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Dengue, which affects millions of people each year, is one of the most common diseases transmitted by infected \textit{Aedes aegypti} mosquitoes. In the Philippines, the annual economic cost of dengue infections is estimated at around PHP…

Optimization and Control · Mathematics 2026-01-19 Kyrho Corum , Renier Mendoza , Victoria May P. Mendoza , Arrianne Crystal Velasco

Vector-borne diseases cause more than 1 million deaths annually. Estimates of epidemic risk at high spatial resolutions can enable effective public health interventions. Our goal is to identify the risk of importation of such diseases into…

Social and Information Networks · Computer Science 2019-08-08 Meysam Ghaffari , Ashok Srinivasan , Anuj Mubayi , Xiuwen Liu , Krishnan Viswanathan

We consider a susceptible, infected, and recovered infectious disease model which incorporates a vaccination rate. In particular, we study the problem of choosing the vaccination rate in order to reduce the number of infected individuals to…

Analysis of PDEs · Mathematics 2021-08-30 Ryan Hynd , Dennis Ikpe , Terrance Pendleton

We propose a mathematical framework, based on conic geometric programming, to control a susceptible-infected-susceptible viral spreading process taking place in a directed contact network with unknown contact rates. We assume that we have…

Optimization and Control · Mathematics 2014-12-09 Shuo Han , Victor M. Preciado , Cameron Nowzari , George J. Pappas

We investigate the time-optimal control problem in SIR (Susceptible-Infected-Recovered) epidemic models, focusing on different control policies: vaccination, isolation, culling, and reduction of transmission. Applying the Pontryagin's…

Optimization and Control · Mathematics 2017-06-15 Luca Bolzoni , Elena Bonacini , Cinzia Soresina , Maria Groppi

The release of Wolbachia-infected mosquitoes is a promising strategy for controlling Aedes aegypti populations, but exposure to high temperatures can induce temporary infection loss and compromise long-term persistence. In this work, we…

Populations and Evolution · Quantitative Biology 2026-02-10 Jéssica C. S. Alves , Christian E. Schaerer , Cláudia P. Ferreira

Mosquitoes are vectors of many human diseases. In particular, Aedes \ae gypti (Linnaeus) is the main vector for Chikungunya, Dengue, and Zika viruses in Latin America and it represents a global threat. Public health policies that aim at…

Machine Learning · Statistics 2018-05-08 J. M. Scavuzzo , F. Trucco , M. Espinosa , C. B. Tauro , M. Abril , C. M. Scavuzzo , A. C. Frery

In this paper we describe the dynamics of a vector-borne relapsing disease, such as tick-borne relapsing fever, using the methods of compartmental models. After some motivation, model description, and a brief overview of the theory of…

Dynamical Systems · Mathematics 2016-08-24 Cody Palmer , Erin Landguth , Emily Stone , Tammi Johnson

Over 50% of the world population is at risk of mosquito-borne diseases. Female Ae. aegypti mosquito species transmit Zika, Dengue, and Chikungunya. The spread of these diseases correlate positively with the vector population, and this…

Populations and Evolution · Quantitative Biology 2019-11-28 Oladimeji Mudele , Fabio M. Bayer , Lucas Zanandrez , Alvaro E. Eiras , Paolo Gamba

Wolbachia is a genus of endosymbiotic bacteria that can infect mosquitoes and reduce their ability to transmit dengue virus. Although the bacterium is transmitted vertically from infected mothers to their offspring, it can be difficult to…

Populations and Evolution · Quantitative Biology 2015-10-06 Ling Xue , Carrie A. Manore , Panpim Thongsripong , James M. Hyman

The emergence of mutant lineages within a viral species has become a public health problem, as the existing treatments and drugs are usually more effective on the original lineages than in the mutant ones. The following manuscript presents…

Scientists have been seeking ways to use Wolbachia to eliminate the mosquitoes that spread human diseases. Could Wolbachia be the determining factor in controlling the mosquito-borne infectious diseases? To answer this question…

Analysis of PDEs · Mathematics 2020-06-30 yunfeng Liu , Zhiming Guo , Mohammad El Smaily , Lin Wang

The Sterile Insect Technique (SIT) is a biological pest control technique based on the release into the environment of sterile males of the insect species whose population is to be controlled. The entire SIT process involves mass-rearing…

Sound · Computer Science 2024-06-03 Javier Naranjo-Alcazar , Jordi Grau-Haro , David Almenar , Pedro Zuccarello

In this paper, a novel West Nile Virus model looking upon the infected birds as monitoring threshold, for the mosquitoes and birds with impulsive state feedback control is considered. We obtain sufficient conditions of the global…

Dynamical Systems · Mathematics 2016-04-28 Lin-Fei Nie , Jing-Yun Shen

Dengue is a vector borne disease transmitted to humans by {\it{Aedes Aegypti}} mosquitoes carrying Dengue virus of different serotypes. Primarily an urban epidemic, Dengue exhibits complex spatial and temporal dynamics, influenced by many…

Populations and Evolution · Quantitative Biology 2015-04-30 Murali Krishna Enduri , Shivakumar Jolad

Dengue remains a major global public health concern due to its high mortality and economic burden. Mathematical modeling is essential to understand its transmission mechanisms and for evaluating intervention strategies. In this paper, we…

Populations and Evolution · Quantitative Biology 2026-04-28 Sourav Banerjee , Thomas Götz , Satyananda Panda

According to the World Health Organization, dengue fever is the most important mosquito-borne disease of humans, and it is currently estimated that there may be 50 - 100 million yearly dengue infections worldwide. For the purpose to provide…

Populations and Evolution · Quantitative Biology 2016-08-10 L. S. Barsante , K. S. Paixão , K. H. Laass , R. T. N. Cardoso , Á. E. Eiras , J. L. Acebal

Traditional studies about disease dynamics have focused on global stability issues, due to their epidemiological importance. We study a classical SIR-SI model for arboviruses in two different directions: we begin by describing an…

Populations and Evolution · Quantitative Biology 2014-08-28 Max O. Souza

Malaria is a mosquito-borne, lethal disease that affects millions and kills hundreds of thousands of people each year. In this paper, we develop a model for allocating malaria interventions across geographic regions and time, subject to…

Populations and Evolution · Quantitative Biology 2023-09-28 Harry J. Dudley , Abhishek Goenka , Cesar J. Orellana , Susan E. Martonosi

In this paper, we consider an optimal distributed control problem for a reaction-diffusion-based SIR epidemic model with human behavioral effects. We develop a model wherein non-pharmaceutical intervention methods are implemented, but a…

Analysis of PDEs · Mathematics 2025-02-11 Marcelo Bongarti , Christian Parkinson , Weinan Wang
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