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Uncertainty quantification is a fundamental problem in the analysis and interpretation of synthetic control (SC) methods. We develop conditional prediction intervals in the SC framework, and provide conditions under which these intervals…

Methodology · Statistics 2021-09-09 Matias D. Cattaneo , Yingjie Feng , Rocio Titiunik

Dataset condensation (DC) learns a compact synthetic dataset that enables models to match the performance of full-data training, prioritising utility over distributional fidelity. While typically explored for computational efficiency, DC…

High content imaging assays can capture rich phenotypic response data for large sets of compound treatments, aiding in the characterization and discovery of novel drugs. However, extracting representative features from high content images…

Computer Vision and Pattern Recognition · Computer Science 2023-06-13 Johan Fredin Haslum , Christos Matsoukas , Karl-Johan Leuchowius , Erik Müllers , Kevin Smith

We describe the DISC (Different Individuals, Same Clusters) design, a sampling scheme that can improve the precision of difference-in-differences (DID) estimators in settings involving repeated sampling of a population at multiple time…

Methodology · Statistics 2025-08-21 Jordan Downey , Avi Kenny

An actively controlled Susceptible-Infected-Susceptible (actSIS) contagion model is presented for studying epidemic dynamics with continuous-time feedback control of infection rates. Our work is inspired by the observation that epidemics…

Physics and Society · Physics 2020-07-06 Yunxiu Zhou , Simon A. Levin , Naomi E. Leonard

Microbiome-based stratification of healthy individuals into compositional categories, referred to as "community types", holds promise for drastically improving personalized medicine. Despite this potential, the existence of community types…

Quantitative Methods · Quantitative Biology 2016-04-27 Travis E. Gibson , Amir Bashan , Hong-Tai Cao , Scott T. Weiss , Yang-Yu Liu

We propose principled prediction intervals to quantify the uncertainty of a large class of synthetic control predictions (or estimators) in settings with staggered treatment adoption, offering precise non-asymptotic coverage probability…

Econometrics · Economics 2025-02-04 Matias D. Cattaneo , Yingjie Feng , Filippo Palomba , Rocio Titiunik

Heterogeneity is ubiquitous in stem cells (SC), cancer cells (CS), and cancer stem cells (CSC). SC and CSC heterogeneity is manifested as diverse sub-populations with self-renewing and unique regeneration capacity. Moreover, the CSC progeny…

Molecular Networks · Quantitative Biology 2024-06-19 Chong Yu , Qiong Liu , Cong Chen , Jin Wang

Despite longstanding interest, controller synthesis remains challenging for networks of heterogeneous, nonlinear agents. Moreover, the requirements for computational scalability and information privacy have become increasingly critical.…

Systems and Control · Electrical Eng. & Systems 2026-04-01 Ingyu Jang , Leila J. Bridgeman

A common approach to constructing a Synthetic Control unit is to fit on the outcome variable and covariates in pre-treatment time periods, but it has been shown by Ferman and Pinto (2019) that this approach does not provide asymptotic…

Econometrics · Economics 2024-03-07 Joseph Fry

Motivated by a recent literature on the double-descent phenomenon in machine learning, we consider highly over-parameterized models in causal inference, including synthetic control with many control units. In such models, there may be so…

Econometrics · Economics 2023-10-16 Jann Spiess , Guido Imbens , Amar Venugopal

Music-driven group choreography poses a considerable challenge but holds significant potential for a wide range of industrial applications. The ability to generate synchronized and visually appealing group dance motions that are aligned…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Nhat Le , Tuong Do , Khoa Do , Hien Nguyen , Erman Tjiputra , Quang D. Tran , Anh Nguyen

Selecting subsets of features that differentiate between two conditions is a key task in a broad range of scientific domains. In many applications, the features of interest form clusters with similar effects on the data at hand. To recover…

Machine Learning · Computer Science 2022-11-11 Ram Dyuthi Sristi , Gal Mishne , Ariel Jaffe

Suppose it is of interest to characterize effect heterogeneity of an intervention across levels of a baseline covariate using only pre- and post- intervention outcome measurements from those who received the intervention, i.e. with no…

Methodology · Statistics 2023-06-21 Zach Shahn

A hallmark of a plethora of intracellular signaling pathways is the spatial separation of activation and deactivation processes that potentially results in precipitous gradients of activated proteins. The classical Metabolic Control…

Analysis of PDEs · Mathematics 2007-05-23 Mark A. Peletier , Hans V. Westerhoff , Boris N. Kholodenko

Controlling contacts is truly challenging, and this has been a major hurdle to deploying industrial robots into unstructured/human-centric environments. More specifically, the main challenges are: (i) how to ensure stability at all times;…

Robotics · Computer Science 2020-01-17 Hung Pham , Quang-Cuong Pham

This paper gives convex conditions for synthesis of a distributed control system for large-scale networked nonlinear dynamic systems. It is shown that the technique of control contraction metrics (CCMs) can be extended to this problem by…

Systems and Control · Computer Science 2018-10-12 Humberto Stein Shiromoto , Max Revay , Ian R. Manchester

A treatment may be appropriate for some group (the ``sick" group) on whom it has a positive effect, but it can also have a detrimental effect on subjects from another group (the ``healthy" group). In a non-targeted trial both sick and…

Machine Learning · Computer Science 2025-04-23 Georgios Mavroudeas , Malik Magdon-Ismail , Kristin P. Bennett , Jason Kuruzovich

Abstract. The advancement of deep learning has coincided with the proliferation of both models and available data. The surge in dataset sizes and the subsequent surge in computational requirements have led to the development of the Dataset…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Jun-Yeong Moon , Jung Uk Kim , Gyeong-Moon Park

Clinical trials are typically run in order to understand the effects of a new treatment on a given population of patients. However, patients in large populations rarely respond the same way to the same treatment. This heterogeneity in…

Machine Learning · Statistics 2024-02-12 Alihan Hüyük , Zhaozhi Qian , Mihaela van der Schaar