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Related papers: Towards Generalist Biomedical AI

200 papers

Medical imaging provides essential visual insights for diagnosis, and multimodal large language models (MLLMs) are increasingly utilized for its analysis due to their strong generalization capabilities; however, the underlying factors…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Zhenyang Cai , Junying Chen , Rongsheng Wang , Weihong Wang , Yonglin Deng , Dingjie Song , Yize Chen , Zixu Zhang , Benyou Wang

The integration of medical imaging and clinical text has enabled the emergence of generalist artificial intelligence (AI) systems for healthcare. However, pervasive biases, such as imbalanced disease prevalence, skewed anatomical region…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Cheng Li , Weijian Huang , Jiarun Liu , Hao Yang , Qi Yang , Song Wu , Ye Li , Hairong Zheng , Shanshan Wang

The emerging trend of advancing generalist artificial intelligence, such as GPTv4 and Gemini, has reshaped the landscape of research (academia and industry) in machine learning and many other research areas. However, domain-specific…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Xiaosong Wang , Xiaofan Zhang , Guotai Wang , Junjun He , Zhongyu Li , Wentao Zhu , Yi Guo , Qi Dou , Xiaoxiao Li , Dequan Wang , Liang Hong , Qicheng Lao , Tong Ruan , Yukun Zhou , Yixue Li , Jie Zhao , Kang Li , Xin Sun , Lifeng Zhu , Shaoting Zhang

Medical data poses a daunting challenge for AI algorithms: it exists in many different modalities, experiences frequent distribution shifts, and suffers from a scarcity of examples and labels. Recent advances, including transformers and…

Following the successful paradigm shift of large language models, leveraging pre-training on a massive corpus of data and fine-tuning on different downstream tasks, generalist models have made their foray into computer vision. The…

Image and Video Processing · Electrical Eng. & Systems 2025-11-21 Andrea Moglia , Matteo Leccardi , Matteo Cavicchioli , Alice Maccarini , Marco Marcon , Luca Mainardi , Pietro Cerveri

Current artificial intelligence models for medical imaging are predominantly single modality and single disease. Attempts to create multimodal and multi-disease models have resulted in inconsistent clinical accuracy. Furthermore, training…

Biomedical multimodal assistants have the potential to unify radiology, pathology, and clinical-text reasoning, yet a critical deployment gap remains: top-performing systems are either closed-source or computationally prohibitive,…

Computation and Language · Computer Science 2026-03-03 Kai Zhang , Zhengqing Yuan , Cheng Peng , Songlin Zhao , Mengxian Lyu , Ziyi Chen , Yanfang Ye , Wei Liu , Ying Zhang , Kaleb E Smith , Lifang He , Lichao Sun , Yonghui Wu

Recent artificial intelligence (AI) systems have reached milestones in "grand challenges" ranging from Go to protein-folding. The capability to retrieve medical knowledge, reason over it, and answer medical questions comparably to…

Medical diagnostic applications require models that can process multimodal medical inputs (images, patient histories, lab results) and generate diverse outputs including both textual reports and visual content (annotations, segmentation…

Multimodal large language models (MLLMs) have shown remarkable potential in various domains, yet their application in the medical field is hindered by several challenges. General-purpose MLLMs often lack the specialized knowledge required…

Artificial Intelligence · Computer Science 2025-09-29 Guanghao Zhu , Zhitian Hou , Zeyu Liu , Zhijie Sang , Congkai Xie , Hongxia Yang

Large language models (LLMs) and large multimodal models (LMMs) promise to accelerate biomedical discovery, yet their reliability remains unclear. We introduce ARIEL (AI Research Assistant for Expert-in-the-Loop Learning), an open-source…

Multimodal large language models (MLLMs) have shown remarkable performance in vision-language tasks. However, existing MLLMs are primarily trained on generic datasets, limiting their ability to reason on domain-specific visual cues such as…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Hatef Otroshi Shahreza , Sébastien Marcel

Multimodal Large Language Models (MLLMs) have tremendous potential to improve the accuracy, availability, and cost-effectiveness of healthcare by providing automated solutions or serving as aids to medical professionals. Despite promising…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Mohammad Shahab Sepehri , Zalan Fabian , Maryam Soltanolkotabi , Mahdi Soltanolkotabi

With the advent of Vision-Language Models (VLMs), medical artificial intelligence (AI) has experienced significant technological progress and paradigm shifts. This survey provides an extensive review of recent advancements in Medical…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Beria Chingnabe Kalpelbe , Angel Gabriel Adaambiik , Wei Peng

Radiology report generation, as a key step in medical image analysis, is critical to the quantitative analysis of clinically informed decision-making levels. However, complex and diverse radiology reports with cross-source heterogeneity…

Developing artificial intelligence (AI) for clinical research requires a comprehensive data foundation that supports model training and rigorous evaluation. Here, we introduce TrialPanorama, a large-scale structured resource that aggregates…

Artificial Intelligence · Computer Science 2025-12-17 Zifeng Wang , Jiacheng Lin , Qiao Jin , Junyi Gao , Jathurshan Pradeepkumar , Pengcheng Jiang , Zhiyong Lu , Jimeng Sun

Generalist foundation models (GFMs) are renowned for their exceptional capability and flexibility in effectively generalizing across diverse tasks and modalities. In the field of medicine, while GFMs exhibit superior generalizability based…

Artificial intelligence has demonstrated significant potential in clinical decision-making; however, developing models capable of adapting to diverse real-world scenarios and performing complex diagnostic reasoning remains a major…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Ronghao Xu , Zhen Huang , Yangbo Wei , Xiaoqian Zhou , Zikang Xu , Ting Liu , Zihang Jiang , S. Kevin Zhou

The recent development of data-driven AI promises to automate medical diagnosis; however, most AI functions as 'black boxes' to physicians with limited computational knowledge. Using medical imaging as a point of departure, we conducted…

Human-Computer Interaction · Computer Science 2020-01-22 Yao Xie , Melody Chen , David Kao , Ge Gao , Xiang 'Anthony' Chen

Recent technological advances in healthcare have led to unprecedented growth in patient data quantity and diversity. While artificial intelligence (AI) models have shown promising results in analyzing individual data modalities, there is…

Artificial Intelligence · Computer Science 2024-11-07 Daan Schouten , Giulia Nicoletti , Bas Dille , Catherine Chia , Pierpaolo Vendittelli , Megan Schuurmans , Geert Litjens , Nadieh Khalili