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We propose a novel semiparametric model for the joint distribution of a continuous longitudinal outcome and the baseline covariates using an enriched Dirichlet process (EDP) prior. This joint model decomposes into a linear mixed model for…

Methodology · Statistics 2018-06-08 Bret Zeldow , James Flory , Alisa Stephens-Shields , Marsha Raebel , Jason Roy

Clinical trial registries can be used to monitor the production of trial evidence and signal when systematic reviews become out of date. However, this use has been limited to date due to the extensive manual review required to search for…

Information Retrieval · Computer Science 2018-03-01 Didi Surian , Adam G. Dunn , Liat Orenstein , Rabia Bashir , Enrico Coiera , Florence T. Bourgeois

The recent increase in morbidity is primarily due to chronic diseases including Diabetes, Heart disease, Lung cancer, and brain tumours. The results for patients can be improved, and the financial burden on the healthcare system can be…

Machine Learning · Computer Science 2025-02-18 Sri Varsha Mulakala , G. Neeharika , P. Vinay Kumar , A. Bhargava Kiran

Type 2 diabetes mellitus (T2DM) is a chronic disease that often results in multiple complications. Risk prediction and profiling of T2DM complications is critical for healthcare professionals to design personalized treatment plans for…

Machine Learning · Computer Science 2019-04-03 Bin Liu , Ying Li , Soumya Ghosh , Zhaonan Sun , Kenney Ng , Jianying Hu

Diabetes is a chronic disorder identified by the high sugar level in the blood that can cause various different disorders such as kidney failure, heart attack, sightlessness, and stroke. Developments in the healthcare domain by facilitating…

Machine Learning · Computer Science 2024-11-05 Vahideh Hayyolalam , Öznur Özkasap

Phase I early-phase clinical studies aim at investigating the safety and the underlying dose-toxicity relationship of a drug or combination. While little may still be known about the compound's properties, it is crucial to consider…

Methodology · Statistics 2022-09-13 Christian Röver , Moreno Ursino , Tim Friede , Sarah Zohar

Advances in data collecting technologies in genomics have significantly increased the need for tools designed to study the genetic basis of many diseases. Effective statistical methods should excel in both prediction accuracy and biomarker…

Methodology · Statistics 2025-11-13 Anthony-Alexander Christidis , Stefan Van Aelst , Ruben Zamar

The onset of several silent, chronic diseases such as diabetes can be detected only through diagnostic tests. Due to cost considerations, self-reported outcomes are routinely collected in lieu of expensive diagnostic tests in large-scale…

Applications · Statistics 2015-09-15 Xiangdong Gu , Yunsheng Ma , Raji Balasubramanian

When investigators seek to estimate causal effects, they often assume that selection into treatment is based only on observed covariates. Under this identification strategy, analysts must adjust for observed confounders. While basic…

Applications · Statistics 2019-01-09 Luke Keele , Dylan Small

Computer-aided diagnosis (CAD), a vibrant medical imaging research field, is expanding quickly. Because errors in medical diagnostic systems might lead to seriously misleading medical treatments, major efforts have been made in recent years…

Machine Learning · Computer Science 2023-08-04 Farzaneh Tajidini , Mohammad-Javad Kheiri

When searching for gene pathways leading to specific disease outcomes, additional information on gene characteristics is often available that may facilitate to differentiate genes related to the disease from irrelevant background when…

Machine Learning · Statistics 2018-09-10 Yunpeng Zhao , Qing Pan , Chengan Du

The increasing number of diabetic patients is a serious issue in society today, which has significant negative impacts on people's health and the country's financial expenditures. Because diabetes may develop into potential serious…

Artificial Intelligence · Computer Science 2024-04-18 Ziyi Zhou , Ming Cheng , Yanjun Cui , Xingjian Diao , Zhaorui Ma

Diabetes foot ulceration (DFU) and amputation are a cause of significant morbidity. The prevention of DFU may be achieved by the identification of patients at risk of DFU and the institution of preventative measures through education and…

When estimating causal effects using observational data, it is desirable to replicate a randomized experiment as closely as possible by obtaining treated and control groups with similar covariate distributions. This goal can often be…

Methodology · Statistics 2010-10-28 Elizabeth A. Stuart

Data imbalance between common and rare diseases during model training often causes intelligent diagnosis systems to have biased predictions towards common diseases. The state-of-the-art approaches apply a two-stage learning framework to…

Computer Vision and Pattern Recognition · Computer Science 2022-07-15 Chenghua Zeng , Huijuan Lu , Kanghao Chen , Ruixuan Wang , Wei-Shi Zheng

Data labeling is currently a time-consuming task that often requires expert knowledge. In research settings, the availability of correctly labeled data is crucial to ensure that model predictions are accurate and useful. We propose…

Machine Learning · Computer Science 2018-12-31 Marina Bendersky , Joy Wu , Tanveer Syeda-Mahmood

Classification, the process of assigning a label (or class) to an observation given its features, is a common task in many applications. Nonetheless in most real-life applications, the labels can not be fully explained by the observed…

Machine Learning · Statistics 2018-11-07 Johan Barthélemy , Morgane Dumont , Timoteo Carletti

This paper proposes a new method for analysis of adverse event data in clinical trials. The method is illustrated by application to data on 4 phase III clinical trials, two on breast cancer and two on diabetes mellitus.

Applications · Statistics 2018-06-04 Sharayu Paranjpe , Anil Gore

The purpose of this research report is to present the our learning curve and the exposure to the Machine Learning life cycle, with the use of a Kaggle binary classification data set and taking to explore various techniques from…

Machine Learning · Computer Science 2021-05-25 Mohamed Hamama

Coronary heart disease, which is a form of cardiovascular disease (CVD), is the leading cause of death worldwide. The odds of survival are good if it is found or diagnosed early. The current report discusses a comparative approach to the…

Computer Vision and Pattern Recognition · Computer Science 2021-12-03 Kelvin Kwakye , Emmanuel Dadzie
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