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With the remarkable success of representation learning for prediction problems, we have witnessed a rapid expansion of the use of machine learning and deep learning for the analysis of digital pathology and biopsy image patches. However,…

Machine Learning · Computer Science 2024-03-06 David Ahmedt-Aristizabal , Mohammad Ali Armin , Simon Denman , Clinton Fookes , Lars Petersson

Medical imaging provides critical evidence for clinical diagnosis, treatment planning, and surgical decisions, yet most existing imaging models are narrowly focused and require multiple specialized networks, limiting their generalization.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Guoxin Wang , Jun Zhao , Xinyi Liu , Yanbo Liu , Xuyang Cao , Chao Li , Zhuoyun Liu , Qintian Sun , Fangru Zhou , Haoqiang Xing , Zhenhong Yang

Deep learning techniques have become widely utilized in histopathology image classification due to their superior performance. However, this success heavily relies on the availability of substantial labeled data, which necessitates…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Meng Li , Chaoyi Li , Can Peng , Brian C. Lovell

Foundational models are trained on extensive datasets to capture the general trends of a domain. However, in medical imaging, the scarcity of data makes pre-training for every domain, modality, or task challenging. Continual learning offers…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Mohammad Areeb Qazi , Munachiso S Nwadike , Ibrahim Almakky , Mohammad Yaqub , Numan Saeed

Cervical cancer remains a major malignancy, necessitating extensive and complex histopathological assessments and comprehensive support tools. Although deep learning shows promise, these models still lack accuracy and generalizability.…

Vision-language models in pathology enable multimodal case retrieval and automated report generation. Many of the models developed so far, however, have been trained on pathology reports that include information which cannot be inferred…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Ruben T. Lucassen , Tijn van de Luijtgaarden , Sander P. J. Moonemans , Gerben E. Breimer , Willeke A. M. Blokx , Mitko Veta

Vision-language models hold considerable promise for ophthalmology, but their development depends on large-scale, high-quality image-text datasets that remain scarce. We present PubMed-Ophtha, a hierarchical dataset of 102,023…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Verena Jasmin Hallitschke , Carsten Eickhoff , Philipp Berens

The Vision-Language Foundation model is increasingly investigated in the fields of computer vision and natural language processing, yet its exploration in ophthalmology and broader medical applications remains limited. The challenge is the…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Jiawei Du , Jia Guo , Weihang Zhang , Shengzhu Yang , Hanruo Liu , Huiqi Li , Ningli Wang

Dermatological diagnosis represents a complex multimodal challenge that requires integrating visual features with specialized clinical knowledge. While vision-language pretraining (VLP) has advanced medical AI, its effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2025-05-15 Siyuan Yan , Xieji Li , Ming Hu , Yiwen Jiang , Zhen Yu , Zongyuan Ge

Weakly supervised semantic segmentation (WSSS) in histopathology seeks to reduce annotation cost by learning from image-level labels, yet it remains limited by inter-class homogeneity, intra-class heterogeneity, and the region-shrinkage…

Progress in a research field can be hard to assess, in particular when many concurrent methods are proposed in a short period of time. This is the case in digital pathology, where many foundation models have been released recently to serve…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Pierre Marza , Leo Fillioux , Sofiène Boutaj , Kunal Mahatha , Christian Desrosiers , Pablo Piantanida , Jose Dolz , Stergios Christodoulidis , Maria Vakalopoulou

Contrastive Language-Image Pretraining (CLIP) models are able to capture the semantic relationship of images and texts and have enabled a wide range of applications, from image retrieval to classification. These models are trained with…

Computer Vision and Pattern Recognition · Computer Science 2023-11-09 Calvin Metzger

Early detection of eye diseases like glaucoma, macular degeneration, and diabetic retinopathy is crucial for preventing vision loss. While artificial intelligence (AI) foundation models hold significant promise for addressing these…

Computer Vision and Pattern Recognition · Computer Science 2024-09-12 Danli Shi , Weiyi Zhang , Jiancheng Yang , Siyu Huang , Xiaolan Chen , Mayinuer Yusufu , Kai Jin , Shan Lin , Shunming Liu , Qing Zhang , Mingguang He

Large vision-language models (VLMs), such as CLIP, learn rich joint image-text representations, facilitating advances in numerous downstream tasks, including zero-shot classification and text-to-image generation. Nevertheless, existing VLMs…

Computer Vision and Pattern Recognition · Computer Science 2023-02-24 Roni Paiss , Ariel Ephrat , Omer Tov , Shiran Zada , Inbar Mosseri , Michal Irani , Tali Dekel

Recent years have seen great advancements in the development of deep learning models for histopathology image analysis in digital pathology applications, evidenced by the increasingly common deployment of these models in both research and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Veena Kaustaban , Qinle Ba , Ipshita Bhattacharya , Nahil Sobh , Satarupa Mukherjee , Jim Martin , Mohammad Saleh Miri , Christoph Guetter , Amal Chaturvedi

Deep neural network models can learn clinically relevant features from millions of histopathology images. However generating high-quality annotations to train such models for each hospital, each cancer type, and each diagnostic task is…

A large-scale vision and language model that has been pretrained on massive data encodes visual and linguistic prior, which makes it easier to generate images and language that are more natural and realistic. Despite this, there is still a…

Computer Vision and Pattern Recognition · Computer Science 2025-02-20 Hao Huang , Shuaihang Yuan , Yu Hao , Congcong Wen , Yi Fang

Retinal image analysis is crucial for diagnosing and treating eye diseases, yet generating accurate medical reports from images remains challenging due to variability in image quality and pathology, especially with limited labeled data.…

Computer Vision and Pattern Recognition · Computer Science 2024-12-24 Teja Krishna Cherukuri , Nagur Shareef Shaik , Jyostna Devi Bodapati , Dong Hye Ye

Contrastive pretraining can substantially increase model generalisation and downstream performance. However, the quality of the learned representations is highly dependent on the data augmentation strategy applied to generate positive…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Mélanie Roschewitz , Fabio De Sousa Ribeiro , Tian Xia , Galvin Khara , Ben Glocker

Concept-based models naturally lend themselves to the development of inherently interpretable skin lesion diagnosis, as medical experts make decisions based on a set of visual patterns of the lesion. Nevertheless, the development of these…

Computer Vision and Pattern Recognition · Computer Science 2024-03-07 Cristiano Patrício , Luís F. Teixeira , João C. Neves