are limited in practical use due to requirements like access to training data or intervention in training. We present a…

Machine Learning · Computer Science 2024-03-13 Fran Jelenić , Josip Jukić , Martin Tutek , Mate Puljiz , Jan Šnajder

Deep neural networks are susceptible to generating overconfident yet erroneous predictions when presented with data beyond known concepts. This challenge underscores the importance of detecting out-of-distribution (OOD) samples in the open…

Computer Vision and Pattern Recognition · Computer Science 2023-08-31 Yiye Chen , Yunzhi Lin , Ruinian Xu , Patricio A. Vela

Out-of-distribution detection is an important capability that has long eluded vanilla neural networks. Deep Neural networks (DNNs) tend to generate over-confident predictions when presented with inputs that are significantly…

Machine Learning · Computer Science 2022-02-24 Sumedh A Sontakke , Buvaneswari Ramanan , Laurent Itti , Thomas Woo

Standard recognition approaches are unable to deal with novel categories at test time. Their overconfidence on the known classes makes the predictions unreliable for safety-critical applications such as healthcare or autonomous driving.…

Computer Vision and Pattern Recognition · Computer Science 2023-07-13 Lorenzo Li Lu , Giulia D'Ascenzi , Francesco Cappio Borlino , Tatiana Tommasi