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In quantitative genetics, statistical modeling techniques are used to facilitate advances in the understanding of which genes underlie agronomically important traits and have enabled the use of genome-wide markers to accelerate genetic…

Methodology · Statistics 2021-10-29 Suyoung Park , Alexander E. Lipka , Daniel J. Eck

A deep learning network was used to predict future blood glucose levels, as this can permit diabetes patients to take action before imminent hyperglycaemia and hypoglycaemia. A sequential model with one long-short-term memory (LSTM) layer,…

Machine Learning · Computer Science 2018-09-12 Qingnan Sun , Marko V. Jankovic , Lia Bally , Stavroula G. Mougiakakou

This study presents a web-based interactive health risk prediction tool designed to assess diabetes risk using machine learning models. Built on the 2015 CDC BRFSS dataset, the study evaluates models including Logistic Regression, Random…

Machine Learning · Computer Science 2025-05-12 Udaya Allani

Early detection of chronic diseases is beneficial to healthcare by providing a golden opportunity for timely interventions. Although numerous prior studies have successfully used machine learning (ML) models for disease diagnoses, they…

Computers and Society · Computer Science 2024-10-07 Di Wang , Yidan Hu , Eng Sing Lee , Hui Hwang Teong , Ray Tian Rui Lai , Wai Han Hoi , Chunyan Miao

Health professionals can use natural language processing (NLP) technologies when reviewing electronic health records (EHR). Machine learning free-text classifiers can help them identify problems and make critical decisions. We aim to…

Computation and Language · Computer Science 2018-09-18 Boyi Yang , Adam Wright

Leveraging health administrative data (HAD) datasets for predicting the risk of chronic diseases including diabetes has gained a lot of attention in the machine learning community recently. In this paper, we use the largest health records…

Applications · Statistics 2019-04-09 Mathieu Ravaut , Hamed Sadeghi , Kin Kwan Leung , Maksims Volkovs , Laura C. Rosella

Background: Predictive modeling is a key component of solutions to many healthcare problems. Among all predictive modeling approaches, machine learning methods often achieve the highest prediction accuracy, but suffer from a long-standing…

Machine Learning · Computer Science 2018-12-10 Gang Luo

Diabetes has a long asymptomatic period which can often remain undiagnosed for multiple years. In this study, we trained a deep learning model to detect new-onset diabetes using 12-lead ECG and readily available demographic information. To…

Machine Learning · Computer Science 2025-12-01 Hao Zhang , Neil Jethani , Aahlad Puli , Leonid Garber , Lior Jankelson , Yindalon Aphinyanaphongs , Rajesh Ranganath

This paper studies the problem of statistical inference for genetic relatedness between binary traits based on individual-level genome-wide association data. Specifically, under the high-dimensional logistic regression models, we define…

Methodology · Statistics 2022-10-06 Rong Ma , Zijian Guo , T. Tony Cai , Hongzhe Li

This paper attempts to answer a "simple question" in building predictive models using machine learning algorithms. Although diagnostic and predictive models for various diseases have been proposed using data from large cohort studies and…

Machine Learning · Computer Science 2024-09-04 Isao Goto

Detecting Type 2 Diabetes (T2D) and Prediabetes (PD) is a real challenge for medicine due to the absence of pathogenic symptoms and the lack of known associated risk factors. Even though some proposals for machine learning models enable the…

Machine Learning · Computer Science 2024-07-02 Enzo Rucci , Gonzalo Tittarelli , Franco Ronchetti , Jorge F. Elgart , Laura Lanzarini , Juan José Gagliardino

Diabetes mellitus (DM) is a global health issue of significance that must be diagnosed as early as possible and managed well. This study presents a framework for diabetes prediction using Machine Learning (ML) models, complemented with…

Machine Learning · Computer Science 2025-02-13 Pir Bakhsh Khokhar , Viviana Pentangelo , Fabio Palomba , Carmine Gravino

Motivation: Spontaneous adverse event reports have a high potential for detecting adverse drug reactions. However, due to their dimension, exploring such databases requires statistical methods. In this context, disproportionality measures…

Applications · Statistics 2015-06-19 Matthieu Marbac , Pascale Tubert-Bitter , Mohammed Sedki

Type 1 diabetes (T1D) management can be significantly enhanced through the use of predictive machine learning (ML) algorithms, which can mitigate the risk of adverse events like hypoglycemia. Hypoglycemia, characterized by blood glucose…

Quantitative Methods · Quantitative Biology 2025-04-02 Beyza Cinar , Jennifer Daniel Onwuchekwa , Maria Maleshkova

Describing dynamic medical systems using machine learning is a challenging topic with a wide range of applications. In this work, the possibility of modeling the blood glucose level of diabetic patients purely on the basis of measured data…

Machine Learning · Computer Science 2023-03-10 David Jödicke , Daniel Parra , Gabriel Kronberger , Stephan Winkler

The identification of most relevant clinical criteria related to low back pain disorders may aid the evaluation of the nature of pain suffered in a way that usefully informs patient assessment and treatment. Data concerning low back pain…

Methodology · Statistics 2018-02-06 Michael Fop , Keith Smart , Thomas Brendan Murphy

Nonlinear mixed effects models represent a powerful tool to simultaneously analyze data from several individuals. In this study a compartmental model of leucine kinetics is examined and extended with a stochastic differential equation to…

Quantitative Methods · Quantitative Biology 2011-01-05 Martin Berglund , Mikael Sunnåker , Martin Adiels , Mats Jirstrand , Bernt Wennberg

Effective management of Type 1 Diabetes requires continuous glucose monitoring and precise insulin adjustments to prevent hyperglycemia and hypoglycemia. With the growing adoption of wearable glucose monitors and mobile health applications,…

Machine Learning · Computer Science 2026-01-22 Giorgia Rigamonti , Mirko Paolo Barbato , Davide Marelli , Paolo Napoletano

Diabetic retinopathy is one of the most threatening complications of diabetes that leads to permanent blindness if left untreated. One of the essential challenges is early detection, which is very important for treatment success.…

Machine Learning · Computer Science 2020-03-06 Borys Tymchenko , Philip Marchenko , Dmitry Spodarets

Automatic classification of diabetic retinopathy from retinal images has been widely studied using deep neural networks with impressive results. However, there is a clinical need for estimation of the uncertainty in the classifications, a…

Computer Vision and Pattern Recognition · Computer Science 2022-02-03 Joel Jaskari , Jaakko Sahlsten , Theodoros Damoulas , Jeremias Knoblauch , Simo Särkkä , Leo Kärkkäinen , Kustaa Hietala , Kimmo Kaski