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The mechanical behaviour of solid biological tissues has long been described using models based on classical continuum mechanics. However, the classical continuum theories of elasticity and viscoelasticity cannot easily capture the…

Biological Physics · Physics 2017-05-16 Shakti N. Menon , Cameron L. Hall , Scott W. McCue , D. L. Sean McElwain

The macroscopic properties of polymeric fluids are inherited from the material properties of the fibers embedded in the solvent. The behavior of such passive fibers in flow has been of interest in a wide range of systems, including cellular…

Soft Condensed Matter · Physics 2019-06-20 John LaGrone , Ricardo Cortez , Wen Yan , Lisa Fauci

We study the mechanics of a reversible decohesion (unzipping) of an elastic layer subjected to quasi-static end-point loading. At the micro level the system is simulated by an elastic chain of particles interacting with a rigid foundation…

Other Quantitative Biology · Quantitative Biology 2015-05-13 F. Maddalena , D. Percivale , G. Puglisi , L. Truskinovsky

Understanding cellular response to mechanical forces is immensely important for a plethora of biological processes. Focal adhesions are multi-molecular protein assemblies that connect the cell to the extracellular matrix and play a pivotal…

Biological Physics · Physics 2019-10-25 Rumi De

Dynamically crosslinked semiflexible biopolymers such as the actin cytoskeleton govern the mechanical behavior of living cells. Semiflexible biopolymers nonlinearly stiffen in response to mechanical loads, whereas the crosslinker dynamics…

Soft Condensed Matter · Physics 2019-06-05 Yuval Mulla , F. C. MacKintosh , Gijsje H. Koenderink

The cytoskeleton is an inhomogeneous network of semi-flexible filaments, which are involved in a wide variety of active biological processes. Although the cytoskeletal filaments can be very stiff and embedded in a dense and cross-linked…

Biological Physics · Physics 2019-05-24 Ines Weber , Cécile Appert-Rolland , Grégory Schehr , Ludger Santen

The buckling behavior of cylindrical shells has gained significant interest over the past century due to its rich nonlinear behavior and broad engineering applications. While the buckling of cylindrical shells under a single load (e.g.,…

Pattern Formation and Solitons · Physics 2025-04-01 Lu Lu , Sophie Leanza , Yang Liu , Ruike Renee Zhao

A closed-form description is proposed to explain nonlinear and slow dynamics effects exhibited by sandstone bars in longitudinal resonance experiments. Along with the fast subsystem of longitudinal nonlinear displacements we examine the…

Syntactic foams are composite materials frequently used in applications requiring the properties of low density and high damage tolerance. In the present work, polymer-based syntactic foams were studied under cyclic compression in order to…

Materials Science · Physics 2019-03-04 Z. Yousaf , M. J. A. Smith , P. Potluri , W. J. Parnell

Unlike most synthetic materials, biological materials often stiffen as they are deformed. This nonlinear elastic response, critical for the physiological function of some tissues, has been documented since at least the 19th century, but the…

Soft Condensed Matter · Physics 2009-11-10 Cornelis Storm , Jennifer J. Pastore , Fred C. MacKintosh , Tom C. Lubensky , Paul A. Janmey

We report on experiments aimed at comparing the hysteretic response of a Cu-Zn-Al single crystal undergoing a martensitic transition under strain-driven and stress-driven conditions. Strain-driven experiments were performed using a…

Materials Science · Physics 2007-08-21 Erell Bonnot , Ricardo Romero , Xavier Illa , Lluis Manosa , Antoni Planes , Eduard Vives

The particle contact model is important for powder simulations. Although several contact models have been proposed, their validity has not yet been well established. Therefore, we perform molecular dynamics (MD) simulations to clarify the…

Soft Condensed Matter · Physics 2024-08-09 Yuki Yoshida , Eiichiro Kokubo , Hidekazu Tanaka

We experimentally measure a three-dimensional (3D) granular system's reversibility under cyclic compression. We image the grains using a refractive-index-matched fluid, then analyze the images using the artificial intelligence of…

Soft Condensed Matter · Physics 2022-08-04 Zackery A. Benson , Anton Peshkov , Nicole Yunger Halpern , Derek C. Richardson , Wolfgang Losert

A new relaxation approach is proposed which allows for the description of stress- and strain-softening at finite strains. The model is based on the construction of a convex hull replacing the originally non-convex incremental stress…

Computational Engineering, Finance, and Science · Computer Science 2023-02-08 Maximilian Köhler , Daniel Balzani

While most chemical bonds weaken under the action of mechanical force (called slip bond behavior), nature has developed bonds that do the opposite: their lifetime increases as force is applied. While such catch bonds have been studied quite…

Soft Condensed Matter · Physics 2023-03-29 José Ruiz-Franco , Justin Tauber , Jasper van der Gucht

This study reports a general scenario for the out-of-equilibrium features of collapsing polymeric architectures. We use molecular dynamics simulations to characterize the coarsening kinetics, in bad solvent, for several macromolecular…

Soft Condensed Matter · Physics 2019-12-10 Mariarita Paciolla , Daniel J. Arismendi-Arrieta , Angel J. Moreno

This paper models stress softening during cyclic loading and unloading of an elastomer. The paper begins by remodelling the primary loading curve to include a softening function and goes on to derive non-linear transversely isotropic…

Soft Condensed Matter · Physics 2020-05-19 S. R. Rickaby , N. H. Scott

The motion involved in barrier crossing for protein folding are investigated in terms of the chain dynamics of the polymer backbone, completing the microscopic description of protein folding presented in the previous paper. Local reaction…

Soft Condensed Matter · Physics 2009-10-31 John J. Portman , Shoji Takada , Peter G. Wolynes

Network formation of associative semiflexible fibers and mixtures of fibers and colloidal particles is simulated for the Johnson-Kendall-Roberts (JKR) model of elastic contacts, and a phase diagram in terms of particle elasticity and…

Soft Condensed Matter · Physics 2013-06-13 Robert D. Groot

One of the limitations of electrospun collagen as bone-like fibrous structure is the potential collagen triple helix denaturation in the fibre state and the corresponding inadequate wet stability even after crosslinking. Here, we have…

Biological Physics · Physics 2015-09-21 M. Tarik Arafat , Giuseppe Tronci , Jie Yin , David J. Wood , Stephen J. Russell