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Vision-language models have emerged as a powerful tool for previously challenging multi-modal classification problem in the medical domain. This development has led to the exploration of automated image description generation for…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Mansi Kakkar , Dattesh Shanbhag , Chandan Aladahalli , Gurunath Reddy M

Foundation models have recently gained tremendous popularity in medical image analysis. State-of-the-art methods leverage either paired image-text data via vision-language pre-training or unpaired image data via self-supervised pre-training…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Lei Zhu , Jun Zhou , Rick Siow Mong Goh , Yong Liu

Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ravi Mosalpuri , Mohammed Abdelsamea , Ahmed Karam Eldaly

This paper presents a novel approach for automatically generating image descriptions: visual detectors, language models, and multimodal similarity models learnt directly from a dataset of image captions. We use multiple instance learning to…

Computer Vision and Pattern Recognition · Computer Science 2016-02-22 Hao Fang , Saurabh Gupta , Forrest Iandola , Rupesh Srivastava , Li Deng , Piotr Dollár , Jianfeng Gao , Xiaodong He , Margaret Mitchell , John C. Platt , C. Lawrence Zitnick , Geoffrey Zweig

Digital histology images are amenable to the application of convolutional neural network (CNN) for analysis due to the sheer size of pixel data present in them. CNNs are generally used for representation learning from small image patches…

Image and Video Processing · Electrical Eng. & Systems 2019-07-24 Muhammad Shaban , Ruqayya Awan , Muhammad Moazam Fraz , Ayesha Azam , David Snead , Nasir M. Rajpoot

Medical contrastive vision-language pre-training (VLP) has demonstrated significant potential in improving performance on downstream tasks. Traditional approaches typically employ contrastive learning, treating paired image-report samples…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Phuoc-Nguyen Bui , Toan Duc Nguyen , Junghyun Bum , Duc-Tai Le , Hyunseung Choo

Cell-level dense prediction is central to computational pathology, but remains challenging due to fine-grained histological structures, strong domain shifts, and costly dense annotations. Existing ViT-based pathology foundation models rely…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Weiming Chen , Xitong Ling , Zhenyang Cai , Xidong Wang , Jiawen Li , Tian Guan , Benyou Wang , Yonghong He

Foundation models, often pre-trained with large-scale data, have achieved paramount success in jump-starting various vision and language applications. Recent advances further enable adapting foundation models in downstream tasks efficiently…

Computer Vision and Pattern Recognition · Computer Science 2023-06-19 Dequan Wang , Xiaosong Wang , Lilong Wang , Mengzhang Li , Qian Da , Xiaoqiang Liu , Xiangyu Gao , Jun Shen , Junjun He , Tian Shen , Qi Duan , Jie Zhao , Kang Li , Yu Qiao , Shaoting Zhang

As medical diagnoses increasingly leverage multimodal data, machine learning models are expected to effectively fuse heterogeneous information while remaining robust to missing modalities. In this work, we propose a novel multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Yi Gu , Kuniaki Saito , Jiaxin Ma

When captioning an image, people describe objects in diverse ways, such as by using different terms and/or including details that are perceptually noteworthy to them. Descriptions can be especially unique across languages and cultures.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Kyle Buettner , Jacob T. Emmerson , Adriana Kovashka

Microscopic interpretation of histopathology images underlies many important diagnostic and treatment decisions. While advances in vision-language modeling raise new opportunities for analysis of such images, the gigapixel-scale size of…

Deep learning has recently gained popularity in digital pathology due to its high prediction quality. However, the medical domain requires explanation and insight for a better understanding beyond standard quantitative performance…

Image and Video Processing · Electrical Eng. & Systems 2020-04-28 Miriam Hägele , Philipp Seegerer , Sebastian Lapuschkin , Michael Bockmayr , Wojciech Samek , Frederick Klauschen , Klaus-Robert Müller , Alexander Binder

The integration of artificial intelligence (AI) with radiology marks a transformative era in medicine. Vision foundation models have been adopted to enhance radiologic imaging analysis. However, the distinct complexities of radiologic 2D…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Zhixiu Lu , Hailong Li , Nehal A. Parikh , Jonathan R. Dillman , Lili He

Existing deep learning models for defining pathology from clinical imaging data rely on expert annotations and lack generalization capabilities in open clinical environments. Here, we present a generalizable vision-language model for…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Hao Yang , Hong-Yu Zhou , Jiarun Liu , Weijian Huang , Cheng Li , Zhihuan Li , Yuanxu Gao , Qiegen Liu , Yong Liang , Qi Yang , Song Wu , Tao Tan , Hairong Zheng , Kang Zhang , Shanshan Wang

The integration of artificial intelligence into digital pathology has the potential to automate and improve various tasks, such as image analysis and diagnostic decision-making. Yet, the inherent variability of tissues, together with the…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Ariel Larey , Nati Daniel , Eliel Aknin , Yael Fisher , Yonatan Savir

Existing vision-text contrastive learning like CLIP aims to match the paired image and caption embeddings while pushing others apart, which improves representation transferability and supports zero-shot prediction. However, medical…

Computer Vision and Pattern Recognition · Computer Science 2022-10-20 Zifeng Wang , Zhenbang Wu , Dinesh Agarwal , Jimeng Sun

Medical vision-language pretraining (VLP) that leverages naturally-paired medical image-report data is crucial for medical image analysis. However, existing methods struggle to accurately characterize associations between images and…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Xinjie Liang , Xiangyu Li , Fanding Li , Jie Jiang , Qing Dong , Wei Wang , Kuanquan Wang , Suyu Dong , Gongning Luo , Shuo Li

Content generation modeling has emerged as a promising direction in computational pathology, offering capabilities such as data-efficient learning, synthetic data augmentation, and task-oriented generation across diverse diagnostic tasks.…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Yuan Zhang , Xinfeng Zhang , Xiaoming Qi , Xinyu Wu , Feng Chen , Guanyu Yang , Huazhu Fu

Generative models have been applied in the medical imaging domain for various image recognition and synthesis tasks. However, a more controllable and interpretable image synthesis model is still lacking yet necessary for important…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Jiarong Ye , Yuan Xue , Peter Liu , Richard Zaino , Keith Cheng , Xiaolei Huang

Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song
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