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The synthetic control (SC) framework is widely used for observational causal inference with time-series panel data. SC has been successful in diverse applications, but existing methods typically treat the ordering of pre-intervention time…

Machine Learning · Computer Science 2026-01-07 Saeyoung Rho , Cyrus Illick , Samhitha Narasipura , Alberto Abadie , Daniel Hsu , Vishal Misra

Controlling complex physics systems is important in diverse domains. While diffusion-based methods have demonstrated advantages over classical model-based approaches and myopic sequential learning methods in achieving global trajectory…

Systems and Control · Electrical Eng. & Systems 2026-02-03 Hongyi Chen , Jingtao Ding , Jianhai Shu , Xinchun Yu , Xiaojun Liang , Yong Li , Xiao-Ping Zhang

Synthetic biology is a recent area of biological engineering, whose aim is to provide cells with novel functionalities. A number of important results regarding the development of control circuits in synthetic biology have been achieved…

Systems and Control · Electrical Eng. & Systems 2024-11-11 Antón Pardo , Sandra Díaz Seoane , Dorin A. Ionescu , Antonis Papachristodoulou , Alejandro F. Villaverde

Bridging the gap between internal and external validity is crucial for heterogeneous treatment effect estimation. Randomised controlled trials (RCTs), favoured for their internal validity due to randomisation, often encounter challenges in…

The synthetic control method (SCM) estimates causal effects in panel data with a single-treated unit by constructing a counterfactual outcome as a weighted combination of untreated control units that matches the pre-treatment trajectory. In…

Machine Learning · Statistics 2026-05-13 Yuxin Wang , Dennis Frauen , Emil Javurek , Konstantin Hess , Yuchen Ma , Stefan Feuerriegel

Difference-in-Differences (DiD) is a widely used research design that often relies on a conditional parallel trends (CPT) assumption. In contrast to settings with unconfoundedness, where causal graphs provide powerful frameworks for…

Econometrics · Economics 2026-04-15 Michael C. Knaus , Henri Pfleiderer

The average treatment effect on the treated (ATT) in a staggered-adoption panel is estimated using an intercept-augmented synthetic-control (SCM) estimator. A weighted parallel trends plus an intercept shift, together with mild regularity…

Methodology · Statistics 2025-08-08 Michael Guggisberg

Patients in clinical studies often exhibit heterogeneous treatment effect (HTE). Classical subgroup analyses provide inferential tools to test for effect modification, while modern machine learning methods estimate the Conditional Average…

Applications · Statistics 2026-01-05 Nan Miles Xi , Xin Huang , Lin Wang

The estimation of heterogeneous treatment effects in the potential outcome setting is biased when there exists model misspecification or unobserved confounding. As these biases are unobservable, what model to use when remains a critical…

Methodology · Statistics 2024-05-09 Shonosuke Sugasawa , Kosaku Takanashi , Kenichiro McAlinn , Edoardo M. Airoldi

Semantic Image Synthesis (SIS) is among the most popular and effective techniques in the field of face generation and editing, thanks to its good generation quality and the versatility is brings along. Recent works attempted to go beyond…

Computer Vision and Pattern Recognition · Computer Science 2025-04-30 Alex Ergasti , Claudio Ferrari , Tomaso Fontanini , Massimo Bertozzi , Andrea Prati

In reactive controller synthesis, a number of implementations (controllers) are possible for a given specification because of the incomplete nature of specification. To choose the most desirable one from the various options, we need to…

Logic in Computer Science · Computer Science 2019-05-28 Amol Wakankar , Paritosh K. Pandya , Rajmohan Matteplackel

In this paper, we present how to synthesize controllers to enforce $\omega$-regular properties over linear control systems affected by bounded disturbances. In particular, these controllers are synthesized based on so-called hybrid…

Systems and Control · Electrical Eng. & Systems 2023-04-18 Bingzhuo Zhong , Majid Zamani , Marco Caccamo

Despite extensive research and remarkable advancements in the control of complex dynamical networks, most studies and practical control methods limit their focus to time-invariant control schedules (TICS). This is both due to their…

Optimization and Control · Mathematics 2018-12-31 Erfan Nozari , Fabio Pasqualetti , Jorge Cortes

We propose a novel framework for synthesizing counterfactual treatment group data in a target site by integrating full treatment and control group data from a source site with control group data from the target. Departing from conventional…

Methodology · Statistics 2025-11-14 Borna Bateni , Yubai Yuan , Qi Xu , Annie Qu

Heterogeneous treatment effects (HTEs) are increasingly estimated using machine learning models that produce highly personalized predictions of treatment effects. In practice, however, predicted treatment effects are rarely interpreted,…

Applied Difference-in-Differences studies often involve outcomes that are discrete, mixed, censored, or otherwise non-continuously distributed, while policy questions frequently concern distributional effects rather than mean effects alone.…

Econometrics · Economics 2026-05-22 Nelly K. Djuazon , Emmanuel Selorm Tsyawo

The System Level Synthesis (SLS) approach facilitates distributed control of large cyberphysical networks in an easy-to-understand, computationally scalable way. We present an overview of the SLS approach and its associated extensions in…

Systems and Control · Electrical Eng. & Systems 2021-04-01 Jing Shuang Li , Carmen Amo Alonso , John C. Doyle

Synthetic control methods have gained popularity among causal studies with observational data, particularly when estimating the impacts of the interventions that are implemented to a small number of large units. Implementing the synthetic…

Methodology · Statistics 2020-05-29 Gyuhyeong Goh , Jisang Yu

We consider discrete dynamical systems and lattice models in statistical mechanics from the point of view of their symmetry groups. We describe a C program for symmetry analysis of discrete systems. Among other features, the program…

Mathematical Physics · Physics 2007-10-08 Vladimir V. Kornyak

Method validation and study design in causal inference rely on synthetic data with known counterfactuals. Existing simulators trade off distributional realism, the ability to capture mixed-type and multimodal tabular data, against causal…

Methodology · Statistics 2026-03-05 Qi Zhang , Harsh Parikh , Ashley Naimi , Razieh Nabi , Christopher Kim , Timothy Lash
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